Product image of Ketamin Abcur (Ketamine Hydrochloride) supplied by GNH India

Ketamin Abcur

Active Ingredient:
Ketamine Hydrochloride
Origin:
EU

Ketamin Abcur (Ketamine Hydrochloride)

Ketamine, the active ingredient in Ketamin Abcur, is a NMDA receptor antagonist presented as an injectable solution for intramuscular and intravenous use. It provides dissociative anesthesia and analgesia for patients requiring rapid induction, procedural sedation, or pain control.

GNH India supplies Ketamin Abcur as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals worldwide.

Manufacturer / TM Owner

Abcur Ab

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Indications & Clinical Uses

Ketamine is used in clinical settings that require rapid, controllable anesthesia or analgesia. It acts on the central nervous system to produce dissociative anesthesia.

  • Induction of anesthesia: enables quick loss of consciousness for surgical procedures.
  • Analgesia: provides potent pain relief during trauma care or postoperative periods.
  • Sedation: facilitates procedural sedation for diagnostic or therapeutic interventions.

How It Works

  • Ketamine acts as a non‑competitive antagonist at the N‑methyl‑D‑aspartate (NMDA) receptor, blocking excitatory glutamate transmission. This inhibition reduces neuronal firing in the CNS, producing dissociative anesthesia, analgesia, and sedation while preserving airway reflexes and cardiovascular stability.

Side Effects

Ketamine may cause a range of adverse reactions that vary in frequency and severity.

Common Side Effects

  • Hypertension: transient increase in blood pressure.
  • Tachycardia: elevated heart rate.
  • Nausea: feeling of sickness or urge to vomit.
  • Vomiting: expulsion of stomach contents.
  • Salivation: increased oral secretions.
  • Visual disturbances: blurred or altered vision.

Serious or Rare Side Effects

  • Respiratory depression: reduced breathing effort.
  • Laryngospasm: involuntary closure of the vocal cords.
  • Emergence phenomena: vivid dreams or agitation on recovery.
  • Hepatotoxicity: liver enzyme elevations.
  • Allergic reaction: rash, itching, or anaphylaxis.
  • Urinary tract toxicity: cystitis with prolonged use.

Precautions & Warnings

Ketamine requires careful patient assessment and monitoring to minimize risks.

  • Cardiovascular monitoring: observe blood pressure and heart rate during administration.
  • Airway management: be prepared for airway support if respiratory depression occurs.
  • Psychiatric evaluation: consider risk of emergence phenomena in patients with psychosis.
  • Drug interactions: review concomitant medications that affect CNS or cardiovascular function.
  • Storage: Store below 25°C: keep in original container, protect from light and moisture.

Avoid Interactions

Ketamine can interact with other agents that influence the central nervous system or cardiovascular system.

Major Interactions (Avoid)

  • CNS depressants: may potentiate respiratory depression.
  • Sympathomimetic drugs: can exacerbate hypertension and tachycardia.

Moderate Interactions (Monitor Closely)

  • MAO inhibitors: may increase risk of hypertensive crisis.
  • Benzodiazepines: may reduce analgesic efficacy.
  • Anticholinergics: may worsen salivation or airway secretions.

Frequently Asked Questions

Ketamin Abcur contains ketamine hydrochloride and is used by healthcare professionals for induction of anesthesia, procedural analgesia, and sedation in a variety of clinical settings such as surgery, emergency care, and diagnostic procedures.

Ketamine blocks NMDA receptors in the central nervous system, reducing excitatory neurotransmission. This produces dissociative anesthesia, analgesia, and sedation while typically preserving airway reflexes and cardiovascular stability.

The dose of Ketamin Abcur is determined by the prescribing clinician based on the patient’s age, weight, clinical condition, and route of administration. Only a qualified healthcare professional should set the appropriate dosing regimen.

Safety data for ketamine in pregnancy and lactation are limited. The drug should be used only if the potential benefit justifies any potential risk to the fetus or infant, and decisions should be made by the treating physician.

To order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and import documentation.

Ketamine is unique among anesthetics because it provides dissociative anesthesia while maintaining airway reflexes and cardiovascular stability, unlike many agents that cause respiratory depression. It is often chosen when hemodynamic preservation is important or when a rapid onset is needed.

Ketamin Abcur should be stored below 25 °C, in its original packaging, protected from light and moisture. Do not freeze the product, and keep it out of reach of children.

Ketamin Abcur is supplied as an injectable solution and can be given intravenously or intramuscularly by a qualified healthcare professional. Administration technique, rate, and monitoring are determined by the clinical protocol and patient needs.

Serious risks include respiratory depression, laryngospasm, severe hypertension or tachycardia, emergence phenomena such as agitation or vivid dreams, and rare urinary tract toxicity with prolonged use. Immediate medical attention is required if any of these occur.

Ketamin Abcur is contraindicated in patients with known hypersensitivity to ketamine or its excipients, and should be used with caution in individuals with uncontrolled hypertension, severe cardiovascular disease, or a history of psychosis. The prescribing clinician decides suitability.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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