Product image of Ketorolac Trometamol S.A.L.F. (Ketorolac Trometamol) supplied by GNH India

Ketorolac Trometamol S.A.L.F.

Active Ingredient:
Ketorolac Trometamol
Origin:
EU

Ketorolac Trometamol S.A.L.F. (Ketorolac Trometamol)

Ketorolac Trometamol, the active ingredient in Ketorolac Trometamol S.A.L.F., is a nonsteroidal anti-inflammatory drug (NSAID) presented as an injectable solution for intramuscular and intravenous use. It is employed for short‑term management of moderate to severe acute pain in adult patients.

GNH India supplies Ketorolac Trometamol S.A.L.F. as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides regulatory documentation for global distribution.

Manufacturer / TM Owner

S.A.L.F. Spa Laboratorio Farmacologico

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Ketorolac Trometamol is an NSAID indicated for short‑term relief of moderate to severe acute pain across several clinical settings.

  • Post‑operative pain: provides effective analgesia following surgical procedures
  • Renal colic: reduces pain associated with kidney stone passage
  • Dental pain: controls discomfort after dental extractions
  • Musculoskeletal injury: alleviates pain from sprains, strains, and fractures

How It Works

  • Ketorolac Trometamol exerts its analgesic and anti‑inflammatory effects by non‑selectively inhibiting cyclooxygenase‑1 and cyclooxygenase‑2 enzymes. This blockade reduces the synthesis of prostaglandins, which are mediators of inflammation, pain, and fever. The resulting decrease in prostaglandin levels diminishes peripheral sensitization of nociceptors and limits the inflammatory response, providing rapid pain relief.

Side Effects

Ketorolac Trometamol may cause a range of adverse reactions, varying from mild to severe.

Common Side Effects

  • Nausea
  • Headache
  • Dizziness
  • Injection site pain

Serious or Rare Side Effects

  • Gastrointestinal bleeding
  • Severe allergic reaction (anaphylaxis)
  • Renal impairment

Precautions & Warnings

When prescribing Ketorolac Trometamol, clinicians should observe several precautionary measures to minimize risk.

  • Assess renal function before initiating therapy: avoid use in severe renal impairment.
  • Avoid in patients with active peptic ulcer disease or gastrointestinal bleeding: increased risk of ulceration.
  • Use the lowest effective dose for the shortest duration: typically not exceeding five days.
  • Monitor for signs of bleeding: watch for hematemesis, melena, or bruising.
  • Avoid concomitant use with other NSAIDs or anticoagulants: heightened risk of adverse events.
  • Store at ambient temperature: keep in original container, protect from moisture and light.

Avoid Interactions

Ketorolac Trometamol can interact with several medicines, altering its safety profile or efficacy.

Major Interactions (Avoid)

  • Concurrent use with anticoagulants (e.g., warfarin, heparin): may markedly increase bleeding risk.
  • Combination with other NSAIDs or COX‑2 inhibitors: can amplify gastrointestinal toxicity.

Moderate Interactions (Monitor Closely)

  • Co‑administration with ACE inhibitors or diuretics: may reduce renal function.
  • Use with selective serotonin reuptake inhibitors (SSRIs) or serotonin‑norepinephrine reuptake inhibitors (SNRIs): may elevate bleeding tendency.
  • Concomitant lithium therapy: ketorolac may raise lithium serum concentrations.

Frequently Asked Questions

Ketorolac Trometamol is used for the short‑term relief of moderate to severe acute pain. It is commonly prescribed after surgery, for renal colic caused by kidney stones, following dental procedures, and for musculoskeletal injuries such as sprains or fractures where rapid analgesia is required.

The drug works by non‑selectively inhibiting the cyclooxygenase‑1 and cyclooxygenase‑2 enzymes. This inhibition blocks the conversion of arachidonic acid to prostaglandins, reducing the inflammatory mediators that cause pain, swelling, and fever, thereby providing effective analgesia.

The exact dose of Ketorolac Trometamol is determined by the prescribing clinician based on the patient’s condition, age, renal function, and route of administration. Typical dosing regimens range from a single dose to a short course, but the prescriber sets the precise amount and schedule.

Data on the use of Ketorolac Trometamol during pregnancy and lactation are limited, and the drug is generally avoided, especially in the third trimester, because of potential risks to the fetus and newborn. Healthcare providers should weigh benefits against possible hazards before prescribing to pregnant or nursing women.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, confirming trade or institutional credentials before providing pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.

Ketorolac Trometamol is considered one of the more potent NSAIDs for short‑term pain control and is available only for injectable use, allowing rapid onset. Compared with oral NSAIDs, it provides stronger analgesia but carries a higher risk of gastrointestinal and renal adverse effects, so its use is limited to brief periods.

The product should be stored at ambient temperature, preferably below 25 °C. Keep the vials in their original packaging, protect them from moisture and direct light, and ensure they are not frozen. Follow standard aseptic handling procedures when preparing for intramuscular or intravenous administration.

Ketorolac Trometamol is supplied as an injectable solution and may be given either intramuscularly or intravenously. The route, injection site, and rate of administration are determined by the prescribing clinician, who will also monitor the patient for any immediate adverse reactions during and after the injection.

Serious risks include gastrointestinal bleeding or ulceration, severe allergic reactions such as anaphylaxis, and renal impairment, especially in patients with pre‑existing kidney disease. Cardiovascular events such as myocardial infarction or stroke can also occur, particularly with prolonged use or in high‑risk individuals.

Ketorolac Trometamol should be avoided in patients with known hypersensitivity to ketorolac or other NSAIDs, active peptic ulcer disease, significant renal impairment, uncontrolled hypertension, and those receiving anticoagulant therapy where bleeding risk is high. It is also contraindicated in the third trimester of pregnancy.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.