Product image of Ketoprofene Sale Di Lisina Eg (Ketoprofen Lysine) supplied by GNH India

Ketoprofene Sale Di Lisina Eg

Active Ingredient:
Ketoprofen Lysine
Origin:
EU

Ketoprofene Sale Di Lisina Eg (Ketoprofen Lysine)

Ketoprofen, the active ingredient in Ketoprofene Sale Di Lisina Eg, is a nonsteroidal anti-inflammatory drug presented as an oral tablet for oral use. It treats pain and inflammation in conditions such as rheumatoid arthritis, osteoarthritis, and musculoskeletal pain.

GNH India supplies Ketoprofene Sale Di Lisina Eg as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Eg S.P.A.

1
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Indications & Clinical Uses

Ketoprofen acts on inflammatory pathways to relieve pain and swelling in several musculoskeletal disorders.

  • Rheumatoid arthritis: reduces joint inflammation and pain, improving mobility.
  • Osteoarthritis: alleviates chronic joint discomfort and stiffness.
  • Musculoskeletal pain: eases strain‑related aches and soreness.
  • Acute postoperative pain: provides short‑term analgesia after surgical procedures.

How It Works

  • Ketoprofen lysine reversibly inhibits cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, decreasing the synthesis of prostaglandins that mediate inflammation, pain, and fever. By limiting prostaglandin production, it reduces vascular permeability, leukocyte infiltration, and nociceptor sensitization at sites of tissue injury.

Side Effects

Ketoprofen may cause a range of adverse reactions, from mild to severe.

Common Side Effects

  • Gastrointestinal upset: nausea, dyspepsia, or abdominal pain.
  • Headache or dizziness.
  • Mild skin rash or itching.
  • Elevated liver enzymes without clinical symptoms.
  • Fluid retention or mild edema.

Serious or Rare Side Effects

  • Gastrointestinal ulceration or bleeding.
  • Cardiovascular events such as myocardial infarction or stroke.
  • Acute renal failure or worsening of chronic kidney disease.
  • Severe skin reactions (Stevens‑Johnson syndrome, toxic epidermal necrolysis).
  • Hepatotoxicity with jaundice.
  • Anaphylactic or anaphylactoid reactions.

Precautions & Warnings

Before prescribing ketoprofen, clinicians should evaluate patient‑specific risk factors and monitor therapy.

  • Assess gastrointestinal risk: avoid in patients with a history of ulcer or bleeding.
  • Monitor renal function: use caution in those with impaired kidney function.
  • Avoid in known hypersensitivity to ketoprofen or other NSAIDs.
  • Use with caution in patients with cardiovascular disease or uncontrolled hypertension.
  • Review concomitant anticoagulant or antiplatelet therapy to reduce bleeding risk.
  • Store at room temperature: keep in the original pack, protect from moisture and direct sunlight.

Avoid Interactions

Ketoprofen can interact with several drug classes, requiring careful management.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased risk of serious bleeding.
  • Other NSAIDs or aspirin: additive gastrointestinal toxicity.
  • Corticosteroids: heightened ulcer risk.
  • Lithium: elevated serum lithium levels.
  • Methotrexate: reduced clearance leading to toxicity.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: possible reduction in renal function.
  • Diuretics: may impair kidney perfusion.
  • Selective serotonin reuptake inhibitors (SSRIs): increased bleeding tendency.
  • Antihypertensive agents: potential attenuation of blood pressure control.
  • Oral hypoglycemics: possible alteration of glucose control.

Frequently Asked Questions

Ketoprofene Sale Di Lisina Eg contains ketoprofen lysine, an NSAID that is commonly prescribed to relieve pain and reduce inflammation in rheumatoid arthritis, osteoarthritis, musculoskeletal injuries, and short‑term postoperative pain. It helps improve joint function and comfort in these inflammatory conditions.

Ketoprofen works by reversibly blocking the cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, which are essential for producing prostaglandins. Prostaglandins amplify inflammation, pain, and fever; by limiting their synthesis, ketoprofen reduces swelling, lowers pain signals, and helps control fever.

The exact dose and dosing schedule for Ketoprofene Sale Di Lisina Eg are determined by the prescribing clinician based on the patient’s condition, age, weight, and overall health. Healthcare professionals tailor the regimen to achieve optimal pain control while minimizing risk.

Ketoprofen is generally not recommended during pregnancy, especially in the third trimester, because of potential risks to the fetus and complications during labor. Limited data are available for breastfeeding; therefore, a healthcare provider should evaluate the benefits versus risks before use.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Ketoprofen is chemically related to other NSAIDs but has a slightly longer half‑life, which may allow less frequent dosing for some patients. Its potency in inhibiting COX enzymes is comparable to ibuprofen, yet individual response and tolerability can vary, making clinician choice dependent on patient‑specific factors.

Ketoprofene Sale Di Lisina Eg should be stored at room temperature, below 25 °C (77 °F). Keep the tablets in the original packaging, protect them from moisture, heat, and direct sunlight to maintain stability and potency.

The medication is taken orally, usually with a full glass of water. It can be taken with or without food, although taking it with food or an antacid may reduce gastrointestinal discomfort. Patients should follow the prescriber’s instructions regarding timing and frequency.

Serious risks include gastrointestinal bleeding or ulceration, cardiovascular events such as heart attack or stroke, severe kidney injury, liver toxicity, and rare but life‑threatening skin reactions like Stevens‑Johnson syndrome. Patients should be monitored for signs of these complications and seek immediate medical attention if they occur.

Ketoprofene Sale Di Lisina Eg should be avoided in individuals with known hypersensitivity to ketoprofen or any NSAID, active gastrointestinal ulcer or bleeding, severe heart failure, uncontrolled hypertension, or advanced renal or hepatic impairment. A healthcare professional should evaluate suitability before initiating therapy.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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