Product image of Ketoflix (Ketoprofen Lysine) supplied by GNH India

Ketoflix

Active Ingredient:
Ketoprofen Lysine
Origin:
EU

Ketoflix (Ketoprofen Lysine)

Ketoprofen lysine, the active ingredient in Ketoflix, is a non‑steroidal anti‑inflammatory drug (NSAID) presented as an oral tablet for systemic use. It reduces pain and inflammation in conditions such as mild to moderate acute pain, osteoarthritis, rheumatoid arthritis, musculoskeletal injuries, and dysmenorrhea, providing symptomatic relief for adult patients.

GNH India supplies Ketoflix as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, ensuring quality and regulatory conformity across EU and global markets.

Manufacturer / TM Owner

Biofarm Sp. Z O.O.

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Indications & Clinical Uses

  • Ketoprofen lysine is an NSAID that alleviates pain and inflammation by targeting cyclo‑oxygenase pathways.
  • Mild to moderate acute pain: provides analgesic relief for short‑term pain episodes.
  • Osteoarthritis: reduces joint pain and improves mobility in degenerative joint disease.
  • Rheumatoid arthritis: helps control inflammatory joint pain and swelling.
  • Musculoskeletal injuries: eases pain and inflammation from sprains, strains, and back pain.
  • Dysmenorrhea: relieves menstrual cramps and associated discomfort.

How It Works

  • Ketoprofen lysine exerts its effect by non‑selectively inhibiting cyclo‑oxygenase‑1 (COX‑1) and cyclo‑oxygenase‑2 (COX‑2) enzymes, which blocks the conversion of arachidonic acid to prostaglandins. The resulting decrease in prostaglandin synthesis diminishes inflammation, lowers peripheral sensitization of nociceptors, and provides analgesic and antipyretic actions throughout the body.

Side Effects

Ketoprofen lysine may cause a range of adverse reactions, varying from mild to serious.

Common Side Effects

  • Gastrointestinal discomfort: nausea, dyspepsia, or abdominal pain.
  • Headache: mild to moderate head pain.
  • Dizziness: sensation of light‑headedness or vertigo.
  • Skin rash: mild erythema or itching.

Serious or Rare Side Effects

  • Gastrointestinal ulceration or bleeding: potentially life‑threatening hemorrhage.
  • Renal impairment: reduced kidney function or acute kidney injury.
  • Severe hypersensitivity: anaphylaxis, angioedema, or Stevens‑Johnson syndrome.

Precautions & Warnings

  • When prescribing or dispensing ketoprofen lysine, consider the following precautions to minimize risk.
  • Assess gastrointestinal risk: avoid in patients with active ulcers or history of GI bleeding.
  • Monitor renal function: use cautiously in patients with renal impairment or dehydration.
  • Cardiovascular caution: limit use in patients with established heart disease or hypertension.
  • Avoid concomitant NSAIDs or anticoagulants: increased bleeding risk.
  • Pregnancy and lactation: evaluate benefit‑risk; use only if clearly needed.
  • Store at ambient temperature: keep below 25 °C in original packaging, protect from moisture.

Avoid Interactions

Ketoprofen lysine can interact with several medicines, altering efficacy or safety.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased risk of bleeding.
  • Selective COX‑2 inhibitors: additive gastrointestinal toxicity.
  • High‑dose corticosteroids: heightened ulcer risk.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: may reduce renal perfusion, monitor kidney function.
  • Diuretics: potential for electrolyte imbalance, monitor labs.
  • Lithium: NSAIDs can raise lithium levels, monitor serum concentration.

Frequently Asked Questions

Ketoflix contains ketoprofen lysine, an NSAID indicated for the relief of mild to moderate pain and for reducing inflammation in conditions such as osteoarthritis, rheumatoid arthritis, musculoskeletal injuries, and dysmenorrhea. It is prescribed to adult patients who need symptomatic control of pain and swelling.

Ketoprofen lysine works by non‑selectively inhibiting the cyclo‑oxygenase enzymes COX‑1 and COX‑2, which blocks the formation of prostaglandins. Lower prostaglandin levels reduce inflammation, decrease peripheral sensitisation of pain receptors, and produce analgesic and antipyretic effects throughout the body.

The appropriate dose of Ketoflix is determined by the prescribing healthcare professional based on the patient’s condition, age, weight, and response to therapy. Dosage recommendations are provided in the product’s prescribing information and should be followed exactly as directed by the prescriber.

Safety data for ketoprofen lysine in pregnancy and lactation are limited. The drug should only be used during pregnancy or while breastfeeding if the potential benefit justifies the potential risk to the fetus or infant. Healthcare providers should evaluate each case individually.

To order Ketoflix, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams across international markets. After the request, the sales team will verify trade or institutional credentials, then provide pricing, availability, shipping details and any required import documentation.

Ketoflix (ketoprofen lysine) and other NSAIDs such as ibuprofen share a similar mechanism of COX inhibition, but ketoprofen is often considered slightly more potent on a milligram‑per‑milligram basis. Differences may include onset of action, duration of effect, and individual tolerability profiles, which should be assessed by the prescriber.

Ketoflix tablets should be stored at ambient temperature, preferably below 25 °C, in the original packaging to protect them from moisture and light. Keep the product out of reach of children and do not use it after the expiration date printed on the label.

Ketoflix is taken orally, usually with a full glass of water. It may be taken with or without food, although taking it with food can help reduce gastrointestinal discomfort. Patients should follow the dosing schedule prescribed by their healthcare professional.

Serious risks include gastrointestinal ulceration or bleeding, severe renal impairment, and hypersensitivity reactions such as anaphylaxis or Stevens‑Johnson syndrome. Patients should seek immediate medical attention if they experience symptoms like black stools, sudden kidney problems, severe rash, or difficulty breathing.

Ketoflix should be avoided in individuals with known hypersensitivity to ketoprofen or other NSAIDs, active gastrointestinal ulcers, severe heart failure, uncontrolled hypertension, or significant renal or hepatic impairment. It is also contraindicated in patients who have experienced a recent coronary artery bypass graft surgery.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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