Product image of Ketoprofen Dompé (Ketoprofen Lysine) supplied by GNH India

Ketoprofen Dompé

Active Ingredient:
Ketoprofen Lysine
Origin:
EU

Ketoprofen Dompé (Ketoprofen Lysine)

Ketoprofen lysine, the active ingredient in Ketoprofen Dompé, is a nonsteroidal anti-inflammatory drug presented as an oral formulation for oral use. It is employed to relieve mild to moderate pain, reduce inflammation in arthritic conditions, and manage menstrual cramps in adults.

GNH India supplies Ketoprofen Dompé as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Dompé Farmaceutici S.P.A.

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Ketoprofen Dompé acts on inflammatory pathways to provide analgesic and anti‑inflammatory effects in several musculoskeletal and gynecologic conditions.

  • Mild to moderate pain: provides rapid analgesic relief for acute or chronic discomfort.
  • Rheumatoid arthritis: reduces joint inflammation and pain, improving mobility.
  • Osteoarthritis: alleviates chronic joint stiffness and soreness.
  • Musculoskeletal pain: eases strain‑related aches in muscles and tendons.
  • Dysmenorrhea: lessens menstrual cramps and associated pelvic pain.

How It Works

  • Ketoprofen lysine exerts its effect by non‑selectively inhibiting cyclooxygenase‑1 (COX‑1) and cyclooxygenase‑2 (COX‑2) enzymes. This inhibition blocks the conversion of arachidonic acid to prostaglandins, thereby decreasing prostaglandin-mediated inflammation, pain signalling, and fever generation throughout the body.

Side Effects

Ketoprofen Dompé may cause a range of adverse reactions, from mild to severe, depending on individual susceptibility and duration of therapy.

Common Side Effects

  • Gastrointestinal discomfort: nausea, dyspepsia, or abdominal pain.
  • Headache: mild to moderate intensity.
  • Dizziness or vertigo.
  • Skin rash or mild itching.
  • Elevated blood pressure.

Serious or Rare Side Effects

  • Gastrointestinal bleeding or ulcer perforation.
  • Severe renal impairment or acute kidney injury.
  • Hepatic dysfunction with elevated liver enzymes.
  • Anaphylactic or severe allergic reactions.
  • Stevens‑Johnson syndrome or toxic epidermal necrolysis.
  • Cardiovascular events such as myocardial infarction or stroke.

Precautions & Warnings

Before initiating therapy with Ketoprofen Dompé, clinicians should evaluate patient‑specific risk factors and monitor for potential complications.

  • Assess gastrointestinal risk: review history of ulcers or bleeding before prescribing.
  • Monitor renal function: check serum creatinine in patients with existing kidney disease.
  • Evaluate cardiovascular status: use caution in patients with hypertension or heart disease.
  • Avoid in known hypersensitivity: discontinue immediately if allergic signs appear.
  • Use the lowest effective dose for the shortest duration needed to control symptoms.
  • Store at ambient temperature: keep in the original container, protect from moisture and light.

Avoid Interactions

Ketoprofen Dompé can interact with several drug classes, altering efficacy or increasing toxicity.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): heightened risk of serious bleeding.
  • Concurrent NSAIDs: additive gastrointestinal toxicity.
  • Selective serotonin reuptake inhibitors (SSRIs): increased bleeding tendency.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: possible decline in renal function.
  • Diuretics: risk of reduced renal perfusion and electrolyte imbalance.
  • Lithium: ketoprofen may raise serum lithium concentrations, requiring monitoring.

Frequently Asked Questions

Ketoprofen Dompé is indicated for the relief of mild to moderate pain, including musculoskeletal discomfort, and for reducing inflammation in rheumatoid arthritis, osteoarthritis, and other inflammatory joint conditions. It is also used to manage dysmenorrhea, providing relief from menstrual cramps.

Ketoprofen lysine works by non‑selectively inhibiting the cyclooxygenase enzymes COX‑1 and COX‑2. This blocks the synthesis of prostaglandins, which are key mediators of inflammation, pain, and fever. By reducing prostaglandin levels, the drug diminishes the inflammatory response and the perception of pain.

The appropriate dose of Ketoprofen Dompé is determined by the prescribing healthcare professional based on the patient’s age, weight, severity of symptoms, and overall medical condition. Dosage regimens may vary, and patients should follow the specific instructions provided by their prescriber.

Safety data for ketoprofen lysine in pregnancy and lactation are limited. It should only be used if the potential benefit justifies the potential risk to the fetus or infant. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss use with their healthcare provider.

To order Ketoprofen Dompé, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, confirming trade or institutional credentials before providing pricing, availability, shipping details, and any necessary import documentation.

Ketoprofen and ibuprofen belong to the same NSAID class and share a similar mechanism of COX inhibition. Ketoprofen is often considered more potent on a milligram‑per‑milligram basis, which may allow lower dosing for comparable analgesic effect. However, both carry similar gastrointestinal, renal, and cardiovascular risks, so choice depends on clinical response and tolerability.

Ketoprofen Dompé should be stored at ambient temperature, below 25 °C (77 °F). Keep the product in its original packaging, protect it from moisture, excessive heat, and direct sunlight to maintain stability and potency throughout its shelf life.

Ketoprofen Dompé is administered orally. The tablet should be swallowed whole with a full glass of water, preferably with food or milk to reduce gastrointestinal irritation. Patients should not crush, chew, or split the tablet unless specifically instructed by a healthcare professional.

The most serious risks include gastrointestinal bleeding or ulcer perforation, severe renal impairment, cardiovascular events such as heart attack or stroke, and rare but life‑threatening skin reactions like Stevens‑Johnson syndrome. Patients should be monitored for signs of these complications, especially during prolonged therapy.

Ketoprofen Dompé should be avoided in individuals with known hypersensitivity to ketoprofen or other NSAIDs, active peptic ulcer disease, severe heart failure, uncontrolled hypertension, significant renal or hepatic impairment, and in patients who have experienced serious cardiovascular events while using NSAIDs.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.