Product image of Kerlone (Betaxolol Hydrochloride) supplied by GNH India

Kerlone

Active Ingredient:
Betaxolol Hydrochloride
Origin:
EU

Kerlone (Betaxolol Hydrochloride)

Betaxolol Hydrochloride, the active ingredient in Kerlone, is a beta blocker presented as an oral tablet for systemic use. It is employed to lower elevated blood pressure by reducing heart rate and cardiac output, primarily in adult patients with hypertension.

GNH India supplies Kerlone as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides reliable sourcing for regulated markets. Its distribution network ensures timely delivery and compliance with local regulatory requirements.

Manufacturer / TM Owner

Cheplapharm Arzneimittel Gmbh

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Indications & Clinical Uses

Betaxolol Hydrochloride is a selective β1‑adrenergic blocker used in the management of hypertension and related cardiovascular conditions.

  • Hypertension: lowers systolic and diastolic blood pressure, reducing cardiovascular risk.
  • Stable angina: decreases myocardial oxygen demand by slowing heart rate.
  • Post‑myocardial infarction prophylaxis: helps prevent recurrent ischemic events by controlling heart rate and blood pressure.

How It Works

  • Betaxolol Hydrochloride selectively antagonizes β1‑adrenergic receptors in cardiac tissue, inhibiting the effects of endogenous catecholamines. This reduces heart rate, myocardial contractility, and renin release, leading to decreased cardiac output and peripheral vascular resistance, which together lower systemic blood pressure.

Side Effects

Betaxolol Hydrochloride may cause a range of adverse reactions, most of which are dose‑related and reversible upon discontinuation.

Common Side Effects

  • Fatigue: feeling of reduced energy or tiredness.
  • Dizziness: light‑headed sensation, especially on standing.
  • Bradycardia: slower than normal heart rate.
  • Cold extremities: reduced peripheral circulation.
  • Headache: mild to moderate pain in the head.
  • Nausea: upset stomach or urge to vomit.

Serious or Rare Side Effects

  • Severe bradycardia: markedly low heart rate requiring medical attention.
  • Heart block: impaired electrical conduction in the heart.
  • Bronchospasm: narrowing of airways, especially in patients with asthma.
  • Hypotension: dangerously low blood pressure.
  • Allergic reactions: rash, itching, or swelling.
  • Depression: mood changes or persistent sadness.

Precautions & Warnings

Before initiating therapy with Betaxolol Hydrochloride, clinicians should consider several safety measures.

  • Blood pressure monitoring: ensure adequate control and avoid excessive hypotension.
  • Heart rate assessment: watch for bradycardia, especially in patients with conduction disorders.
  • Asthma caution: use carefully in patients with reactive airway disease.
  • Discontinuation: avoid abrupt withdrawal to prevent rebound hypertension.
  • Renal impairment: adjust dose in patients with reduced kidney function.
  • Store at room temperature: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Betaxolol Hydrochloride can interact with other medicines, altering its efficacy or safety profile.

Major Interactions (Avoid)

  • Calcium channel blockers (e.g., verapamil): may cause profound bradycardia.
  • Other antihypertensives (e.g., ACE inhibitors): increase risk of hypotension.
  • Clonidine: concurrent use can lead to severe blood pressure drops.

Moderate Interactions (Monitor Closely)

  • NSAIDs: may reduce antihypertensive effect.
  • Diuretics: can exacerbate electrolyte imbalances.
  • Insulin or oral hypoglycemics: beta‑blockade may mask hypoglycemia symptoms.
  • Antidepressants (SSRIs): may enhance bradycardic response.

Frequently Asked Questions

Kerlone contains Betaxolol Hydrochloride, a beta‑blocker prescribed to lower high blood pressure (hypertension) and to manage certain cardiac conditions such as stable angina and post‑myocardial infarction prophylaxis.

Betaxolol Hydrochloride selectively blocks β1‑adrenergic receptors in the heart, reducing the effects of adrenaline. This slows the heart rate, decreases contractility, and lowers renin release, which together reduce cardiac output and systemic blood pressure.

The appropriate dose of Kerlone is determined by a qualified prescriber based on the patient’s clinical condition, response to therapy, and any co‑existing medical issues. Patients should follow the prescribing information provided by their healthcare professional.

Safety of Betaxolol Hydrochloride in pregnancy or while breastfeeding has not been definitively established. Healthcare providers should weigh potential benefits against possible risks and consider alternative treatments when appropriate.

To request Kerlone, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Kerlone (Betaxolol) is a cardio‑selective β1‑blocker, offering heart‑rate control with fewer respiratory side effects compared with non‑selective beta‑blockers. It is often chosen when a patient requires blood‑pressure reduction without significant bronchospasm risk, but the choice depends on individual patient profiles and comorbidities.

Kerlone should be stored at room temperature, below 25 °C, in its original packaging. Keep the product away from moisture, direct sunlight, and excessive heat to maintain its stability.

Kerlone is taken orally, usually with or without food, as directed by the prescribing clinician. The tablet should be swallowed whole with a glass of water and not chewed or crushed unless specifically instructed.

Serious risks include severe bradycardia, heart block, marked hypotension, bronchospasm in susceptible individuals, and rare allergic reactions. Patients should seek immediate medical attention if they experience fainting, rapid weight gain, severe shortness of breath, or signs of an allergic response.

Kerlone is contraindicated in patients with known hypersensitivity to Betaxolol or other beta‑blockers, those with severe bradycardia, second‑ or third‑degree heart block, uncompensated heart failure, or severe asthma/COPD where β‑blockade could worsen airway obstruction.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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