Keratosis (Urea)

Urea acts as a keratolytic by breaking down the protein bonds within the outer skin layer, which loosens hardened keratin. At the same time it functions as a humectant, drawing water into the epidermis and increasing moisture content, which together facilitate desquamation and improve skin texture.

The exact amount and frequency of application are determined by the prescribing healthcare professional. Generally, a thin layer is applied to the affected area once or twice daily, but the prescriber may adjust the regimen based on the severity of the condition and individual response.

Safety data for topical urea in pregnancy and lactation are limited. Women who are pregnant or breastfeeding should discuss potential risks and benefits with their healthcare provider before starting Keratosis, and use it only if the expected benefit justifies any possible risk.

To request Keratosis, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Keratosis (urea) offers both keratolytic and humectant properties, whereas agents such as salicylic acid or lactic acid primarily focus on keratin breakdown. Urea’s dual action can provide better moisturisation while softening thickened skin, making it suitable for patients who need both exfoliation and hydration.

Keratosis should be stored at room temperature, away from direct sunlight and moisture. Keep the product in its original packaging until use, and ensure the container is tightly closed to maintain stability and prevent contamination.

Apply Keratosis to clean, dry skin. Dispense a thin layer onto the affected area and gently massage until absorbed. Follow the frequency advised by the prescriber, typically once or twice daily, and avoid covering the treated skin with occlusive dressings unless instructed otherwise.

The most serious adverse events include allergic contact dermatitis, which may present as swelling, rash or hives, and blister formation that can become infected. Although rare, extensive systemic absorption could potentially disturb electrolyte balance, so any unexpected systemic symptoms should prompt immediate medical evaluation.

Keratosis should be avoided in individuals with known hypersensitivity to urea or any excipients in the formulation. It is also not recommended for use on broken, infected or inflamed skin, and caution is advised for children, pregnant or breastfeeding women unless directed by a healthcare professional.