Product image of Ketoprofene Lp Viatris (Ketoprofen) supplied by GNH India

Ketoprofene Lp Viatris

Active Ingredient:
Ketoprofen
Origin:
EU

Ketoprofene Lp Viatris (Ketoprofen)

Ketoprofen, the active ingredient in Ketoprofene Lp Viatris, is a nonsteroidal anti-inflammatory drug (NSAID) presented as an oral dosage form for oral use. It treats mild to moderate pain, inflammatory musculoskeletal conditions, rheumatoid arthritis, osteoarthritis and dental pain in adults.
GNH India supplies Ketoprofene Lp Viatris as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Viatris Sante

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Indications & Clinical Uses

Ketoprofen is employed to relieve pain and inflammation in several related disease groups.

  • Mild to moderate pain: provides analgesia for acute or chronic pain conditions.
  • Rheumatoid arthritis: reduces joint inflammation and improves mobility.
  • Osteoarthritis: alleviates joint pain and stiffness associated with degenerative changes.
  • Dental pain: controls postoperative or inflammatory dental discomfort.
  • Inflammatory musculoskeletal conditions: diminishes swelling and tenderness in soft‑tissue injuries.

How It Works

  • Ketoprofen non‑selectively inhibits cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, decreasing the conversion of arachidonic acid to prostaglandins. The reduced prostaglandin synthesis leads to diminished inflammation, pain signaling, and fever response at sites of tissue injury.

Side Effects

Ketoprofen may cause a range of adverse reactions, which are grouped by frequency.

Common Side Effects

  • Gastrointestinal discomfort: nausea, dyspepsia, or abdominal pain.
  • Headache: mild to moderate intensity.
  • Dizziness or vertigo.
  • Skin rash or mild pruritus.
  • Elevated liver enzymes: asymptomatic laboratory finding.

Serious or Rare Side Effects

  • Gastrointestinal ulceration or bleeding.
  • Severe hepatic injury or jaundice.
  • Renal impairment or acute kidney injury.
  • Anaphylactic or severe hypersensitivity reactions.
  • Cardiovascular events such as myocardial infarction or stroke.

Precautions & Warnings

When prescribing or dispensing ketoprofen, consider the following precautions to minimize risk.

  • Assess renal function: avoid use in patients with severe renal impairment.
  • Monitor gastrointestinal risk: use gastro‑protective agents in high‑risk individuals.
  • Avoid in known hypersensitivity: discontinue if allergic reactions occur.
  • Use lowest effective dose: limit duration to the shortest period necessary.
  • Store at ambient temperature: keep in the original pack, protect from moisture.

Avoid Interactions

Ketoprofen can interact with other medicines, affecting efficacy or safety.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased bleeding risk.
  • Other NSAIDs or COX‑2 inhibitors: heightened gastrointestinal toxicity.
  • High‑dose aspirin: additive renal and gastric adverse effects.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: possible reduction in renal function.
  • Diuretics: may enhance nephrotoxic potential.
  • Lithium: NSAIDs can raise lithium serum levels.

Frequently Asked Questions

Ketoprofene Lp Viatris contains ketoprofen, an NSAID indicated for relief of mild to moderate pain, reduction of inflammation in rheumatoid arthritis and osteoarthritis, and control of dental or other inflammatory musculoskeletal pain.

Ketoprofen blocks both COX‑1 and COX‑2 enzymes, which reduces the production of prostaglandins that mediate inflammation, pain, and fever. By lowering prostaglandin levels, the drug diminishes swelling and discomfort at the site of injury.

The appropriate dose of ketoprofen is determined by the prescribing healthcare professional based on the patient’s condition, age, renal and hepatic function, and other individual factors. Patients should follow the prescriber’s instructions and not adjust the dose on their own.

Safety data for ketoprofen during pregnancy and lactation are limited. It is generally avoided, especially in the third trimester, because of potential fetal cardiovascular effects and possible excretion in breast milk. Consultation with a healthcare provider is essential before use.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Ketoprofen and ibuprofen share a similar mechanism of COX inhibition, but ketoprofen often provides longer‑lasting analgesia and may be more potent on a milligram‑per‑milligram basis. Both carry comparable gastrointestinal and cardiovascular risks, so choice depends on clinical response, dosing convenience and individual patient tolerance.

Ketoprofen should be stored at ambient temperature, below 25 °C, in its original packaging to protect it from moisture and light. Keep the product out of reach of children and do not use it after the expiry date indicated on the label.

Ketoprofen is administered orally, typically as tablets or capsules, and should be taken with a full glass of water. It may be taken with food or milk to reduce gastrointestinal irritation, unless the prescriber advises otherwise.

Serious risks include gastrointestinal ulceration or bleeding, severe liver injury, acute kidney failure, and rare but life‑threatening hypersensitivity reactions such as anaphylaxis. Patients should be monitored for signs of these events, especially if they have pre‑existing risk factors.

Ketoprofen is contraindicated in individuals with known hypersensitivity to ketoprofen or other NSAIDs, those with active gastrointestinal ulceration, severe renal or hepatic impairment, and patients in the third trimester of pregnancy. It should also be used with caution in patients with cardiovascular disease.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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