Product image of Ketosteril (L-Lysine Acetate, L-Tryptophan, L-Histidine, L-Threonine, L-Tyrosine, Keto-Isoleucine Calcium, Keto-) supplied by GNH India

Ketosteril

Active Ingredient:
L-Lysine Acetate, L-Tryptophan, L-Histidine, L-Threonine, L-Tyrosine, Keto-Isoleucine Calcium, Keto-
Origin:
EU

Ketosteril (L-Lysine Acetate, L-Tryptophan, L-Histidine, L-Threonine, L-Tyrosine, Keto-Isoleucine Calcium, Keto-)

L‑Lysine Acetate, the active ingredient in Ketosteril, is an amino acid supplement presented as an oral formulation for use in patients with chronic kidney disease and related renal conditions. It supplies essential amino acids and keto‑analogues to help reduce nitrogen waste and support protein synthesis.

GNH India supplies Ketosteril as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, transplant centres, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Fresenius Kabi Deutschland Gmbh

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Indications & Clinical Uses

Ketosteril is used in renal nutrition to manage metabolic complications of chronic kidney disease and related conditions.

  • Chronic kidney disease: helps lower nitrogenous waste accumulation and supports nutritional status.
  • Renal failure: provides essential amino acids and keto‑analogues to reduce protein catabolism.
  • Dialysis patients: assists in maintaining protein balance while minimizing nitrogen load.

How It Works

  • Ketosteril delivers a mixture of essential amino acids and their keto‑analogues, which are transaminated in the body to form complete proteins. By supplying these precursors, the product reduces the need for dietary protein, thereby decreasing nitrogenous waste production and alleviating the metabolic burden on impaired kidneys.

Side Effects

Ketosteril may cause adverse reactions, which are categorized by frequency.

Common Side Effects

  • Nausea: mild to moderate upset stomach.
  • Vomiting: occasional episodes after dosing.
  • Loss of appetite: reduced desire to eat.
  • Headache: transient mild headache.

Serious or Rare Side Effects

  • Hyperkalemia: elevated blood potassium levels.
  • Metabolic acidosis: abnormal acid‑base balance.
  • Allergic reactions: rash, angioedema, or anaphylaxis.
  • Severe gastrointestinal bleeding: uncommon but serious.

Precautions & Warnings

Ketosteril requires careful monitoring in specific clinical situations.

  • Monitor renal function: assess kidney parameters regularly.
  • Adjust dose in severe renal impairment: follow prescriber guidance.
  • Avoid in patients with known hypersensitivity to any component.
  • Use caution during pregnancy: benefits must outweigh potential risks.
  • Store at room temperature: keep in the original pack, protect from moisture.

Avoid Interactions

Ketosteril can interact with other medicines and supplements.

Major Interactions (Avoid)

  • High‑protein dietary supplements: may counteract nitrogen reduction.
  • Concurrent nephrotoxic drugs: increase renal stress.
  • Potassium‑sparing diuretics: risk of hyperkalemia.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: monitor potassium and renal function.
  • Calcium‑containing antacids: may affect absorption of keto‑analogues.
  • Liver enzyme inducers: could alter metabolism of amino acid components.

Frequently Asked Questions

Ketosteril is an oral amino acid supplement prescribed to patients with chronic kidney disease, renal failure, or those undergoing dialysis. It provides essential amino acids and keto‑analogues to help reduce nitrogen waste and support protein synthesis, thereby assisting in renal nutrition management.

L‑Lysine Acetate, together with other amino acids and keto‑analogues in Ketosteril, supplies building blocks that the body can convert into complete proteins. This reduces the need for dietary protein, decreasing nitrogenous waste production and easing the metabolic load on compromised kidneys.

The dose of Ketosteril is individualized and set by the prescribing healthcare professional based on the patient’s renal function, nutritional status, and overall treatment plan. Patients should follow the specific instructions provided by their doctor or pharmacist.

Safety data for Ketosteril in pregnancy and lactation are limited. It should only be used if the potential benefit to the mother outweighs any possible risk to the fetus or infant, and this decision must be made by a qualified healthcare provider.

To order Ketosteril, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India supplies hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Ketosteril uniquely combines essential amino acids with keto‑analogues, offering a balanced approach to reduce nitrogen waste while providing necessary protein precursors. Compared with plain protein supplements, it allows lower dietary protein intake without compromising nutritional status, which is advantageous for patients with limited kidney function.

Ketosteril should be stored at room temperature, below 25 °C, in its original packaging. Keep the product away from moisture and direct sunlight to maintain its stability and potency throughout its shelf life.

Ketosteril is taken orally, usually with meals as directed by a healthcare professional. The tablets or capsules should be swallowed whole with water unless otherwise instructed by the prescriber.

Serious risks include hyperkalemia, metabolic acidosis, severe allergic reactions such as anaphylaxis, and rare cases of gastrointestinal bleeding. Patients should be monitored regularly for these conditions, especially if they have pre‑existing risk factors.

Ketosteril should be avoided in individuals with known hypersensitivity to any of its components, in patients receiving high‑protein supplements that negate its purpose, and in those taking nephrotoxic medications without close medical supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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