Product image of Ketoprofene Sale Di Lisina Dompé (Ketoprofen Lysine) supplied by GNH India

Ketoprofene Sale Di Lisina Dompé

Active Ingredient:
Ketoprofen Lysine
Origin:
EU

Ketoprofene Sale Di Lisina Dompé (Ketoprofen Lysine)

Ketoprofen lysine, the active ingredient in Ketoprofene Sale Di Lisina Dompé, is a nonsteroidal anti‑inflammatory drug (NSAID) presented as an oral tablet for systemic use. It is indicated for the relief of mild to moderate pain and for inflammatory conditions such as osteoarthritis, rheumatoid arthritis and other musculoskeletal disorders in adult patients.

GNH India supplies Ketoprofene Sale Di Lisina Dompé as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Dompé Farmaceutici S.P.A.

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Indications & Clinical Uses

Ketoprofen lysine is an NSAID that reduces inflammation and pain in several musculoskeletal and joint disorders.

  • Osteoarthritis: alleviates joint pain and improves mobility.
  • Rheumatoid arthritis: decreases inflammatory swelling and pain in affected joints.
  • Musculoskeletal pain: provides relief from strains, sprains and other soft‑tissue injuries.

How It Works

  • Ketoprofen lysine exerts its effect by non‑selectively inhibiting cyclooxygenase‑1 (COX‑1) and cyclooxygenase‑2 (COX‑2) enzymes. This inhibition reduces the conversion of arachidonic acid to prostaglandins, leading to decreased synthesis of inflammatory mediators, which in turn diminishes pain, fever, and inflammation at the site of tissue injury.

Side Effects

Ketoprofen lysine may cause a range of adverse reactions, most of which are related to its NSAID class.

Common Side Effects

  • Gastrointestinal discomfort: nausea, dyspepsia or abdominal pain.
  • Headache: mild to moderate intensity.
  • Dizziness or vertigo.
  • Skin reactions: rash or pruritus.
  • Elevated liver enzymes.

Serious or Rare Side Effects

  • Gastrointestinal ulceration or bleeding.
  • Severe renal impairment or acute kidney injury.
  • Cardiovascular events such as myocardial infarction or stroke.
  • Severe hypersensitivity reactions including anaphylaxis.
  • Hepatotoxicity with jaundice.

Precautions & Warnings

Before using ketoprofen lysine, consider the following safety measures.

  • Renal function: assess kidney health, especially in patients with pre‑existing renal disease.
  • Gastrointestinal risk: evaluate history of ulcers or bleeding; consider gastro‑protective therapy if needed.
  • Cardiovascular status: use cautiously in patients with heart disease or hypertension.
  • Concomitant drugs: review use of other NSAIDs, anticoagulants or corticosteroids for additive risk.
  • Pregnancy and lactation: avoid unless clearly indicated by a healthcare professional.
  • Store at ambient temperature: keep below 25 °C, retain in original packaging, and protect from moisture and direct sunlight.

Avoid Interactions

Ketoprofen lysine can interact with several medicines, altering efficacy or safety.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased risk of serious bleeding.
  • Other NSAIDs or COX‑2 inhibitors: heightened gastrointestinal toxicity.
  • Selective serotonin reuptake inhibitors (SSRIs): amplified bleeding tendency.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or diuretics: possible reduction in renal function.
  • Lithium: NSAIDs may raise lithium serum levels.
  • Methotrexate: decreased clearance leading to toxicity.

Frequently Asked Questions

Ketoprofene Sale Di Lisina Dompé contains ketoprofen lysine, an NSAID indicated for mild to moderate pain and for inflammatory disorders such as osteoarthritis, rheumatoid arthritis and other musculoskeletal conditions. It helps reduce pain, swelling and stiffness associated with these diseases.

Ketoprofen lysine works by blocking the activity of cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, which are essential for the production of prostaglandins. By lowering prostaglandin levels, the drug reduces inflammation, fever and the sensation of pain at the affected site.

The specific dose of Ketoprofene Sale Di Lisina Dompé is determined by the prescribing healthcare professional based on the patient’s condition, age, weight and overall health. Patients should follow the prescriber’s instructions and not adjust the dose on their own.

Safety of ketoprofen lysine in pregnancy or while breastfeeding has not been definitively established. It should only be used if the potential benefit justifies the potential risk to the fetus or infant, and this decision must be made by a qualified healthcare provider.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Ketoprofen lysine is similar to other NSAIDs in its mechanism of COX inhibition, but it is often noted for its relatively rapid onset of analgesia and strong anti‑inflammatory effect. Compared with ibuprofen or naproxen, ketoprofen may provide slightly longer pain relief, though individual response varies.

The product should be stored at ambient temperature, preferably below 25 °C. Keep the tablets in the original container, protect them from moisture, heat and direct sunlight, and ensure the packaging is tightly closed to maintain stability.

Ketoprofene Sale Di Lisina Dompé is taken orally, usually with a full glass of water. It can be taken with or without food, but taking it with food may reduce gastrointestinal discomfort for some patients.

Serious risks include gastrointestinal bleeding or ulceration, severe kidney injury, cardiovascular events such as heart attack or stroke, and rare but life‑threatening allergic reactions like anaphylaxis. Patients should seek immediate medical attention if they experience symptoms such as severe abdominal pain, blood in stools, sudden swelling, or difficulty breathing.

Individuals with a known hypersensitivity to ketoprofen, other NSAIDs, or any component of the formulation should avoid the product. It is also contraindicated in patients with active gastrointestinal bleeding, severe heart failure, or those who have had a recent coronary artery bypass graft surgery.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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