Product image of Ketamine Renaudin (Ketamine Hydrochloride) supplied by GNH India

Ketamine Renaudin

Active Ingredient:
Ketamine Hydrochloride
Origin:
EU

Ketamine Renaudin (Ketamine Hydrochloride)

Ketamine, the active ingredient in Ketamine Renaudin, is a dissociative anesthetic presented as a sterile injectable solution for intramuscular, intravenous use. It is employed to induce and maintain anesthesia and to provide analgesia for acute pain, and it is sometimes used off‑label for treatment‑resistant depression.

GNH India supplies Ketamine Renaudin as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Laboratoire Renaudin

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Ketamine is a dissociative anesthetic used across several clinical pathways.

  • Induction and maintenance of anesthesia: provides rapid, controllable dissociative anesthesia for surgical procedures.
  • Analgesia for acute pain: delivers potent analgesic effect in peri‑operative and trauma settings.
  • Off‑label use for treatment‑resistant depression: may be administered under specialist supervision to alleviate depressive symptoms.

How It Works

  • Ketamine acts as a non‑competitive antagonist at the N‑methyl‑D‑aspartate (NMDA) receptor, reducing excitatory neurotransmission. By blocking the NMDA‑mediated calcium influx, it disrupts synaptic plasticity, leading to dissociative anesthesia and analgesia. Additional actions at opioid receptors, monoaminergic pathways, and voltage‑gated calcium channels contribute to its analgesic and antidepressant effects.

Side Effects

Ketamine can produce a range of adverse reactions that vary in frequency and severity.

Common Side Effects

  • Hypertension: transient increase in blood pressure.
  • Tachycardia: elevated heart rate during and shortly after administration.
  • Nausea or vomiting: gastrointestinal upset common after induction.
  • Emergence phenomena: vivid dreams, hallucinations, or dysphoria during recovery.

Serious or Rare Side Effects

  • Respiratory depression: reduced breathing effort requiring airway support.
  • Laryngospasm: sudden vocal cord closure that may obstruct airway.
  • Neurotoxicity: rare reports of cortical damage with prolonged high‑dose exposure.

Precautions & Warnings

Ketamine requires careful patient assessment and monitoring.

  • Cardiovascular assessment: evaluate baseline blood pressure and heart rate before use.
  • Psychiatric history: consider risk of emergence phenomena in patients with psychosis.
  • Drug interactions: avoid concurrent use with other NMDA antagonists or potent CNS depressants.
  • Pregnancy and lactation: use only if benefits outweigh potential risks, as safety data are limited.
  • Storage: Store at below 25°C: keep in original container, protect from light and moisture.

Avoid Interactions

Ketamine may interact with several drug classes, necessitating vigilance.

Major Interactions (Avoid)

  • Other NMDA antagonists (e.g., dextromethorphan): additive CNS effects.
  • Central nervous system depressants (e.g., benzodiazepines, opioids): heightened respiratory depression.

Moderate Interactions (Monitor Closely)

  • Sympathomimetic agents (e.g., epinephrine): may exacerbate hypertension.
  • MAO inhibitors: potential for unpredictable hemodynamic changes.
  • Anticholinergic drugs: may increase risk of urinary retention.

Frequently Asked Questions

Ketamine Renaudin is used primarily for the induction and maintenance of general anesthesia and for providing analgesia in acute pain situations. In some specialist settings it may also be employed off‑label for patients with treatment‑resistant depression, always under strict medical supervision.

Ketamine works by blocking the NMDA receptor, a key component of excitatory neurotransmission in the central nervous system. This antagonism reduces calcium influx, leading to dissociative anesthesia and analgesia. Additional actions at opioid receptors and monoamine pathways contribute to its broader clinical effects.

The dose of Ketamine Renaudin is determined by the prescribing clinician based on the specific indication, patient characteristics, and route of administration. Healthcare professionals calculate the appropriate amount according to established clinical guidelines and individual patient needs.

Safety data for ketamine in pregnancy and lactation are limited. It should only be used when the potential therapeutic benefit justifies any potential risk to the fetus or infant, and this decision must be made by a qualified healthcare provider.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if needed), and import documentation.

Ketamine is distinct from many inhalational or opioid‑based anesthetics because it provides both anesthesia and analgesia while preserving airway reflexes and cardiovascular stability. Compared with agents such as propofol, ketamine has a higher incidence of emergence phenomena but offers advantages in patients at risk of hypotension.

Ketamine Renaudin should be stored at temperatures below 25 °C, in its original packaging, protected from light and moisture. Maintaining these conditions helps preserve potency and sterility throughout its shelf life.

Ketamine Renaudin is supplied as a sterile injectable solution and can be given intravenously or intramuscularly by a qualified healthcare professional. The route, rate, and total dose are selected according to the clinical situation and the patient’s response.

The most serious risks include respiratory depression, laryngospasm, and rare neurotoxic effects with high‑dose or prolonged exposure. Prompt recognition and management of airway compromise and hemodynamic changes are essential during administration.

Ketamine Renaudin is contraindicated in patients with known hypersensitivity to ketamine or its excipients, those with uncontrolled hypertension, severe coronary artery disease, or a history of psychosis where emergence phenomena could be hazardous. Clinical judgment should guide exclusion.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Related Products

Other formulations containing Ketamine Hydrochloride

A

A
A

A
A

A
A

A

Browse all products →

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Regulatory recognitions

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.

SGS GSDP Certification

GSDP Compliant from SGS

URS ISO 9001

URS ISO 9001 Certification

FDA Maharashtra

Licensed by FDA Maharashtra

IEC License DGFT

IEC License issued by DGFT