Product image of Ketorolac S.A.L.F. (Ketorolac Trometamol) supplied by GNH India

Ketorolac S.A.L.F.

Active Ingredient:
Ketorolac Trometamol
Origin:
EU

Ketorolac S.A.L.F. (Ketorolac Trometamol)

Ketorolac Trometamol, the active ingredient in Ketorolac S.A.L.F., is a nonsteroidal anti-inflammatory drug presented as an injectable solution for intramuscular and intravenous use. It is used for short‑term management of moderate to severe acute pain, including post‑operative pain, in adult patients.

GNH India supplies Ketorolac S.A.L.F. as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, transplant centres, oncology centres, pharmacies and clinics worldwide.

Manufacturer / TM Owner

S.A.L.F. Spa Laboratorio Farmacologico

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

  • Ketorolac Trometamol is an NSAID used to manage pain through cyclooxygenase inhibition.
  • Acute postoperative pain: provides short‑term relief of moderate to severe pain after surgery.
  • Acute musculoskeletal pain: reduces pain associated with injuries or strains.
  • Renal colic: alleviates severe flank pain caused by kidney stones.

How It Works

  • Ketorolac Trometamol reversibly inhibits both cyclooxygenase‑1 (COX‑1) and cyclooxygenase‑2 (COX‑2) enzymes, leading to a decrease in prostaglandin synthesis. The reduced prostaglandin levels diminish inflammation, lower pain signaling, and produce antipyretic effects, resulting in analgesic and anti‑inflammatory activity.

Side Effects

Ketorolac may cause a range of adverse reactions, from mild to severe.

Common Side Effects

  • Gastrointestinal discomfort: nausea, dyspepsia, or abdominal pain.
  • Headache: mild to moderate intensity.
  • Dizziness: transient sensation of light‑headedness.
  • Nausea: occasional feeling of queasiness.
  • Injection site pain: local irritation after intramuscular or intravenous administration.
  • Mild renal function changes: temporary increase in serum creatinine.

Serious or Rare Side Effects

  • Severe gastrointestinal bleeding or ulceration.
  • Renal impairment or failure, especially with prolonged use.
  • Anaphylactic or severe hypersensitivity reactions.
  • Platelet dysfunction leading to abnormal bleeding.
  • Hepatotoxicity: elevated liver enzymes.
  • Cardiovascular events such as myocardial infarction or stroke.

Precautions & Warnings

  • Ketorolac requires careful assessment of patient risk factors before use.
  • Renal function: avoid in patients with severe renal impairment.
  • Bleeding risk: use cautiously in patients with coagulopathy or on anticoagulants.
  • Gastrointestinal ulcer: contraindicated in active ulcer disease.
  • Pregnancy: avoid especially in the third trimester due to fetal risk.
  • Elderly: monitor for renal and central nervous system effects.
  • Store at ambient temperature: keep in original container, protect from light and moisture.

Avoid Interactions

Ketorolac can interact with several drug classes, requiring monitoring or avoidance.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased risk of serious bleeding.
  • Other NSAIDs or aspirin: additive gastrointestinal toxicity.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors: may reduce renal function when combined.
  • Diuretics: heightened risk of renal impairment.
  • Lithium: potential increase in lithium serum concentrations.

Frequently Asked Questions

Ketorolac S.A.L.F. is an injectable nonsteroidal anti‑inflammatory drug indicated for the short‑term management of moderate to severe acute pain, such as postoperative pain or pain from renal colic, in adult patients.

Ketorolac Trometamol works by reversibly inhibiting the cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, which reduces the synthesis of prostaglandins. Lower prostaglandin levels diminish inflammation and pain signaling, providing analgesic and anti‑inflammatory effects.

The specific dose and duration are determined by the prescribing clinician based on the patient’s condition, weight, renal function, and treatment setting. Ketorolac is typically administered as a single or limited‑course injection under medical supervision.

Ketorolac is generally avoided during pregnancy, especially in the third trimester, due to potential fetal risks. Limited data exist for breastfeeding; therefore, clinicians usually consider alternative analgesics unless the benefit outweighs the risk.

To place an order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if needed), and import documentation.

Ketorolac is distinguished by its potent analgesic effect, often comparable to opioid analgesics for short‑term use, whereas many other NSAIDs provide milder pain relief. However, its risk profile for gastrointestinal bleeding and renal effects is higher, so it is reserved for brief treatment periods.

Ketorolac S.A.L.F. should be stored at ambient temperature, below 25 °C, in its original packaging. Protect the solution from light, moisture, and extreme temperatures. Do not freeze or shake the vial before use.

The product is supplied as a sterile injectable solution for intramuscular or intravenous administration. The route, injection site, and infusion rate are determined by the healthcare professional based on clinical guidelines and patient needs.

The most serious risks include severe gastrointestinal bleeding or ulceration, acute renal failure, severe hypersensitivity reactions such as anaphylaxis, and platelet dysfunction leading to abnormal bleeding. Patients should be monitored closely for these events, especially when used with other high‑risk medications.

Ketorolac should be avoided in patients with known hypersensitivity to ketorolac or other NSAIDs, active gastrointestinal ulcer disease, severe renal impairment, significant bleeding disorders, and in the third trimester of pregnancy. Caution is also advised for the elderly and those on anticoagulants.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.