Product image of Kerlone (Betaxolol Hydrochloride) supplied by GNH India

Kerlone

Active Ingredient:
Betaxolol Hydrochloride
Origin:
EU

Kerlone (Betaxolol Hydrochloride)

Betaxolol Hydrochloride, the active ingredient in Kerlone, is a selective β1‑adrenergic antagonist presented as an oral tablet for oral administration. It lowers elevated blood pressure and relieves chest pain by reducing heart rate and myocardial contractility, making it appropriate for adult patients with hypertension or angina pectoris.

GNH India supplies Kerlone as a licensed, GDP‑compliant international pharmaceutical supplier, providing the product to hospitals, pharmacies and clinics worldwide with consistent quality and regulatory compliance.

Manufacturer / TM Owner

Lavipharm Hellas Ae

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Indications & Clinical Uses

Betaxolol Hydrochloride is a selective β1‑blocker used in cardiovascular conditions.

  • Hypertension: lowers systolic and diastolic blood pressure in patients with essential hypertension.
  • Angina pectoris: reduces myocardial oxygen demand and eases chest pain during exertion.
  • Stable angina: improves exercise tolerance by decreasing heart rate and contractility.

How It Works

  • Betaxolol Hydrochloride selectively blocks β1‑adrenergic receptors in cardiac tissue, inhibiting catecholamine‑induced stimulation. This results in decreased heart rate, reduced myocardial contractility, and lowered renin release from the kidneys, collectively contributing to a reduction in systemic blood pressure and cardiac workload.

Side Effects

Betaxolol Hydrochloride may cause adverse reactions that vary in frequency and severity.

Common Side Effects

  • Fatigue: feeling of tiredness or lack of energy.
  • Dizziness: light‑headed sensation, especially on standing.
  • Cold extremities: reduced blood flow to hands and feet.
  • Gastrointestinal discomfort: nausea or mild stomach upset.

Serious or Rare Side Effects

  • Severe bradycardia: markedly slow heart rate requiring medical attention.
  • Heart block: impairment of electrical conduction in the heart.
  • Bronchospasm: narrowing of airways, particularly in patients with reactive airway disease.

Precautions & Warnings

Before initiating Betaxolol Hydrochloride, consider the following precautions.

  • Monitor blood pressure: ensure adequate control and avoid hypotension.
  • Assess heart rate: check baseline rate and avoid use in severe bradycardia.
  • Use caution in asthma or COPD: β1‑selectivity may not fully prevent bronchoconstriction.
  • Avoid abrupt discontinuation: taper dose to prevent rebound hypertension.
  • Adjust dose in renal impairment: consider reduced clearance in patients with kidney dysfunction.
  • Store at room temperature: keep in the original pack, protect from moisture.

Avoid Interactions

Betaxolol Hydrochloride can interact with other medicines; awareness helps prevent adverse outcomes.

Major Interactions (Avoid)

  • Non‑selective beta‑blockers: additive bradycardia and hypotension.
  • Calcium channel blockers (verapamil, diltiazem): increased risk of AV block.
  • Class III anti‑arrhythmics (e.g., amiodarone): enhanced negative chronotropic effect.

Moderate Interactions (Monitor Closely)

  • Antidiabetic agents: beta‑blockers may mask hypoglycemia symptoms.
  • NSAIDs: may reduce antihypertensive efficacy of Betaxolol.

Frequently Asked Questions

Kerlone contains Betaxolol Hydrochloride, a selective β1‑blocker prescribed to lower high blood pressure and to relieve chest pain caused by angina pectoris in adult patients.

Betaxolol Hydrochloride blocks β1‑adrenergic receptors in the heart, decreasing heart rate, myocardial contractility, and renin release, which together reduce cardiac output and lower systemic blood pressure.

The appropriate dose of Kerlone is determined by the prescribing healthcare professional based on the individual’s medical condition, response to therapy, and any concomitant medications.

The safety of Betaxolol Hydrochloride in pregnancy and lactation has not been definitively established. It should only be used if the potential benefit justifies the potential risk to the fetus or infant, and under medical supervision.

To order Kerlone, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Kerlone (Betaxolol) is a selective β1‑blocker, offering heart‑rate control with fewer respiratory side effects than non‑selective beta‑blockers. Compared with ACE inhibitors or calcium channel blockers, it primarily reduces cardiac output rather than vascular resistance, making it useful when a heart‑rate‑lowering effect is desired.

Store Kerlone at room temperature, below 25 °C, in the original packaging. Protect the tablets from moisture and keep them out of reach of children.

Kerlone is taken orally, usually with or without food, as directed by the prescriber. Swallow the tablet whole with a glass of water; do not crush or chew unless specifically instructed.

Serious risks include severe bradycardia, heart block, and bronchospasm, especially in patients with pre‑existing cardiac conduction disorders or reactive airway disease. Prompt medical attention is required if symptoms such as fainting, extreme fatigue, or breathing difficulty occur.

Kerlone should be avoided in patients with severe bradycardia, second‑ or third‑degree heart block, uncompensated heart failure, or uncontrolled asthma/COPD, unless the prescriber determines that the benefits outweigh the risks.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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