Product image of Ketoconazole (Ketoconazole) 20 mg/g Cream supplied by GNH India

Ketoconazole (Ketoconazole)

Active Ingredient:
Ketoconazole (Ketoconazole)
Form:
Cream
Brand:
Ketoconazole
Origin:
US

Ketoconazole (Ketoconazole) (Cream) 20 mg/g

Ketoconazole, the active ingredient in Ketoconazole, is an imidazole antifungal presented as a 20 mg/g cream for topical use. It is used to treat fungal skin infections such as athlete's foot, jock itch, and ringworm. GNH India supplies Ketoconazole as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies, and clinics worldwide.

Ketoconazole cream is a topical antifungal medication used to treat various skin infections caused by fungi. It is effective in alleviating symptoms such as itching, redness, and scaling.

Strength

20 mg/g

Manufacturer / TM Owner

Teva Pharmaceuticals USA, Inc.

1
Pack/s
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Indications & Clinical Uses

Ketoconazole cream is an antifungal medication that acts on fungal infections of the skin. It is used to treat the following conditions:

  • Dermatophyte infections: Treats infections such as tinea corporis (ringworm), tinea cruris (jock itch), and tinea pedis (athlete's foot).
  • Seborrheic dermatitis: Helps manage symptoms of seborrheic dermatitis, a skin condition characterized by red, itchy, and flaky skin.
  • Pityriasis versicolor: Effective against the fungal infection that causes discolored patches on the skin.

How It Works

  • Ketoconazole works by inhibiting the fungal enzyme lanosterol 14α-demethylase, which disrupts the synthesis of ergosterol, a crucial component of fungal cell membranes. This disruption compromises the integrity of the cell membrane, leading to the death of the fungal cells.

Side Effects

Ketoconazole cream may cause side effects, although not everyone gets them. Common Side Effects:

  • Pruritus: Itching at the application site.
  • Irritation: Redness or discomfort where the cream is applied.
  • Burning sensation: A mild to moderate burning feeling after application.

Serious or Rare Side Effects

  • Allergic reactions: Rarely, some individuals may experience allergic reactions such as contact dermatitis.
  • Skin hypersensitivity: In rare cases, the skin may become overly sensitive to the cream or its components.

Precautions & Warnings

Ketoconazole cream should be used with caution and under the guidance of a healthcare professional. Apply to affected areas once daily: Follow the prescribed dosage and duration of treatment.

  • Avoid eyes and mucous membranes: Do not apply the cream to the eyes, nostrils, mouth, or vagina.
  • Pregnancy and lactation: The safety in pregnancy and lactation has not been established.
  • Hypersensitivity: Do not use if allergic to any of the ingredients.
  • Topical corticosteroids: Use with caution if transitioning from prolonged topical corticosteroid use.
  • Store at temperatures not exceeding 30°C: Keep the tube tightly closed and store in a dark location at room temperature.

Avoid Interactions

Ketoconazole cream may interact with other medications, although systemic interactions are rare due to its topical nature. Major Interactions (Avoid):

  • None significant for topical use.

Moderate Interactions (Monitor Closely)

  • Topical corticosteroids: To prevent a rebound effect, it is recommended to gradually withdraw steroid therapy over 2-3 weeks when transitioning from prolonged use.

Frequently Asked Questions

Ketoconazole cream is used to treat fungal skin infections such as athlete's foot (tinea pedis), jock itch (tinea cruris), and ringworm (tinea corporis). It is also effective against seborrheic dermatitis and pityriasis versicolor, helping to relieve symptoms like itching, redness, and scaling.

Ketoconazole works by inhibiting the fungal enzyme lanosterol 14α-demethylase, which disrupts the synthesis of ergosterol, a crucial component of fungal cell membranes. This disruption compromises the integrity of the cell membrane, leading to the death of the fungal cells.

The usual dosage of Ketoconazole cream is determined by a healthcare professional based on the specific condition being treated. It is generally applied to the affected areas once daily for a duration sufficient to clear the infection, which may range from 2 to 6 weeks depending on the condition.

The safety of Ketoconazole cream during pregnancy and breastfeeding has not been established. It is recommended to consult a healthcare professional before using this medication if you are pregnant or breastfeeding.

To order Ketoconazole cream from GNH India, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India supplies hospitals, pharmacies, and procurement teams across international markets and will ask the buyer to confirm trade or institutional credentials. The team will then reply with pricing, availability, shipping, and the import paperwork.

Ketoconazole is an effective topical antifungal medication that is often compared to other treatments like clotrimazole and miconazole. It is particularly useful for dermatophyte infections and seborrheic dermatitis. The choice of treatment depends on the specific condition, the patient's response, and the healthcare professional's recommendation.

Ketoconazole cream should be stored at temperatures not exceeding 30°C. Keep the tube tightly closed and store in a dark location at room temperature. Do not keep the product in cold temperatures or direct light.

Ketoconazole cream should be applied to the affected areas once daily. Before application, wash and completely dry the affected area. After application, the afflicted area should not be covered by bandages or dressings unless otherwise indicated by a healthcare professional. The afflicted area should not be submerged in water for 3 hours after application.

The most serious risks associated with Ketoconazole cream include allergic reactions and skin hypersensitivity. Rarely, some individuals may experience contact dermatitis. If any severe side effects occur, discontinue use and consult a healthcare professional immediately.

Ketoconazole cream should not be used by individuals who have shown hypersensitivity to any of its ingredients. It is also not recommended for use in the eyes, nostrils, mouth, or vagina. Always consult a healthcare professional before using this medication.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

References

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