Product image of Momenactcompi’ (Ketoprofen) supplied by GNH India

Momenactcompi’

Active Ingredient:
Ketoprofen
Origin:
EU

Momenactcompi’ (Ketoprofen)

Ketoprofen, the active ingredient in Momenactcompi’, is a nonsteroidal anti‑inflammatory drug (NSAID) presented as an oral formulation for systemic use. It is employed to relieve mild to moderate pain and to reduce inflammation in conditions such as rheumatoid arthritis, osteoarthritis and other musculoskeletal disorders, and is frequently prescribed for postoperative discomfort and acute injuries. The drug is absorbed rapidly after oral intake, reaching peak plasma concentrations within one to two hours, and its anti‑inflammatory effect can last up to 12 hours.
GNH India supplies Momenactcompi’ as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies, clinics and research institutions worldwide.

Manufacturer / TM Owner

Angelini Pharma S.P.A.

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Indications & Clinical Uses

Ketoprofen is indicated for inflammatory and painful conditions affecting the musculoskeletal system.

  • Rheumatoid arthritis: reduces joint swelling, pain and stiffness.
  • Osteoarthritis: alleviates pain and improves joint function.
  • Musculoskeletal pain: provides relief from strains, sprains and back pain.
  • Mild to moderate acute pain: controls postoperative or injury‑related discomfort.

How It Works

  • Ketoprofen exerts its effect by reversibly inhibiting cyclooxygenase‑1 (COX‑1) and cyclooxygenase‑2 (COX‑2) enzymes, which blocks the conversion of arachidonic acid to prostaglandins. The reduction in prostaglandin synthesis diminishes inflammation, pain signaling and fever, while preserving platelet function to a lesser extent compared with selective COX‑2 inhibitors. This non‑selective inhibition leads to a broad anti‑inflammatory profile, making ketoprofen effective in both acute and chronic inflammatory states.

Side Effects

Ketoprofen may cause a range of adverse reactions, varying from mild to serious.

Common Side Effects

  • Gastrointestinal discomfort: nausea, dyspepsia or abdominal pain.
  • Headache: mild to moderate intensity.
  • Dizziness or vertigo.
  • Skin rash or itching.

Serious or Rare Side Effects

  • Peptic ulcer disease or gastrointestinal bleeding.
  • Severe hypersensitivity reactions: Stevens‑Johnson syndrome or toxic epidermal necrolysis.
  • Renal impairment: acute kidney injury or worsening of chronic kidney disease.

Precautions & Warnings

When prescribing ketoprofen, several precautionary measures should be observed to minimize risk.

  • Assess gastrointestinal risk: evaluate history of ulcers or NSAID‑related bleeding.
  • Monitor renal function: especially in patients with dehydration, heart failure or pre‑existing kidney disease.
  • Check cardiovascular status: use cautiously in individuals with hypertension or established cardiovascular disease.
  • Review concomitant medications: avoid use with other NSAIDs, anticoagulants or corticosteroids without supervision.
  • Pregnancy and lactation: contraindicated or use only if benefits outweigh risks; consult obstetric guidance.
  • Store at ambient temperature: keep below 25 °C in the original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Ketoprofen can interact with several medicines, altering its efficacy or safety profile.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased bleeding risk.
  • Selective COX‑2 inhibitors: additive gastrointestinal toxicity.
  • High‑dose aspirin: enhanced renal adverse effects.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: may reduce renal function when combined.
  • Diuretics: potential for electrolyte imbalance and renal impairment.
  • Lithium: NSAIDs can increase lithium serum levels.
  • Methotrexate: reduced clearance leading to toxicity.

Frequently Asked Questions

Momenactcompi’ contains ketoprofen, an NSAID that is used to relieve mild to moderate pain and to reduce inflammation in conditions such as rheumatoid arthritis, osteoarthritis, musculoskeletal injuries and other acute painful states.

Ketoprofen works by reversibly inhibiting the cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, which blocks the formation of prostaglandins. Lower prostaglandin levels decrease inflammation, pain signalling and fever, providing an overall anti‑inflammatory effect.

The appropriate dose of ketoprofen is determined by the prescribing healthcare professional based on the individual’s condition, age, weight and response to therapy. Patients should follow the prescriber’s instructions and not adjust the dose on their own.

Ketoprofen is generally avoided during pregnancy, especially in the third trimester, because of potential risks to the fetus. Use while breastfeeding is also discouraged unless the benefits outweigh the risks, and only under medical supervision.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Both ketoprofen and ibuprofen are non‑selective NSAIDs, but ketoprofen often provides longer‑lasting pain relief and may be more potent on a milligram‑per‑milligram basis. However, the safety profile is similar, and the choice depends on clinical response, tolerability and physician preference.

Store the product at ambient temperature, preferably below 25 °C, in its original container. Keep it away from moisture, direct sunlight and heat sources. Do not use if the packaging is damaged or the tablets appear discoloured.

Momenactcompi’ is taken orally, usually with a full glass of water. It may be taken with or without food, although taking it with food can reduce gastrointestinal discomfort. Follow the prescriber’s dosing schedule precisely.

Serious risks include gastrointestinal bleeding or ulceration, severe hypersensitivity reactions such as Stevens‑Johnson syndrome, renal impairment that can progress to acute kidney injury, and increased cardiovascular events like myocardial infarction or stroke.

Ketoprofen should be avoided by individuals with a known hypersensitivity to ketoprofen or other NSAIDs, those with active peptic ulcer disease, severe heart failure, uncontrolled hypertension, significant renal or hepatic impairment, and by pregnant women in the third trimester unless absolutely necessary.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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