Keplat (Ketoprofen)

Ketoprofen blocks the activity of cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, which are essential for producing prostaglandins. By lowering prostaglandin levels, it diminishes inflammation, pain signaling, and swelling at the site where the patch is applied.

The appropriate dose and duration of Keplat are determined by the prescribing healthcare professional based on the patient’s condition, severity of symptoms, and individual response. Patients should follow the prescriber’s instructions and not alter the dosing regimen on their own.

Safety of ketoprofen patches during pregnancy or lactation has not been fully established. Healthcare providers generally advise caution and may recommend alternative therapies, especially in the first trimester or while nursing, to avoid potential risks to the fetus or infant.

To place an order, submit an enquiry on the Keplat product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.

Keplat offers a transdermal delivery system, which can provide targeted analgesia with reduced systemic exposure compared with oral NSAIDs. This may lower the risk of gastrointestinal side effects, but skin‑related reactions are more common. Choice of therapy depends on patient preference, clinical profile, and the need for localized versus systemic treatment.

Keplat patches should be stored at room temperature, below 25 °C, in their original packaging. Keep them away from moisture, direct sunlight, and heat sources. Do not expose the patches to extreme temperatures or humidity, as this may affect adhesion and drug stability.

The patch is applied to clean, dry, intact skin on the affected area. Remove any hair or ointments that could interfere with adhesion. Press firmly for several seconds to ensure contact, and leave the patch in place for the prescribed duration, typically 12–24 hours, before removal and disposal.

Serious risks include severe skin reactions such as Stevens‑Johnson syndrome, gastrointestinal ulceration or bleeding, hepatic dysfunction, renal impairment, cardiovascular events, and anaphylaxis. Patients should seek immediate medical attention if they experience widespread rash, severe abdominal pain, unexplained swelling, or signs of an allergic reaction.

Keplat should be avoided in individuals with known hypersensitivity to ketoprofen or other NSAIDs, those with active gastrointestinal ulcers, severe renal or hepatic disease, uncontrolled hypertension, or a history of severe cardiovascular events. Pregnant women, especially in the first trimester, and breastfeeding mothers should consult their physician before use.