Product image of Keto (Ketoprofen) supplied by GNH India

Keto

Active Ingredient:
Ketoprofen
Origin:
EU

Keto (Ketoprofen)

Ketoprofen, the active ingredient in Keto, is a nonsteroidal anti-inflammatory drug presented as an oral formulation for systemic use. It is employed to relieve mild to moderate pain and to reduce inflammation in conditions such as rheumatoid arthritis, osteoarthritis, and musculoskeletal disorders.

GNH India supplies Keto as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides regulatory documentation for each batch. This enables reliable sourcing for global healthcare providers seeking consistent product performance.

Manufacturer / TM Owner

Vitabalans Oy

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Indications & Clinical Uses

  • Ketoprofen is an NSAID that reduces inflammation and pain by inhibiting cyclooxygenase enzymes.
  • Rheumatoid arthritis: alleviates joint inflammation and pain, improving mobility.
  • Osteoarthritis: reduces cartilage‑related discomfort and stiffness.
  • Musculoskeletal pain: eases strain‑related aches and facilitates functional recovery.
  • Acute postoperative pain: provides short‑term analgesia after surgical procedures.

How It Works

  • Ketoprofen exerts its effect by non‑selectively inhibiting cyclooxygenase‑1 (COX‑1) and cyclooxygenase‑2 (COX‑2) enzymes, which blocks the conversion of arachidonic acid to prostaglandins. The resulting decrease in prostaglandin synthesis diminishes inflammation, pain signaling, and fever responses at the site of tissue injury.

Side Effects

Ketoprofen may cause a range of adverse reactions, from mild to severe.

Common Side Effects

  • Nausea or upset stomach.
  • Dyspepsia or heartburn.
  • Headache.
  • Dizziness or light‑headedness.
  • Mild skin rash.
  • Elevated liver enzymes.

Serious or Rare Side Effects

  • Gastrointestinal bleeding or ulcer perforation.
  • Severe renal impairment or failure.
  • Anaphylactic or severe hypersensitivity reactions.
  • Stevens‑Johnson syndrome or toxic epidermal necrolysis.
  • Hepatotoxicity with jaundice.
  • Cardiovascular events such as myocardial infarction or stroke.

Precautions & Warnings

  • When using Ketoprofen, consider the following safety measures.
  • Assess gastrointestinal risk: evaluate history of ulcers or bleeding before initiating therapy.
  • Monitor renal function: check creatinine and electrolytes in patients with kidney disease.
  • Use lowest effective dose: limit exposure to reduce adverse event likelihood.
  • Avoid in known hypersensitivity: discontinue if rash, swelling, or breathing difficulty occurs.
  • Caution in cardiovascular disease: weigh benefits against potential thrombotic risk.
  • Store at room temperature: keep in the original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Ketoprofen can interact with several drug classes; awareness helps prevent complications.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased risk of serious bleeding.
  • Other NSAIDs or aspirin: additive gastrointestinal toxicity.
  • Corticosteroids: heightened ulcer risk.

Moderate Interactions (Monitor Closely)

  • Lithium: NSAIDs may raise lithium serum levels.
  • ACE inhibitors or ARBs: possible reduction in renal function, especially in volume‑depleted patients.

Frequently Asked Questions

Keto contains ketoprofen, an NSAID indicated for mild to moderate pain and inflammation. It is commonly prescribed for rheumatoid arthritis, osteoarthritis, musculoskeletal pain, and short‑term postoperative discomfort, helping to reduce swelling and improve functional ability.

Ketoprofen blocks the activity of both COX‑1 and COX‑2 enzymes, which are essential for converting arachidonic acid into prostaglandins. By lowering prostaglandin levels, the drug diminishes the inflammatory response and the transmission of pain signals at the affected site.

The appropriate dose of Keto is determined by the prescribing healthcare professional based on the individual’s condition, age, renal and hepatic function, and other medications. Patients should follow the prescriber’s instructions and not adjust the dose on their own.

Safety of ketoprofen in pregnancy and lactation has not been definitively established. It should only be used if the potential benefit justifies the possible risk to the fetus or infant, and this decision must be made by a qualified healthcare provider.

To request Keto, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Ketoprofen and ibuprofen belong to the same NSAID class but differ in potency and pharmacokinetics. Ketoprofen generally offers stronger analgesic and anti‑inflammatory effects at comparable doses, while ibuprofen may have a slightly lower risk of gastrointestinal irritation for some patients. Choice depends on clinical response and individual tolerance.

Keto should be stored at room temperature, preferably below 25 °C. Keep the product in its original packaging, protect it from moisture and direct sunlight, and ensure the container is tightly closed to maintain stability.

Keto is taken orally, usually with a full glass of water. It can be taken with or without food, but taking it with meals may reduce stomach upset. Patients should swallow the tablet whole and avoid crushing or chewing unless instructed otherwise.

The most serious risks include gastrointestinal bleeding or ulcer perforation, severe renal impairment, hepatotoxicity, and rare but life‑threatening skin reactions such as Stevens‑Johnson syndrome. Patients should seek immediate medical attention if they notice signs of bleeding, sudden kidney problems, or severe skin changes.

Ketoprofen should be avoided in individuals with known hypersensitivity to ketoprofen or other NSAIDs, active peptic ulcer disease, severe heart failure, uncontrolled hypertension, or significant renal or hepatic impairment. It is also contraindicated in patients who are currently taking anticoagulants, other NSAIDs, or corticosteroids without close medical supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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