Product image of Ketonal Rapid (Ketoprofen) supplied by GNH India

Ketonal Rapid

Active Ingredient:
Ketoprofen
Origin:
EU

Ketonal Rapid (Ketoprofen)

Ketoprofen, the active ingredient in Ketonal Rapid, is a nonsteroidal anti-inflammatory drug (NSAID) presented as an oral tablet for oral use. It treats pain and inflammation in conditions such as rheumatoid arthritis, osteoarthritis and musculoskeletal disorders.

GNH India supplies Ketonal Rapid as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Sandoz D.O.O.

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Indications & Clinical Uses

Ketoprofen is indicated for inflammatory and painful conditions affecting the musculoskeletal system.

  • Rheumatoid arthritis: reduces joint pain, swelling and stiffness.
  • Osteoarthritis: alleviates chronic joint discomfort and improves mobility.
  • Musculoskeletal pain: provides relief from acute injuries, strains and sprains.
  • Acute pain: manages short‑term pain such as postoperative or dental pain.

How It Works

  • Ketoprofen exerts its effect by non‑selectively inhibiting cyclooxygenase enzymes COX‑1 and COX‑2, which decreases the conversion of arachidonic acid to prostaglandins. The resulting reduction in prostaglandin synthesis diminishes inflammation, pain signaling, and fever responses at the site of tissue injury.

Side Effects

Ketoprofen may cause a range of adverse reactions, varying from mild to severe.

Common Side Effects

  • Gastrointestinal discomfort: nausea, dyspepsia or abdominal pain.
  • Headache: mild to moderate intensity.
  • Dizziness or vertigo.
  • Skin rash: mild erythema or itching.

Serious or Rare Side Effects

  • Gastrointestinal ulceration or bleeding.
  • Severe allergic reactions: anaphylaxis, angioedema.
  • Renal impairment: sudden decrease in kidney function.

Precautions & Warnings

Ketoprofen should be used with caution in several clinical situations.

  • Assess gastrointestinal risk: evaluate history of ulcers or bleeding before use.
  • Monitor renal function: avoid in patients with severe kidney disease.
  • Use caution in cardiovascular disease: NSAIDs may increase risk of thrombotic events.
  • Avoid in late pregnancy: NSAIDs are contraindicated in the third trimester.
  • Review concomitant medications: consider interactions with anticoagulants or antihypertensives.
  • Store at ambient temperature: keep below 25°C, retain in original packaging and protect from moisture.

Avoid Interactions

Ketoprofen can interact with several drug classes, requiring attention to avoid harmful effects.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased risk of bleeding.
  • Other NSAIDs or COX‑2 inhibitors: additive gastrointestinal toxicity.
  • Corticosteroids: heightened ulcer risk.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: may reduce renal perfusion, monitor kidney function.
  • Diuretics: potential for reduced efficacy of antihypertensive effect.
  • Lithium: NSAIDs can raise lithium serum levels, monitor concentrations.

Frequently Asked Questions

Ketonal Rapid contains ketoprofen, an NSAID that is used to relieve pain and reduce inflammation associated with conditions such as rheumatoid arthritis, osteoarthritis, acute musculoskeletal injuries, and other short‑term painful states.

Ketoprofen works by non‑selectively inhibiting the cyclooxygenase enzymes COX‑1 and COX‑2. This inhibition lowers prostaglandin production, which in turn diminishes inflammation, pain signaling, and fever at the site of tissue injury.

The appropriate dose of Ketonal Rapid is determined by the prescribing healthcare professional based on the patient’s condition, age, weight, and overall health status. Patients should follow the prescriber’s instructions and not adjust the dose on their own.

Ketoprofen, like other NSAIDs, is generally avoided in the third trimester of pregnancy because it may affect fetal cardiovascular function. Use during early pregnancy or while breastfeeding should be discussed with a healthcare provider, who can weigh potential benefits against risks.

To order Ketonal Rapid, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Both ketoprofen and ibuprofen belong to the NSAID class and share similar mechanisms of COX inhibition. Ketoprofen often has a slightly longer half‑life, which may allow for less frequent dosing, but individual response and safety profiles vary, so the choice depends on clinical judgment and patient tolerance.

Ketonal Rapid should be stored at ambient temperature, preferably below 25 °C. Keep the tablets in the original packaging, protect them from moisture and direct sunlight, and keep them out of reach of children.

Ketonal Rapid is taken orally, usually with a full glass of water. It can be taken with or without food, but patients who experience stomach upset may benefit from taking it with meals or an antacid, as advised by their prescriber.

Serious risks include gastrointestinal bleeding or ulceration, severe allergic reactions such as anaphylaxis, and acute kidney injury. Patients should seek immediate medical attention if they notice black stools, severe abdominal pain, swelling of the face or throat, or sudden loss of urine output.

Ketonal Rapid should be avoided by individuals with known hypersensitivity to ketoprofen or other NSAIDs, patients with active gastrointestinal ulceration, severe renal or hepatic impairment, and those in the third trimester of pregnancy. A healthcare professional should evaluate any other contraindications before prescribing.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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