Product image of Ketoprofene Sale Di Lisina Sandoz Gmbh (Ketoprofen) supplied by GNH India

Ketoprofene Sale Di Lisina Sandoz Gmbh

Active Ingredient:
Ketoprofen
Origin:
EU

Ketoprofene Sale Di Lisina Sandoz Gmbh (Ketoprofen)

Ketoprofen, the active ingredient in Ketoprofene Sale Di Lisina Sandoz Gmbh, is a nonsteroidal anti-inflammatory drug (NSAID) presented as an oral formulation for oral use. It treats pain and inflammation in adults, helping to relieve symptoms of musculoskeletal disorders and acute painful conditions.

GNH India supplies Ketoprofene Sale Di Lisina as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, ensuring consistent quality and regulatory compliance.

Manufacturer / TM Owner

Sandoz Gmbh

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Indications & Clinical Uses

  • Ketoprofen is an NSAID used to manage pain and inflammation associated with musculoskeletal and inflammatory conditions.
  • Rheumatoid arthritis: reduces joint pain, swelling and stiffness.
  • Osteoarthritis: alleviates chronic joint discomfort and improves mobility.
  • Acute pain: provides relief for postoperative, dental or musculoskeletal pain.
  • Ankylosing spondylitis: diminishes spinal inflammation and associated pain.

How It Works

  • Ketoprofen inhibits cyclooxygenase (COX‑1 and COX‑2) enzymes, which blocks the conversion of arachidonic acid to prostaglandins. By reducing prostaglandin synthesis, it lowers inflammation, pain signaling, and fever responses at the site of tissue injury, producing its analgesic and anti‑inflammatory effects.

Side Effects

Ketoprofen may cause a range of adverse reactions, from mild to serious.

Common Side Effects

  • Gastrointestinal discomfort such as nausea, dyspepsia or abdominal pain.
  • Headache or dizziness.
  • Mild skin rash or itching.

Serious or Rare Side Effects

  • Gastrointestinal ulceration or bleeding.
  • Severe hypersensitivity reactions, including Stevens‑Johnson syndrome.
  • Renal impairment or sudden loss of kidney function.
  • Elevated liver enzymes indicating hepatic injury.

Precautions & Warnings

  • Ketoprofen should be used with caution in specific clinical situations.
  • Cardiovascular risk: avoid in patients with uncontrolled hypertension or recent myocardial infarction.
  • Gastrointestinal safety: use gastro‑protective agents in patients with a history of ulcers.
  • Renal function: monitor kidney parameters in those with pre‑existing renal disease.
  • Pregnancy and lactation: assess risk‑benefit before prescribing to pregnant or nursing women.
  • Store below 25°C: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Ketoprofen can interact with several medicines, requiring careful management.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased risk of serious bleeding.
  • Other NSAIDs or aspirin: heightened gastrointestinal toxicity.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: may reduce renal perfusion, especially in volume‑depleted patients.
  • Lithium: NSAIDs can raise lithium serum levels, risking toxicity.
  • Methotrexate: reduced clearance may lead to enhanced toxicity.

Frequently Asked Questions

Ketoprofene Sale Di Lisina contains ketoprofen, an NSAID indicated for the relief of pain and inflammation associated with rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, and acute musculoskeletal or postoperative pain. It helps reduce swelling, stiffness, and discomfort in these conditions.

Ketoprofen works by inhibiting the cyclooxygenase enzymes COX‑1 and COX‑2, which are essential for the production of prostaglandins. Lower prostaglandin levels decrease inflammation, pain signaling, and fever, providing analgesic and anti‑inflammatory effects at the site of injury.

The specific dose and dosing schedule for Ketoprofene Sale Di Lisina are determined by the prescribing healthcare professional based on the patient’s condition, age, weight, and renal or hepatic function. Patients should follow the prescriber’s instructions and not adjust the dose on their own.

Ketoprofen is generally avoided during the third trimester of pregnancy because of potential risks to the fetus and labor. Safety during early pregnancy and lactation is not well established, so clinicians weigh benefits against possible risks before prescribing to pregnant or nursing mothers.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Ketoprofen has a similar mechanism to ibuprofen but often provides longer‑lasting analgesia and may be more potent on a milligram‑per‑milligram basis. However, its gastrointestinal and cardiovascular risk profile is comparable, so the choice depends on clinical response, tolerability, and individual patient risk factors.

Ketoprofene Sale Di Lisina should be stored below 25 °C in a dry place. Keep the tablets in the original packaging, protect them from moisture and direct sunlight, and ensure they are out of reach of children.

The product is taken orally, usually with a full glass of water. It can be taken with or without food, although taking it with meals may reduce gastrointestinal irritation. Patients should swallow the tablets whole and not crush or chew them unless instructed otherwise.

Serious risks include gastrointestinal bleeding or ulceration, severe allergic reactions such as Stevens‑Johnson syndrome, renal impairment, and increased cardiovascular events in susceptible individuals. Patients should be monitored for signs of bleeding, rash, sudden kidney problems, or chest pain, and seek medical attention promptly if they occur.

Ketoprofen is contraindicated in patients with known hypersensitivity to ketoprofen or other NSAIDs, active gastrointestinal ulceration or bleeding, severe heart failure, and in the third trimester of pregnancy. Caution is also advised for those with impaired renal or hepatic function, and it should be avoided in children unless specifically prescribed.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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