Product image of Ketolek (Ketoprofen) supplied by GNH India

Ketolek

Active Ingredient:
Ketoprofen
Origin:
EU

Ketolek (Ketoprofen)

Ketoprofen, the active ingredient in Ketolek, is a nonsteroidal anti-inflammatory drug (NSAID) presented as an oral formulation for oral use. It treats mild to moderate pain and inflammatory conditions such as rheumatoid arthritis, osteoarthritis, musculoskeletal pain, and dysmenorrhea in adults.

GNH India supplies Ketolek as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Sun-Farm Sp. Z.O.O.

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Indications & Clinical Uses

Ketoprofen, an NSAID, reduces inflammation and pain by inhibiting cyclooxygenase enzymes in various disease states.

  • Mild to moderate pain: provides analgesic relief for acute or chronic pain conditions.
  • Rheumatoid arthritis: decreases joint inflammation and improves mobility.
  • Osteoarthritis: alleviates chronic joint discomfort and swelling.
  • Dysmenorrhea: reduces menstrual cramp intensity and associated pain.

How It Works

  • Ketoprofen exerts its effect through reversible inhibition of both cyclooxygenase‑1 (COX‑1) and cyclooxygenase‑2 (COX‑2) enzymes, leading to a decrease in prostaglandin synthesis. The reduced prostaglandin levels diminish inflammation, pain signaling, and fever generation at the site of tissue injury.

Side Effects

Ketolek may cause a range of adverse reactions, most of which are related to its NSAID class.

Common Side Effects

  • Gastrointestinal upset: nausea, dyspepsia, or abdominal discomfort.
  • Headache: mild to moderate intensity.
  • Dizziness or light‑headedness.
  • Skin rash: mild erythema or itching.
  • Elevated liver enzymes: transient laboratory changes.

Serious or Rare Side Effects

  • Gastrointestinal bleeding or ulceration.
  • Acute renal impairment or worsening of chronic kidney disease.
  • Severe hepatic injury or hepatitis.
  • Life‑threatening skin reactions such as Stevens‑Johnson syndrome.
  • Anaphylaxis: sudden, severe allergic reaction.

Precautions & Warnings

Before initiating therapy with Ketolek, consider the following safety measures.

  • Assess gastrointestinal risk: evaluate history of ulcers or bleeding before prescribing.
  • Monitor renal function: check baseline creatinine in patients with kidney disease.
  • Evaluate cardiovascular status: use caution in patients with hypertension or heart failure.
  • Review concomitant medications: avoid combining with other NSAIDs or anticoagulants when possible.
  • Store at ambient temperature: keep below 25°C in the original packaging, protect from moisture.

Avoid Interactions

Ketolek can interact with several drug classes, requiring careful management.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased risk of serious bleeding.
  • Other NSAIDs or aspirin: additive gastrointestinal toxicity.
  • Lithium: heightened lithium serum concentrations.

Moderate Interactions (Monitor Closely)

  • Methotrexate: reduced renal clearance may raise toxicity.
  • ACE inhibitors or ARBs: potential for reduced renal function, especially in volume‑depleted patients.

Frequently Asked Questions

Ketolek, containing ketoprofen, is indicated for mild to moderate pain, rheumatoid arthritis, osteoarthritis, musculoskeletal pain, and dysmenorrhea. It is prescribed to reduce inflammation and provide analgesic relief in these adult patient populations.

Ketoprofen works by reversibly inhibiting cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, which are essential for prostaglandin production. Lower prostaglandin levels lead to reduced inflammation, pain signaling, and fever, providing therapeutic benefit in inflammatory conditions.

The specific dose of Ketolek is determined by the prescribing healthcare professional based on the individual’s condition, severity, and response. Dosage recommendations follow the approved labeling for ketoprofen and should be individualized by the prescriber.

Ketoprofen, like other NSAIDs, is generally avoided during the third trimester of pregnancy due to potential fetal risks. Safety in early pregnancy and lactation has not been fully established, so clinicians should weigh benefits against possible risks and consider alternative therapies when appropriate.

To order Ketolek, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Ketolek (ketoprofen) and ibuprofen belong to the same NSAID class but differ in potency and pharmacokinetics. Ketoprofen often provides longer‑lasting analgesia and may be more effective for certain inflammatory conditions, while ibuprofen is widely used for mild pain with a shorter half‑life. Choice depends on clinical response, safety profile, and physician preference.

Ketolek should be stored at ambient temperature, preferably below 25 °C. Keep the product in its original packaging, protect it from moisture and direct sunlight, and ensure the container is tightly closed to maintain stability.

Ketolek is taken orally, usually with a full glass of water. It may be taken with or without food, but patients who experience stomach upset are advised to ingest it with meals to minimize gastrointestinal irritation.

Serious risks include gastrointestinal bleeding or ulceration, acute kidney injury, severe liver injury, life‑threatening skin reactions such as Stevens‑Johnson syndrome, and anaphylaxis. Patients should be monitored for signs of these events, especially if they have pre‑existing risk factors.

Ketolek is contraindicated in individuals with known hypersensitivity to ketoprofen or other NSAIDs, active gastrointestinal bleeding or ulcer disease, severe renal or hepatic impairment, and in the third trimester of pregnancy. Caution is also advised for patients on anticoagulants or other NSAIDs.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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