Product image of Ketoprofene Sale Di Lisina Ratiopharm (Ketoprofen) supplied by GNH India

Ketoprofene Sale Di Lisina Ratiopharm

Active Ingredient:
Ketoprofen
Origin:
EU

Ketoprofene Sale Di Lisina Ratiopharm (Ketoprofen)

Ketoprofen, the active ingredient in Ketoprofene Sale Di Lisina Ratiopharm, is a nonsteroidal anti-inflammatory drug (NSAID) presented as an oral tablet for oral use. It is indicated for the relief of mild to moderate pain, rheumatoid arthritis, osteoarthritis, musculoskeletal pain and other inflammatory conditions in adults.

GNH India supplies Ketoprofene Sale Di Lisina Ratiopharm as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Ratiopharm Gmbh

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Indications & Clinical Uses

Ketoprofen is an NSAID that reduces inflammation and pain in several musculoskeletal and rheumatic disorders.

  • Mild to moderate pain: provides analgesia for acute or chronic pain conditions.
  • Rheumatoid arthritis: helps control joint inflammation and swelling.
  • Osteoarthritis: reduces pain and improves joint function.
  • Musculoskeletal pain: alleviates discomfort from strains, sprains and overuse.
  • Inflammatory conditions: diminishes swelling in conditions such as bursitis or tendinitis.

How It Works

  • Ketoprofen exerts its effect by non‑selectively inhibiting cyclooxygenase‑1 (COX‑1) and cyclooxygenase‑2 (COX‑2) enzymes, which blocks the conversion of arachidonic acid to prostaglandins. The reduction in prostaglandin synthesis leads to decreased inflammation, pain perception, and fever.

Side Effects

Ketoprofen may cause a range of adverse reactions, from mild to severe.

Common Side Effects

  • Gastrointestinal discomfort: nausea, dyspepsia or abdominal pain.
  • Headache: mild to moderate intensity.
  • Dizziness or vertigo.
  • Skin rash or pruritus.
  • Elevated liver enzymes.
  • Fluid retention or peripheral edema.

Serious or Rare Side Effects

  • Gastrointestinal ulceration or bleeding.
  • Acute renal impairment or failure.
  • Severe hepatic injury.
  • Life‑threatening skin reactions such as Stevens‑Johnson syndrome.
  • Anaphylactic or severe allergic reactions.
  • Increased risk of cardiovascular thrombotic events.

Precautions & Warnings

When prescribing or dispensing ketoprofen, consider the following safety measures.

  • Assess gastrointestinal risk: avoid in patients with a history of ulcer disease.
  • Monitor renal function: use caution in those with impaired kidney function.
  • Use the lowest effective dose: limit duration to the shortest period necessary.
  • Avoid in known hypersensitivity to ketoprofen or other NSAIDs.
  • Caution with concomitant anticoagulants: increased bleeding risk.
  • Store at ambient temperature: keep in the original pack, protect from moisture.

Avoid Interactions

Ketoprofen can interact with several drug classes, requiring attention to avoid adverse outcomes.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): heightened bleeding risk.
  • Other NSAIDs or aspirin: additive gastrointestinal toxicity.
  • Corticosteroids: increased risk of ulceration and bleeding.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: possible reduction in renal function.
  • Diuretics: may enhance renal adverse effects.
  • Methotrexate: potential for increased toxicity.

Frequently Asked Questions

Ketoprofene Sale Di Lisina Ratiopharm contains ketoprofen, an NSAID that is used to relieve mild to moderate pain, reduce inflammation in rheumatoid arthritis and osteoarthritis, and treat musculoskeletal and other inflammatory conditions as directed by a healthcare professional.

Ketoprofen works by non‑selectively blocking the cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, which are essential for the production of prostaglandins. Lower prostaglandin levels result in reduced inflammation, pain signaling, and fever.

The appropriate dose of ketoprofen is determined by the prescribing clinician based on the patient’s condition, age, weight, renal and hepatic function, and other individual factors. Patients should follow the prescriber’s instructions and not adjust the dose on their own.

Ketoprofen is generally not recommended during pregnancy, especially in the third trimester, due to potential risks to the fetus. It also passes into breast milk, so breastfeeding mothers should consult their healthcare provider before using this medication.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Ketoprofen and ibuprofen belong to the same NSAID class and share a similar mechanism of COX inhibition. Ketoprofen is often considered more potent on a milligram‑per‑milligram basis, but both carry comparable risks of gastrointestinal, renal and cardiovascular side effects. Choice depends on clinical response, tolerability and physician preference.

Store the oral tablets at ambient temperature, preferably below 25 °C. Keep them in the original container, protect from moisture and direct sunlight, and ensure the packaging remains tightly closed until use.

The medication is taken orally, usually with a full glass of water. It may be taken with food or milk to reduce gastrointestinal discomfort, but patients should follow the specific instructions provided by their prescriber.

Serious risks include gastrointestinal bleeding or ulceration, severe renal impairment, hepatic injury, life‑threatening skin reactions such as Stevens‑Johnson syndrome, and increased cardiovascular events. Patients should be monitored for signs of these conditions and seek immediate medical attention if they occur.

Individuals with known hypersensitivity to ketoprofen or any NSAID, those with active gastrointestinal ulcer disease, severe renal or hepatic impairment, uncontrolled hypertension, or a history of cardiovascular thrombotic events should avoid using this medication unless specifically directed by a physician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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