Product image of Kerlone (Betaxolol Hydrochloride) supplied by GNH India

Kerlone

Active Ingredient:
Betaxolol Hydrochloride
Origin:
EU

Kerlone (Betaxolol Hydrochloride)

Betaxolol Hydrochloride, the active ingredient in Kerlone, is a beta blocker presented as an oral tablet for oral use. It is employed to lower elevated blood pressure and to relieve chest pain associated with angina pectoris in adult patients.

GNH India supplies Kerlone as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides reliable global distribution, ensuring product integrity from manufacturing to end‑user delivery.

Manufacturer / TM Owner

Cheplapharm Arzneimittel Gmbh

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Betaxolol Hydrochloride acts on the cardiovascular system to control blood pressure and heart workload.

  • Hypertension: reduces systolic and diastolic blood pressure, helping to prevent cardiovascular complications.
  • Angina pectoris: decreases myocardial oxygen demand, alleviating chest pain during exertion.
  • Ischemic heart disease: improves exercise tolerance by lowering heart rate and contractility.

How It Works

  • Betaxolol Hydrochloride selectively antagonizes β1‑adrenergic receptors in cardiac tissue, inhibiting catecholamine‑induced stimulation. This reduces heart rate, myocardial contractile force, and renin release from the kidneys, leading to decreased cardiac output and lower systemic vascular resistance, which together lower arterial blood pressure. The selectivity for β1 over β2 receptors minimizes bronchial effects, making it suitable for patients without severe asthma.

Side Effects

Betaxolol Hydrochloride may cause a range of adverse reactions, varying from mild to serious.

Common Side Effects

  • Fatigue: feeling of tiredness or reduced energy.
  • Dizziness: light‑headed sensation, especially upon standing.
  • Cold extremities: reduced blood flow to hands and feet.
  • Headache: mild to moderate head pain.

Serious or Rare Side Effects

  • Severe bradycardia: markedly low heart rate requiring medical attention.
  • Heart block: impairment of electrical conduction in the heart.
  • Allergic reaction: rash, itching, swelling, or anaphylaxis.

Precautions & Warnings

When prescribing Betaxolol Hydrochloride, clinicians should consider several precautionary measures to ensure patient safety.

  • Monitor blood pressure: check regularly to assess therapeutic response.
  • Assess heart rate: watch for excessive bradycardia, especially in patients with conduction disorders.
  • Use cautiously in asthma: β1 selectivity reduces but does not eliminate risk of bronchospasm.
  • Adjust dose in renal impairment: reduced clearance may increase drug exposure.
  • Avoid abrupt discontinuation: tapering may prevent rebound hypertension.
  • Store below 25°C: keep in the original packaging, protect from moisture.

Avoid Interactions

Betaxolol Hydrochloride can interact with other medicines, altering its efficacy or safety profile.

Major Interactions (Avoid)

  • Other β‑blockers: additive bradycardia and hypotension.
  • Non‑dihydropyridine calcium channel blockers (e.g., verapamil, diltiazem): increased risk of heart block.
  • Antiarrhythmic agents (class I and III): may potentiate cardiac conduction disturbances.

Moderate Interactions (Monitor Closely)

  • NSAIDs: may reduce antihypertensive effect.
  • Diuretics: can enhance hypotensive response.
  • CYP2D6 inhibitors (e.g., fluoxetine, paroxetine): may increase betaxolol plasma levels.
  • Antidiabetic drugs: beta‑blockers may mask hypoglycemia symptoms.

Frequently Asked Questions

Kerlone contains betaxolol hydrochloride, a beta‑blocker indicated for management of hypertension and angina pectoris in adult patients. It works by reducing heart rate and blood pressure, helping to prevent cardiovascular complications. It is prescribed by physicians as part of a broader treatment plan that may include lifestyle changes and other antihypertensive agents.

Betaxolol selectively blocks β1‑adrenergic receptors in the heart, preventing catecholamines from stimulating these receptors. This leads to a slower heart rate, reduced contractile force, and lower renin release from the kidneys, collectively decreasing cardiac output and systemic vascular resistance, which lowers arterial blood pressure and myocardial oxygen demand.

The dosage of Kerlone is individualized by the prescribing clinician based on the patient’s blood pressure, heart rate, renal function, and overall clinical condition. The prescriber determines the appropriate strength, frequency, and titration schedule, and patients should follow the written prescription without alteration.

The safety of betaxolol hydrochloride during pregnancy and lactation has not been definitively established, and it is classified as pregnancy category unknown. Healthcare providers should weigh potential benefits against possible risks, and it is generally recommended to avoid use unless clearly needed. Breastfeeding mothers should consult their physician before use.

To request Kerlone, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies, and procurement teams worldwide, and will verify trade or institutional credentials. The sales team then provides pricing, availability, shipping details (including any cold‑chain requirements), and assists with import documentation.

Compared with non‑selective β‑blockers, betaxolol offers greater β1 selectivity, which may reduce the risk of bronchospasm in patients with mild respiratory disease. Relative to calcium channel blockers, it primarily lowers heart rate rather than causing vasodilation. Choice of therapy depends on individual patient profile, comorbidities, and physician judgment.

Kerlone should be stored below 25 °C in a dry environment. Keep the tablets in the original container, protect them from moisture and direct sunlight, and ensure the packaging remains sealed until use. Do not refrigerate or freeze the product, and keep it out of reach of children.

Kerlone is taken orally, usually with or without food, as directed by the prescribing physician. The tablet should be swallowed whole with a glass of water and not chewed or crushed, unless the prescriber advises otherwise. Consistent timing each day helps maintain stable blood levels.

The most serious adverse events include severe bradycardia, heart block, marked hypotension, and allergic reactions such as anaphylaxis. Patients experiencing faintness, very slow pulse, chest pain, or signs of an allergic response should seek immediate medical attention. Regular monitoring can help detect these risks early.

Kerlone is contraindicated in patients with severe bradycardia, second‑ or third‑degree atrioventricular block, cardiogenic shock, or overt heart failure. It should also be avoided in individuals with known hypersensitivity to betaxolol or any component of the formulation. Clinicians must assess each patient’s medical history before initiating therapy.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.