Product image of Ketonal Forte Sr (Ketoprofen) supplied by GNH India

Ketonal Forte Sr

Active Ingredient:
Ketoprofen
Origin:
EU

Ketonal Forte Sr (Ketoprofen)

Ketoprofen, the active ingredient in Ketonal Forte Sr, is a nonsteroidal anti-inflammatory drug (NSAID) presented as an oral tablet for systemic use. It is employed to relieve mild to moderate pain and to reduce inflammation in musculoskeletal disorders such as osteoarthritis and rheumatoid arthritis.

GNH India supplies Ketonal Forte Sr as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Sandoz Polska Sp. Z O.O.

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Indications & Clinical Uses

Ketoprofen acts as an NSAID that reduces inflammation and pain in several musculoskeletal conditions.

  • Mild to moderate pain: provides analgesic relief for acute or chronic pain episodes.
  • Osteoarthritis: diminishes joint pain and improves functional mobility.
  • Rheumatoid arthritis: helps control inflammatory joint swelling and stiffness.
  • Inflammatory musculoskeletal conditions: reduces swelling and discomfort in tendonitis, bursitis and similar disorders.

How It Works

  • Ketoprofen non‑selectively inhibits cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, decreasing the conversion of arachidonic acid to prostaglandins. The reduced prostaglandin synthesis leads to lower inflammation, pain signaling, and fever responses in affected tissues.

Side Effects

Ketoprofen may cause a range of adverse reactions, from mild to serious.

Common Side Effects

  • Gastrointestinal discomfort or dyspepsia
  • Headache
  • Dizziness
  • Skin rash or pruritus
  • Mild elevation of liver enzymes

Serious or Rare Side Effects

  • Gastrointestinal ulceration or bleeding
  • Acute renal impairment or failure
  • Severe skin reactions such as Stevens‑Johnson syndrome
  • Hepatotoxicity with marked enzyme elevation
  • Anaphylactic or anaphylactoid reactions

Precautions & Warnings

Before initiating therapy, consider the following safety measures.

  • Assess renal function: adjust or avoid use in patients with significant renal impairment.
  • Monitor gastrointestinal risk: avoid in individuals with a history of ulcer or bleeding.
  • Avoid concomitant anticoagulants: increased risk of hemorrhage.
  • Use caution in cardiovascular disease: NSAIDs may elevate cardiovascular event risk.
  • Pregnancy and lactation: consult a healthcare professional before use.
  • Store at ambient temperature: keep in the original pack, protect from moisture.

Avoid Interactions

Ketoprofen can interact with several drug classes, requiring careful management.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): heightened bleeding risk.
  • Other NSAIDs or COX‑2 inhibitors: additive gastrointestinal toxicity.
  • Selective serotonin reuptake inhibitors (SSRIs): increased bleeding potential.
  • ACE inhibitors or diuretics: may impair renal function.
  • Lithium: can raise serum lithium concentrations.

Moderate Interactions (Monitor Closely)

  • Corticosteroids: synergistic ulcer risk.
  • Methotrexate: reduced clearance, possible toxicity.
  • Cyclosporine: enhanced nephrotoxic effect.
  • Diabetes medications: possible alteration of glycemic control.
  • Diuretics: potential electrolyte disturbances.

Frequently Asked Questions

Ketonal Forte Sr contains ketoprofen, an NSAID that is commonly prescribed to manage mild to moderate pain, osteoarthritis, rheumatoid arthritis, and other inflammatory musculoskeletal conditions. It works by reducing inflammation and providing analgesic relief in these disorders.

Ketoprofen inhibits both cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, which blocks the formation of prostaglandins—key mediators of inflammation, pain, and fever. By lowering prostaglandin levels, ketoprofen reduces tissue inflammation and diminishes pain signals.

The specific dose of Ketonal Forte Sr is determined by the prescribing healthcare professional based on the patient’s condition, severity of symptoms, age, renal and hepatic function, and other individual factors. Patients should follow the prescriber’s instructions and not adjust the dose on their own.

Ketoprofen, like other NSAIDs, should be used only if clearly needed during pregnancy, especially in the third trimester, because of potential risks to the fetus. Breastfeeding mothers should consult their physician, as ketoprofen can be excreted in breast milk and may affect the infant.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Ketoprofen and ibuprofen belong to the same NSAID class but differ in potency and pharmacokinetics. Ketoprofen generally offers stronger anti‑inflammatory effects at lower doses, while ibuprofen is often used for milder pain. Both share similar safety profiles, though individual tolerance and specific clinical scenarios guide the choice.

Ketonal Forte Sr should be stored at ambient temperature, below 25 °C. Keep the tablets in their original packaging, protect them from moisture and direct sunlight, and ensure they are out of reach of children.

Ketonal Forte Sr is taken orally, usually with a full glass of water. It can be taken with or without food, but taking it with food may reduce gastrointestinal discomfort. The exact timing and frequency are set by the prescribing clinician.

Serious risks include gastrointestinal ulceration or bleeding, acute kidney injury, severe skin reactions such as Stevens‑Johnson syndrome, hepatotoxicity, and increased cardiovascular events. Patients should be monitored for signs of these conditions and seek immediate medical attention if they occur.

Ketonal Forte Sr should be avoided in individuals with known hypersensitivity to ketoprofen or other NSAIDs, active gastrointestinal ulcer or bleeding, severe renal or hepatic impairment, uncontrolled heart failure, and in the third trimester of pregnancy unless absolutely necessary.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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