Product image of Ketorolac Trometamol Misom (Ketorolac Trometamol) supplied by GNH India

Ketorolac Trometamol Misom

Active Ingredient:
Ketorolac Trometamol
Origin:
EU

Ketorolac Trometamol Misom (Ketorolac Trometamol)

Ketorolac Trometamol, the active ingredient in Ketorolac Trometamol Misom, is a nonsteroidal anti‑inflammatory drug (NSAID) presented as an ophthalmic solution for ocular use. It is employed to reduce inflammation and relieve pain following eye surgery or other ocular procedures.

GNH India supplies Ketorolac Trometamol Misom as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, transplant centres, oncology centres, pharmacies and clinics worldwide, ensuring quality and regulatory compliance across global markets.

Manufacturer / TM Owner

Misom Labs Limited

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Indications & Clinical Uses

Ketorolac Trometamol is used in ophthalmology to manage inflammation and pain associated with surgical and non‑surgical ocular conditions.

  • Post‑operative ocular inflammation: reduces swelling and redness after eye surgery.
  • Ocular pain: provides rapid relief of pain following procedures or trauma.
  • Inflammation following eye surgery: controls inflammatory response to maintain visual clarity.

How It Works

  • Ketorolac Trometamol reversibly inhibits cyclooxygenase‑1 and cyclooxygenase‑2 enzymes in ocular tissues, decreasing prostaglandin synthesis. The reduction in prostaglandins limits the inflammatory cascade, leading to diminished edema, hyperemia, and pain at the site of ocular injury or surgery.

Side Effects

Ketorolac Trometamol may cause local ocular reactions and, rarely, serious ocular complications.

Common Side Effects

  • Burning or stinging sensation upon instillation.
  • Transient blurred vision.
  • Foreign body sensation.
  • Mild conjunctival hyperemia.
  • Increased tearing.
  • Temporary eyelid edema.

Serious or Rare Side Effects

  • Corneal ulceration or perforation.
  • Severe allergic reaction, including anaphylaxis.
  • Significant increase in intra‑ocular pressure.
  • Persistent corneal edema.
  • Stevens‑Johnson syndrome or toxic epidermal necrolysis.
  • Vision loss.

Precautions & Warnings

When using Ketorolac Trometamol, consider the following precautions.

  • Contraindication: avoid in patients with known hypersensitivity to ketorolac or other NSAIDs.
  • Caution: use carefully in patients with pre‑existing corneal disorders.
  • Avoid: concurrent use with other topical NSAIDs to reduce risk of additive toxicity.
  • Monitor: watch for signs of increased intra‑ocular pressure during prolonged therapy.
  • Pregnancy: safety not established; use only if clearly needed.
  • Store at ambient temperature: keep in original container, protect from light and moisture.

Avoid Interactions

Ketorolac Trometamol can interact with other medications; some require avoidance while others need monitoring.

Major Interactions (Avoid)

  • Concurrent systemic NSAIDs: increased risk of systemic adverse effects.
  • Topical corticosteroids: may reduce anti‑inflammatory efficacy.
  • Anticoagulants: heightened bleeding risk if systemic absorption occurs.
  • Contact lens wear: may increase drug retention and irritation.
  • Other ocular medications: may cause formulation incompatibility.

Moderate Interactions (Monitor Closely)

  • Beta‑blocker eye drops: possible additive ocular hypotensive effect.
  • Anticholinergic eye drops: may affect pupil response.
  • Systemic COX‑2 inhibitors: monitor for additive renal effects.

Frequently Asked Questions

Ketorolac Trometamol Misom is an ophthalmic NSAID indicated for the treatment of post‑operative ocular inflammation, ocular pain, and inflammation that follows eye surgery. It helps to reduce swelling, redness, and discomfort in the treated eye.

The drug reversibly blocks cyclooxygenase‑1 and cyclooxygenase‑2 enzymes in eye tissues, which lowers prostaglandin production. Reduced prostaglandins diminish the inflammatory response, leading to less pain, edema, and hyperemia in the ocular area.

The specific dosing regimen for Ketorolac Trometamol is determined by the prescribing clinician based on the patient’s condition, severity of inflammation, and response to therapy. Only a qualified healthcare professional should set the dose.

Safety data for Ketorolac Trometamol during pregnancy and lactation are limited. It should be used only if the potential benefit justifies any possible risk to the fetus or infant, and the decision must be made by the treating physician.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Ketorolac Trometamol is a potent COX‑1/COX‑2 inhibitor with a rapid onset of action, making it effective for acute post‑surgical inflammation. Compared with some other ocular NSAIDs, it may provide stronger pain relief but shares a similar safety profile, requiring careful monitoring for ocular surface effects.

Store the ophthalmic solution at ambient temperature, preferably below 25 °C, in its original container. Protect it from direct light and moisture, and keep the cap tightly closed when not in use to maintain sterility.

Ketorolac Trometamol is applied as eye drops directly onto the affected eye(s) according to the prescribing information. The patient should wash their hands before use, avoid touching the tip of the bottle to the eye or any surface, and follow the frequency recommended by the clinician.

Serious adverse events include corneal ulceration or perforation, severe allergic reactions such as anaphylaxis, significant increases in intra‑ocular pressure, and rare systemic hypersensitivity syndromes like Stevens‑Johnson syndrome. Any sudden vision changes or severe eye pain should prompt immediate medical evaluation.

Patients with known hypersensitivity to ketorolac, other NSAIDs, or any component of the formulation should avoid this product. It is also contraindicated in individuals with active corneal infections, severe ocular surface disease, or those who have had recent corneal surgery unless specifically directed by an eye specialist.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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