Product image of Ketoconazol Fiterman (Ketoconazole) supplied by GNH India

Ketoconazol Fiterman

Active Ingredient:
Ketoconazole
Origin:
EU

Ketoconazol Fiterman (Ketoconazole)

Ketoconazole, the active ingredient in Ketoconazol Fiterman, is an azole antifungal presented as a topical formulation for cutaneous use. It is employed to treat common fungal skin infections and related dermatoses in patients of various ages.
GNH India supplies Ketoconazol Fiterman as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Fiterman Pharma S.R.L.

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Indications & Clinical Uses

Ketoconazole is an azole antifungal that interferes with fungal cell membrane synthesis, making it effective for several dermatological infections.

  • Tinea corporis: reduces fungal growth and clears the body rash.
  • Tinea cruris: alleviates itching and resolves the groin infection.
  • Seborrheic dermatitis: controls yeast‑related scalp and skin inflammation.
  • Pityriasis versicolor: eliminates the pigment‑changing yeast infection on the trunk.

How It Works

  • Ketoconazole inhibits the fungal enzyme lanosterol 14α‑demethylase, a key step in ergosterol synthesis. By blocking ergosterol production, the drug disrupts the integrity of the fungal cell membrane, leading to increased permeability and ultimately fungal cell death or growth inhibition.

Side Effects

Topical ketoconazole may cause local skin reactions, ranging from mild irritation to rare severe hypersensitivity.

Common Side Effects

  • Burning sensation: transient discomfort at the application site.
  • Itching: mild pruritus during treatment.
  • Dryness: skin may become less moist.
  • Erythema: redness of the treated area.
  • Scaling: flaking of the skin surface.
  • Stinging: brief sharp sensation.

Serious or Rare Side Effects

  • Allergic contact dermatitis: widespread rash and swelling.
  • Severe skin reactions: such as Stevens‑Johnson syndrome.
  • Systemic absorption toxicity: rare hepatic effects.
  • Photosensitivity: increased sensitivity to sunlight.
  • Angioedema: swelling of deeper skin layers.
  • Bullous reactions: blister formation on the skin.

Precautions & Warnings

When using Ketoconazol Fiterman, observe the following safety measures.

  • Avoid application on broken or inflamed skin: may increase irritation.
  • Do not apply near eyes or mucous membranes: can cause severe irritation.
  • Use only as directed by a healthcare professional: follow prescribed frequency.
  • Monitor for signs of allergic reaction: discontinue if rash or swelling occurs.
  • Discontinue if severe irritation develops: seek medical advice.
  • Store at room temperature: keep in the original container, protect from moisture and heat.

Avoid Interactions

Ketoconazol Fiterman may interact with other agents applied to the skin or absorbed systemically.

Major Interactions (Avoid)

  • Concurrent systemic azole antifungals: risk of additive toxicity.
  • Topical corticosteroids: may mask irritation and delay detection of adverse reactions.

Moderate Interactions (Monitor Closely)

  • Alcohol‑based skin products: can increase local irritation.
  • Phototoxic agents: may heighten photosensitivity risk.
  • Other topical antifungals: assess for overlapping toxicity.

Frequently Asked Questions

Ketoconazol Fiterman is a topical azole antifungal indicated for the treatment of superficial fungal skin infections such as tinea corporis, tinea cruris, seborrheic dermatitis and pityriasis versicolor. It works by targeting the fungal cell membrane, helping to clear the infection and relieve associated symptoms.

Ketoconazole blocks the fungal enzyme lanosterol 14α‑demethylase, which is essential for synthesising ergosterol, a key component of the fungal cell membrane. Inhibiting this pathway compromises membrane integrity, leading to fungal cell death or inhibited growth, thereby resolving the infection.

The specific dosage and frequency of Ketoconazol Fiterman are determined by the prescribing healthcare professional based on the infection type, severity, patient age and skin condition. Patients should follow the prescriber’s instructions and the product label carefully.

Safety data for topical ketoconazole in pregnancy and lactation are limited. It should only be used if the potential benefit justifies any potential risk to the fetus or infant, and the decision should be made by a qualified healthcare provider.

To place an order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Ketoconazol belongs to the azole class, offering a broad spectrum against dermatophytes and yeasts. Compared with allylamine agents such as terbinafine, azoles have a different mechanism and may be preferred for conditions like seborrheic dermatitis where yeast overgrowth is prominent. Choice of therapy depends on infection type, patient factors and clinician judgment.

Ketoconazol Fiterman should be stored at room temperature, below 25 °C, in its original packaging. Keep the container tightly closed, protect it from moisture, direct sunlight and excessive heat to maintain product stability.

The cream or ointment is applied thinly to the affected skin area, usually twice daily, unless otherwise directed by a healthcare professional. Hands should be washed before and after application, and the treated area should be gently cleaned and dried prior to use.

Serious risks, though rare, include severe allergic reactions such as contact dermatitis, Stevens‑Johnson syndrome, and systemic toxicity from significant absorption leading to hepatic effects. Patients should discontinue use and seek immediate medical attention if they experience widespread rash, swelling, blistering or signs of liver dysfunction.

Individuals with a known hypersensitivity to ketoconazole, other azole antifungals, or any component of the formulation should avoid using the product. It is also contraindicated on extensive broken skin, mucous membranes and the ocular area.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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