Product image of Ketosteril (L-Lysine Acetate, L-Tryptophan, L-Histidine, L-Threonine, L-Tyrosine, Keto-Isoleucine Calcium, Keto-) supplied by GNH India

Ketosteril

Active Ingredient:
L-Lysine Acetate, L-Tryptophan, L-Histidine, L-Threonine, L-Tyrosine, Keto-Isoleucine Calcium, Keto-
Origin:
EU

Ketosteril (L-Lysine Acetate, L-Tryptophan, L-Histidine, L-Threonine, L-Tyrosine, Keto-Isoleucine Calcium, Keto-)

Keto-analogues of essential amino acids, the active ingredients in Ketosteril, are an amino acid supplement presented as an oral formulation for oral use. It is used to support nutritional management in patients with chronic kidney disease and renal failure by reducing nitrogen load.
GNH India supplies Ketosteril as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, transplant centres and pharmacies worldwide.

Manufacturer / TM Owner

Fresenius Kabi Deutschland Gmbh

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Indications & Clinical Uses

  • Ketosteril is used in renal nutrition to address metabolic challenges associated with reduced kidney function.
  • Chronic kidney disease: helps lower nitrogen waste production and supports protein nutrition.
  • Renal failure: provides essential amino acid precursors while minimizing uremic toxin accumulation.
  • Dietary management of reduced renal function: assists in maintaining adequate nutrition with reduced nitrogen intake.

How It Works

  • Ketosteril supplies keto‑analogues of essential amino acids that are transaminated in the body to form the corresponding amino acids. This process consumes nitrogen, thereby decreasing the generation of nitrogenous waste products and reducing the uremic load in patients with impaired renal function.

Side Effects

Common Side Effects

  • Nausea or vomiting
  • Loss of appetite
  • Abdominal discomfort or diarrhea
  • Headache

Serious or Rare Side Effects

  • Hyperkalemia or metabolic acidosis
  • Severe allergic reactions including rash or angioedema
  • Hepatic dysfunction
  • Hyperphosphatemia

Precautions & Warnings

When using Ketosteril, consider the following precautions:

  • Renal function monitoring: assess serum creatinine and urea regularly.
  • Electrolyte balance: watch potassium and phosphate levels.
  • Protein intake adjustment: coordinate with dietitian to avoid excess protein.
  • Pregnancy and lactation: use only if clearly needed and prescribed.
  • Pediatric use: safety not established, use with caution.
  • Store at ambient temperature: keep in original container, protect from moisture and direct sunlight.

Avoid Interactions

Ketosteril may interact with other agents affecting renal function or nitrogen balance.

Major Interactions (Avoid)

  • High‑protein dietary supplements: may counteract nitrogen‑sparing effect.
  • Concurrent use of other keto‑analogue formulations: risk of excess amino‑acid precursors.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: monitor potassium and renal parameters.
  • NSAIDs: may impair renal clearance, increase nitrogen load.
  • Calcium‑containing antacids: could affect absorption of calcium‑bound keto‑analogues.

Frequently Asked Questions

Ketosteril is an oral amino‑acid supplement that provides keto‑analogues of essential amino acids. It is used to support nutritional management in patients with chronic kidney disease or renal failure by reducing nitrogen waste and helping maintain protein balance.

The keto‑analogues in Ketosteril are transaminated in the body to become the corresponding essential amino acids. This conversion consumes nitrogen, thereby lowering the production of nitrogenous waste products and decreasing the uremic burden in individuals with impaired renal function.

The dose of Ketosteril is individualized. A qualified prescriber determines the appropriate amount based on the patient’s renal status, nutritional needs, and overall treatment plan. No standard dosing can be provided without professional medical guidance.

Safety data for Ketosteril in pregnancy and lactation are limited. It should only be used if the potential benefit justifies the potential risk and after a thorough evaluation by the treating physician.

To place an order, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Ketosteril uniquely supplies keto‑analogues that are converted to essential amino acids, directly reducing nitrogen load. Other renal supplements may provide standard amino acids or protein‑restricted formulas, but they do not offer the same nitrogen‑sparing transamination pathway.

Ketosteril should be stored at ambient temperature, below 25 °C, in its original packaging. Protect it from moisture, direct sunlight and extreme temperature fluctuations to maintain product stability.

Ketosteril is taken orally, usually with meals, as directed by the prescribing clinician. The exact timing and frequency depend on the individual’s nutritional plan and renal management strategy.

Serious risks include hyperkalemia, metabolic acidosis, severe allergic reactions, hepatic dysfunction, and hyperphosphatemia. Patients should be monitored regularly for these conditions, especially if they have pre‑existing electrolyte or liver abnormalities.

Ketosteril is contraindicated in patients with known hypersensitivity to any of its components, those with uncontrolled hyperkalemia or severe metabolic acidosis, and individuals for whom a low‑protein, low‑nitrogen diet is not indicated. Clinical judgment is required for each case.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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