Product image of Ketoprofen Lgo (Ketoprofen) supplied by GNH India

Ketoprofen Lgo

Active Ingredient:
Ketoprofen
Origin:
EU

Ketoprofen Lgo (Ketoprofen)

Ketoprofen, the active ingredient in Ketoprofen Lgo, is a nonsteroidal anti-inflammatory drug (NSAID) presented as a topical formulation for cutaneous use. It is employed to alleviate pain and reduce inflammation in musculoskeletal and arthritic conditions. It is commonly applied to affected areas twice daily, providing localized relief while minimizing systemic exposure.

GNH India supplies Ketoprofen Lgo as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides reliable logistics for global distribution. Clients benefit from consistent product availability, regulatory support, and dedicated technical assistance throughout.

Manufacturer / TM Owner

Laboratorium Galenowe Olsztyn Sp. Z O.O.

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Indications & Clinical Uses

Ketoprofen is an NSAID that reduces inflammation and pain in musculoskeletal and arthritic disorders.

  • Musculoskeletal pain: provides topical analgesia and reduces inflammation at the application site.
  • Osteoarthritis: alleviates joint pain and improves mobility in affected joints.
  • Rheumatoid arthritis: diminishes localized inflammation and discomfort in peripheral joints.
  • Soft tissue injuries: eases pain and swelling from sprains or strains.
  • Post‑operative inflammation: helps control localized swelling after minor surgical procedures.

How It Works

  • Ketoprofen exerts its effect by reversibly inhibiting cyclooxygenase‑1 (COX‑1) and cyclooxygenase‑2 (COX‑2) enzymes in peripheral tissues. This inhibition blocks the conversion of arachidonic acid to prostaglandins, which are key mediators of inflammation, pain and fever. The resulting decrease in prostaglandin synthesis reduces vascular permeability, edema and nociceptor activation at the site of application.

Side Effects

Topical ketoprofen may cause a range of skin‑related adverse reactions, from mild irritation to rare systemic events.

Common Side Effects

  • Skin irritation: mild burning or stinging at the application site.
  • Redness: localized erythema.
  • Itching: pruritus around the treated area.
  • Dryness: skin dryness or flaking.

Serious or Rare Side Effects

  • Allergic reaction: angioedema or anaphylaxis.
  • Severe dermatitis: extensive blistering or contact dermatitis.
  • Photosensitivity: exaggerated sunburn response.
  • Systemic NSAID effects: gastrointestinal ulceration or bleeding.

Precautions & Warnings

When using topical ketoprofen, several safety considerations should be observed to minimize risks.

  • Avoid use on broken skin: apply only to intact, healthy skin.
  • Limit sun exposure: risk of photosensitivity, use sunscreen or protective clothing.
  • Do not combine with other NSAIDs: increased risk of systemic adverse effects.
  • Use with caution in elderly: higher susceptibility to systemic absorption and renal effects.
  • Pregnancy and breastfeeding: consult a healthcare professional before use.
  • Store below 25°C: keep in the original pack, protect from moisture and light.

Avoid Interactions

Ketoprofen can interact with other medicines, altering efficacy or safety.

Major Interactions (Avoid)

  • Concurrent oral NSAIDs: increased risk of gastrointestinal bleeding.
  • Anticoagulants (warfarin, DOACs): heightened bleeding tendency.
  • Corticosteroids: additive risk of gastrointestinal ulceration.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors: possible reduction in renal function.
  • Diuretics: risk of renal impairment with combined use.
  • Lithium: ketoprofen may raise lithium serum levels.

Frequently Asked Questions

Ketoprofen Lgo is a topical formulation of the NSAID ketoprofen. It is applied to the skin to relieve pain and reduce inflammation associated with musculoskeletal disorders, osteoarthritis, rheumatoid arthritis, soft‑tissue injuries and localized post‑operative swelling.

Ketoprofen works by reversibly blocking the cyclooxygenase‑1 and cyclooxygenase‑2 enzymes. This inhibition prevents the formation of prostaglandins, which are chemicals that promote inflammation, pain and fever. Lower prostaglandin levels lead to reduced swelling and analgesic effects at the site of application.

The specific dose and frequency are determined by the prescribing healthcare professional based on the condition being treated, the size of the affected area and patient factors. Typically, a thin layer is applied to the skin and may be repeated two to three times daily, but exact instructions must come from the prescriber.

Safety in pregnancy and lactation has not been definitively established for topical ketoprofen. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss potential risks with their healthcare provider before using the product.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and necessary import documentation.

Ketoprofen Lgo is comparable to other topical NSAIDs such as diclofenac gel. Both provide localized pain relief with limited systemic exposure. Ketoprofen may have a slightly stronger COX‑1/COX‑2 inhibition profile, which can translate into effective anti‑inflammatory action, but individual response and tolerability can vary, so selection should be based on clinical judgment.

Store Ketoprofen Lgo below 25 °C in its original packaging. Protect the container from moisture, direct sunlight and extreme temperatures. Keep the product out of reach of children and avoid using it after the expiry date indicated on the label.

Ketoprofen Lgo is applied externally to clean, dry, intact skin. A thin layer is spread over the affected area and gently massaged until absorbed. The exact amount and frequency should follow the prescribing clinician’s directions, and hands should be washed after application to prevent accidental contact with eyes or mucous membranes.

Serious risks, although rare, include severe allergic reactions such as angioedema or anaphylaxis, extensive contact dermatitis, photosensitivity leading to severe sunburn, and systemic NSAID effects like gastrointestinal ulceration or bleeding if significant systemic absorption occurs.

Ketoprofen Lgo should be avoided in individuals with known hypersensitivity to ketoprofen or any NSAID, those with broken or infected skin at the intended site, patients with a history of severe photosensitivity, and anyone currently using other topical or systemic NSAIDs without medical advice.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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