Ketoconazol Korhispana (Ketoconazole)

Ketoconazole blocks the fungal enzyme lanosterol 14α‑demethylase, which is essential for producing ergosterol, a critical component of the fungal cell membrane. Inhibiting ergosterol synthesis compromises membrane integrity, leading to increased permeability and fungal cell death.

The specific dosage and frequency are determined by the prescribing healthcare professional based on the infection type, severity, and patient factors. Patients should follow the prescriber’s instructions and the product label for optimal results.

Safety data for topical ketoconazole in pregnancy and lactation are limited. Healthcare providers should evaluate the risk‑benefit ratio before prescribing to pregnant or nursing individuals, and use only if clearly needed.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Ketoconazole belongs to the azole class, offering broad‑spectrum activity against dermatophytes and yeasts. Compared with allylamine agents such as terbinafine, ketoconazole may be preferred for infections involving Malassezia species, while terbinafine is often chosen for nail infections. Choice depends on the pathogen, site of infection, and patient tolerance.

Store the product at ambient temperature, preferably below 25 °C. Keep it in the original packaging, protect it from moisture and direct sunlight, and ensure the container is tightly closed to maintain product stability.

Apply a thin layer of the cream or ointment to the affected skin area once or twice daily, as directed by the prescriber. Gently rub it in until fully absorbed, and wash hands before and after application to avoid accidental contact with eyes or mucous membranes.

Serious risks, though rare, include severe allergic reactions such as angioedema or anaphylaxis, extensive skin irritation or ulceration, and systemic effects like hepatotoxicity or hormonal disturbances. Patients should discontinue use and seek medical attention if they experience any of these symptoms.

Individuals with known hypersensitivity to ketoconazole or any component of the formulation should avoid using the product. It is also contraindicated on extensive broken skin, and caution is advised in patients with pre‑existing liver disease or those taking other hepatotoxic medications.