Ketoconazol Ratiopharm (Ketoconazole)

Ketoconazole belongs to the imidazole class of antifungals. It blocks the fungal enzyme lanosterol 14α‑demethylase, which is essential for synthesising ergosterol, a key component of fungal cell membranes. Without ergosterol, the membrane becomes defective, leading to increased permeability and fungal cell death.

The specific dosage and frequency are determined by the prescribing healthcare professional based on the type and severity of the infection, the patient’s age, and skin condition. Patients should follow the prescriber’s instructions and the product label, applying the recommended amount to the affected area as directed.

Safety data for topical ketoconazole during pregnancy and lactation are limited. It should only be used when the potential benefit to the mother outweighs any possible risk to the fetus or infant. Women who are pregnant, planning pregnancy, or breastfeeding should discuss use with their healthcare provider.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, and will request verification of trade or institutional credentials. After confirmation, the team provides pricing, availability, shipping details (including any cold‑chain requirements) and assists with import documentation.

Ketoconazole offers broad‑spectrum activity against dermatophytes, yeasts and some molds, making it effective for a range of skin infections. Compared with alternatives such as clotrimazole or terbinafine, ketoconazole may have a slightly higher risk of local irritation but provides comparable cure rates for many indications. Choice of agent often depends on clinician preference, local resistance patterns and patient tolerance.

Store the product at room temperature, preferably below 25 °C, in its original packaging. Keep the container tightly closed, protect it from moisture and direct sunlight, and keep it out of reach of children. Do not freeze or expose the cream to extreme temperatures, as this may affect its consistency and potency.

Apply a thin layer of the cream to the cleaned, dry skin area affected by the fungal infection. Gently rub it in until fully absorbed, usually twice daily or as directed by the prescriber. Wash hands after application, and avoid covering the treated area with occlusive dressings unless instructed, as this can increase systemic absorption.

Although rare, serious adverse reactions can occur. Watch for signs of severe allergic response such as extensive rash, swelling of the face or lips, difficulty breathing, or sudden onset of fever. Contact dermatitis that worsens despite discontinuation should also be reported. If any of these symptoms appear, stop using the product and seek immediate medical attention.

Individuals with a known hypersensitivity to ketoconazole, other imidazole antifungals, or any component of the formulation should avoid using the product. It should not be applied to broken, ulcerated or inflamed skin, and patients with severe liver disease should consult a physician before use due to potential systemic absorption.