Product image of Ketosteril (L-Lysine Acetate, L-Tryptophan, L-Histidine, L-Threonine, L-Tyrosine, Keto-Isoleucine Calcium, Keto-) supplied by GNH India

Ketosteril

Active Ingredient:
L-Lysine Acetate, L-Tryptophan, L-Histidine, L-Threonine, L-Tyrosine, Keto-Isoleucine Calcium, Keto-
Origin:
EU

Ketosteril (L-Lysine Acetate, L-Tryptophan, L-Histidine, L-Threonine, L-Tyrosine, Keto-Isoleucine Calcium, Keto-)

L‑Lysine Acetate, the active ingredient in Ketosteril, is a keto‑analogue of essential amino acids presented as various strengths/tablet for oral use. It supports protein metabolism and reduces nitrogen load in patients with chronic kidney disease and other forms of renal insufficiency.

GNH India supplies Ketosteril as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, transplant centres and pharmacies worldwide.

Manufacturer / TM Owner

Fresenius Kabi Ab

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Ketosteril is used in the management of renal conditions where protein intake must be restricted.

  • Chronic kidney disease: helps maintain nutritional status while limiting nitrogen accumulation.
  • Renal failure: provides keto‑analogues that are converted to essential amino acids, reducing uremic toxins.
  • Dietary management of protein‑restricted diets: supports adequate amino acid supply without increasing nitrogen load.

How It Works

  • Ketosteril supplies keto‑analogues of essential amino acids that are transaminated in the body to form the corresponding essential amino acids. This process bypasses the need for nitrogen‑containing substrates, thereby lowering the nitrogen burden and supporting protein synthesis in patients with impaired renal function.

Side Effects

Ketosteril may cause adverse reactions, most of which are mild and reversible.

Common Side Effects

  • Nausea: mild to moderate stomach upset.
  • Vomiting: occasional episodes, especially when taken on an empty stomach.
  • Loss of appetite: reduced desire to eat.
  • Abdominal discomfort: mild cramps or bloating.
  • Headache: transient mild headache.
  • Dizziness: occasional light‑headedness.

Serious or Rare Side Effects

  • Hyperkalemia: elevated blood potassium levels.
  • Metabolic acidosis: significant shift in acid‑base balance.
  • Allergic reactions: rash, itching, or swelling.
  • Severe skin rash: Stevens‑Johnson‑type reactions.
  • Hepatic dysfunction: abnormal liver enzymes.
  • Electrolyte imbalance: disturbances in sodium, calcium or phosphate levels.

Precautions & Warnings

When prescribing Ketosteril, clinicians should consider several safety measures.

  • Monitor renal function: assess glomerular filtration rate regularly.
  • Adjust protein intake: coordinate with dietitian to maintain low‑protein diet.
  • Review electrolyte levels: especially potassium and phosphate.
  • Avoid in severe hepatic impairment: liver dysfunction may affect transamination.
  • Use caution in pregnancy: limited data, weigh benefits against potential risks.
  • Store at ambient temperature: keep in original container, protect from moisture and direct sunlight.

Avoid Interactions

Ketosteril can interact with other agents that affect nitrogen balance or electrolyte status.

Major Interactions (Avoid)

  • High‑protein supplements: may negate the nitrogen‑sparing effect.
  • Sodium bicarbonate excess: can exacerbate metabolic alkalosis.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: monitor potassium and renal function.
  • Potassium‑sparing diuretics: risk of hyperkalemia.
  • Phosphate binders: may affect phosphate balance.
  • Vitamin D analogues: watch for calcium‑phosphate product changes.
  • Other keto‑analogues: avoid cumulative dosing without specialist guidance.

Frequently Asked Questions

Ketosteril is a renal nutrition supplement that provides keto‑analogues of essential amino acids. It is used to support protein metabolism and reduce nitrogen load in patients with chronic kidney disease, renal failure, or those following a protein‑restricted diet.

L‑Lysine Acetate, together with other keto‑analogues in Ketosteril, is transaminated in the body to become the corresponding essential amino acid. This conversion supplies needed amino acids without adding nitrogen, helping to lower uremic toxins in impaired kidney function.

The dosage of Ketosteril is individualized. The prescribing clinician determines the appropriate amount based on the patient’s renal function, dietary protein restriction, and overall nutritional needs.

Safety data for Ketosteril in pregnancy and lactation are limited. It should only be used if the potential benefit justifies any possible risk to the fetus or infant, and the decision must be made by the treating physician.

To order Ketosteril, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Ketosteril is a keto‑analogue formulation that directly supplies nitrogen‑free precursors of essential amino acids, whereas some alternatives provide standard amino acid mixtures. The keto‑analogue approach can better limit nitrogen accumulation in advanced renal disease, but choice depends on individual patient needs and clinician preference.

Ketosteril tablets should be stored at ambient temperature, below 25 °C, in the original packaging. Keep the product away from moisture, direct sunlight and excessive heat to maintain stability.

Ketosteril is taken orally, usually with meals, as directed by the prescribing healthcare professional. The tablets are swallowed whole with water and should be incorporated into the patient’s overall renal diet plan.

Serious risks, though rare, include hyperkalemia, metabolic acidosis, severe allergic reactions such as Stevens‑Johnson syndrome, hepatic dysfunction, and significant electrolyte disturbances. Patients should be monitored regularly for these potential events.

Ketosteril should be avoided in patients with severe hepatic impairment, known hypersensitivity to any component, or in those where a high‑protein diet is required. Contra‑indications should be confirmed by the treating physician before initiation.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Related Products

Other formulations containing L-Lysine Acetate, L-Tryptophan, L-Histidine, L-Threonine, L-Tyrosine, Keto-Isoleucine Calcium, Keto-

A

A
A

A
A

A
A

A

Browse all products →

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Regulatory recognitions

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.

SGS GSDP Certification

GSDP Compliant from SGS

URS ISO 9001

URS ISO 9001 Certification

FDA Maharashtra

Licensed by FDA Maharashtra

IEC License DGFT

IEC License issued by DGFT