Ketotifen Stulln Zonder Conserveermiddel 0,25 Mg/Ml Oogdruppels Pharma Stulln (Ketotifen)

Ketotifen is an ocular antihistamine used to manage allergic eye conditions.

• Allergic conjunctivitis: reduces redness, swelling and itching caused by allergen exposure.
• Ocular itching: relieves persistent eye‑itch associated with seasonal or perennial allergies.
• Eye allergy symptoms: alleviates tearing, burning and discomfort during allergic episodes.

• Ketotifen acts as a selective antagonist of histamine H1 receptors on ocular tissues, preventing histamine‑mediated vasodilation and sensory nerve activation. It also stabilizes mast cells, inhibiting the release of inflammatory mediators such as prostaglandins and leukotrienes, thereby reducing allergic inflammation in the eye.

Ketotifen eye drops may cause a range of ocular and systemic reactions.

Common Side Effects

• Burning or stinging sensation upon instillation.
• Transient blurred vision lasting a few minutes.
• Mild eye irritation or redness.
• Temporary tearing or discharge.
• Mild headache.
• Slight eyelid swelling.

Serious or Rare Side Effects

• Severe allergic reaction (anaphylaxis) with swelling of the face or throat.
• Corneal ulceration or persistent epithelial defect.
• Significant vision loss or sudden visual disturbances.
• Persistent eye pain unresponsive to treatment.
• Severe eyelid edema or cellulitis.
• Systemic hypersensitivity reactions such as rash or urticaria.

When using Ketotifen ophthalmic solution, consider the following precautions.

• Hypersensitivity: discontinue if signs of severe allergic reaction occur.
• Contact lenses: avoid wearing lenses during treatment and for at least 15 minutes after instillation.
• Ocular infection: stop use and seek medical advice if infection is suspected.
• Children: keep out of reach of children; use only under professional supervision.
• Contamination: do not use the solution if the bottle is damaged or the solution appears cloudy.
• Store at room temperature: keep in the original container, protect from light and moisture, and discard after the indicated period after opening.

Ketotifen may interact with other ocular or systemic agents.

Major Interactions (Avoid)

• Concurrent use with other ocular antihistamines may increase local irritation.
• Combination with preservative‑containing contact lens solutions can exacerbate toxicity.
• Use together with topical anesthetics may mask signs of corneal injury.

Moderate Interactions (Monitor Closely)

• Systemic antihistamines may enhance sedation when used together.
• Co‑administration with topical corticosteroids may mask infection signs.
• Use with ocular non‑steroidal anti‑inflammatory drugs (NSAIDs) may raise the risk of corneal complications.
• Interaction with systemic mast‑cell stabilizers may increase ocular dryness.
• Concomitant use with other eye‑drop medications may require spacing to avoid dilution effects.