Ketesse (Dexketoprofen)

Dexketoprofen works by non‑selectively inhibiting the cyclooxygenase‑1 and cyclooxygenase‑2 enzymes. This blocks the conversion of arachidonic acid into prostaglandins, which are key mediators of inflammation, pain, and fever. Reducing prostaglandin levels diminishes peripheral sensitisation of nerve endings, providing analgesic and anti‑inflammatory effects.

The appropriate dose of Ketesse is determined by the prescribing healthcare professional based on the individual’s medical condition, severity of pain, age, renal and hepatic function, and any concomitant medications. Patients should follow the prescriber’s instructions and not adjust the dose on their own.

Safety of dexketoprofen in pregnancy and lactation has not been definitively established. It is generally advised to avoid use during the first trimester and to limit exposure throughout pregnancy unless the potential benefit justifies the risk. Breastfeeding mothers should consult a physician, as the drug may be excreted in milk.

To order Ketesse, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, and will request verification of trade or institutional credentials. After confirmation, the team provides pricing, availability, shipping details (including any cold‑chain requirements) and assists with import documentation.

Ketesse (dexketoprofen) is the S‑enantiomer of ketoprofen and generally offers a faster onset of analgesia compared with many traditional NSAIDs like ibuprofen. Its potency allows effective pain control at lower doses, but the safety profile regarding gastrointestinal, renal and cardiovascular risks remains similar to other non‑selective NSAIDs.

Ketesse tablets should be stored at ambient temperature, preferably below 25 °C. Keep them in the original packaging to protect from moisture and light. Do not store in bathrooms or near heat sources, and keep out of reach of children.

Ketesse is formulated for oral administration. The tablet should be swallowed whole with a glass of water, preferably with food or after a meal to reduce potential gastrointestinal irritation, unless otherwise directed by a healthcare professional.

Serious risks include gastrointestinal ulceration or bleeding, especially in patients with a history of ulcers or who use anticoagulants; renal impairment that can progress to acute kidney injury; severe allergic reactions such as anaphylaxis; and cardiovascular events like myocardial infarction or stroke in high‑risk individuals.

Ketesse should be avoided in patients with known hypersensitivity to dexketoprofen or other NSAIDs, those with active gastrointestinal bleeding or ulcer disease, severe renal or hepatic impairment, uncontrolled hypertension, and in the third trimester of pregnancy. It is also contraindicated in individuals receiving other non‑selective NSAIDs or COX‑2 inhibitors without medical supervision.