Product image of Ketoconazol Dr.Max (Ketoconazole) supplied by GNH India

Ketoconazol Dr.Max

Active Ingredient:
Ketoconazole
Origin:
EU

Ketoconazol Dr.Max (Ketoconazole)

Ketoconazole, the active ingredient in Ketoconazol Dr.Max, is an azole antifungal presented as a topical formulation for skin use. It treats fungal skin infections such as dermatophytosis, seborrheic dermatitis, and tinea versicolor in adults and children. It is indicated for both mild and moderate infections and is applied directly to the affected area.

GNH India supplies Ketoconazol Dr.Max as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides regulatory documentation for global distribution.

Manufacturer / TM Owner

Dr. Max Pharma S.R.O.

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Indications & Clinical Uses

  • Ketoconazole is an azole antifungal used to treat superficial fungal infections of the skin.
  • Dermatophytosis: Inhibits the dermatophyte fungi responsible for ringworm and athlete’s foot, leading to reduction of itching, redness, and scaling.
  • Seborrheic dermatitis: Controls Malassezia yeast overgrowth, decreasing scalp redness, flaking, and facial irritation.
  • Tinea versicolor: Clears pigmentary changes by eradicating the causative yeast and preventing recurrence.

How It Works

  • Ketoconazole blocks the fungal enzyme lanosterol 14α‑demethylase, a key step in ergosterol synthesis. By preventing ergosterol formation, the drug disrupts the integrity of the fungal cell membrane, leading to increased permeability and ultimately cell death. This targeted inhibition limits fungal growth on the skin surface without affecting human cells.

Side Effects

Ketoconazole is generally well tolerated when applied topically, but local and systemic reactions can occur.

Common Side Effects

  • Local irritation or burning sensation at the application site
  • Pruritus (itching)
  • Dryness or peeling of the skin
  • Mild erythema (redness)
  • Contact dermatitis in sensitive individuals

Serious or Rare Side Effects

  • Severe allergic reaction such as angioedema or anaphylaxis
  • Extensive contact dermatitis with blistering
  • Photosensitivity leading to exaggerated sunburn
  • Systemic absorption causing hepatic enzyme elevation (rare)
  • Secondary bacterial infection of the treated area

Precautions & Warnings

  • Before using Ketoconazol Dr.Max, consider the following safety measures.
  • Avoid use on broken skin: increased systemic absorption may occur.
  • Do not apply to eyes, mucous membranes, or genital areas: can cause irritation.
  • Limit duration of therapy: prolonged use may promote resistance.
  • Discontinue if severe irritation or allergic reaction develops: seek medical advice.
  • Store at ambient temperature: keep in the original container, protect from moisture and light.

Avoid Interactions

Ketoconazol may interact with other topical or systemic agents; awareness helps avoid adverse outcomes.

Major Interactions (Avoid)

  • Concurrent use of oral ketoconazole: risk of cumulative systemic exposure.
  • Co‑application with other azole‑containing topical antifungals: may increase local irritation.
  • Simultaneous use of corticosteroid creams on the same area: can mask infection signs.

Moderate Interactions (Monitor Closely)

  • Use with topical retinoids: potential for heightened skin irritation.
  • Concurrent use of photosensitizing agents (e.g., tetracyclines): may enhance sun sensitivity.
  • Application together with harsh chemical peels: could exacerbate dermatitis.

Frequently Asked Questions

Ketoconazol Dr.Max is a topical azole antifungal indicated for superficial fungal skin infections such as dermatophytosis (ringworm and athlete’s foot), seborrheic dermatitis, and tinea versicolor. It works by eliminating the fungi that cause these conditions, helping to relieve itching, redness, and scaling.

Ketoconazole inhibits the fungal enzyme lanosterol 14α‑demethylase, which is essential for ergosterol synthesis. Ergosterol is a critical component of the fungal cell membrane. By blocking its production, the drug disrupts membrane integrity, leading to increased permeability and fungal cell death.

The dosage and frequency of Ketoconazol Dr.Max are determined by the prescribing healthcare professional based on the specific infection, its severity, and patient factors. Patients should follow the prescriber’s instructions and the product label for proper application.

Safety data for topical ketoconazole in pregnancy and lactation are limited. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss potential risks with their healthcare provider before using the product.

To request Ketoconazol Dr.Max, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies, and procurement teams worldwide, and will verify trade or institutional credentials before providing pricing, availability, shipping details, and any required import documentation.

Ketoconazol belongs to the azole class, offering broad‑spectrum activity against dermatophytes and yeasts. Compared with allylamine agents such as terbinafine, ketoconazole may be preferred for infections involving Malassezia species (e.g., seborrheic dermatitis). Choice of therapy depends on the pathogen, site of infection, and patient tolerance.

Ketoconazol Dr.Max should be stored at ambient temperature, below 25 °C, in its original packaging. Keep the container tightly closed, protect it from moisture and direct sunlight, and keep it out of reach of children.

Apply a thin layer of the product to the affected skin area once or twice daily, as directed by the prescriber. Gently rub it in until it disappears, and wash hands before and after application. Avoid covering the treated area with occlusive dressings unless instructed.

Serious risks, although rare, include severe allergic reactions such as angioedema or anaphylaxis, extensive contact dermatitis, and photosensitivity. Systemic absorption can rarely affect liver enzymes. Patients should stop use and seek immediate medical attention if they experience swelling, difficulty breathing, or intense skin reactions.

Ketoconazol Dr.Max should be avoided in individuals with a known hypersensitivity to ketoconazole or any azole antifungal. It is also contraindicated on severely damaged or broken skin, and in patients who have experienced severe reactions to other topical antifungal preparations.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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