Product image of Ketotifen Wzf (Ketotifen) supplied by GNH India

Ketotifen Wzf

Active Ingredient:
Ketotifen
Origin:
EU

Ketotifen Wzf (Ketotifen)

Ketotifen, the active ingredient in Ketotifen Wzf, is an antihistamine (H1 receptor antagonist) and mast cell stabilizer presented as an oral dosage form for oral use. It is employed to treat allergic rhinitis, allergic conjunctivitis, and to provide prophylaxis of asthma in both children and adults.

GNH India supplies Ketotifen Wzf as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides regulatory‑approved batches to meet global demand with reliable logistics and documentation support.

Manufacturer / TM Owner

Zaklady Farmaceutyczne Polpharma S.A.

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

  • Ketotifen is used in the allergy and asthma therapeutic area to control histamine‑mediated symptoms.
  • Allergic rhinitis: reduces nasal congestion, itching, sneezing and rhinorrhea.
  • Allergic conjunctivitis: alleviates eye itching, redness, tearing and swelling.
  • Asthma prophylaxis: helps prevent bronchospasm and airway inflammation by stabilizing mast cells.

How It Works

  • Ketotifen selectively blocks histamine H1 receptors on target cells, preventing histamine‑induced vascular permeability and sensory nerve activation. In parallel, it stabilizes mast cell membranes, inhibiting degranulation and the subsequent release of inflammatory mediators such as leukotrienes, prostaglandins and cytokines. This dual action reduces both immediate allergic responses and late‑phase inflammation, contributing to symptom control in allergic rhinitis, conjunctivitis and asthma.

Side Effects

Ketotifen may cause a range of adverse reactions, varying from mild to serious.

Common Side Effects

  • Drowsiness: feeling of sleepiness or reduced alertness.
  • Dry mouth: decreased salivation leading to thirst.
  • Headache: mild to moderate head pain.
  • Nausea: upset stomach or urge to vomit.
  • Dizziness: sensation of light‑headedness or unsteadiness.
  • Weight gain: increase in body weight over time.
  • Abdominal pain: discomfort in the stomach area.

Serious or Rare Side Effects

  • Stevens‑Johnson syndrome: severe skin reaction with blistering.
  • Anaphylaxis: life‑threatening allergic reaction with airway swelling.
  • Hepatic dysfunction: abnormal liver enzymes or jaundice.
  • Agranulocytosis: severe reduction in white blood cells.
  • Cardiac arrhythmia: irregular heart rhythm.

Precautions & Warnings

  • When prescribing ketotifen, several safety considerations should be observed to minimize risk.
  • Pregnancy: safety not established; avoid unless benefits outweigh risks.
  • Breastfeeding: unknown excretion; consider risk‑benefit before use.
  • Renal impairment: dose adjustment may be needed; monitor renal function.
  • Elderly patients: increased susceptibility to sedation and anticholinergic effects; start low.
  • Concomitant CNS depressants: may enhance drowsiness; use caution.
  • Store at below 25°C: keep in the original container, protect from moisture.

Avoid Interactions

Ketotifen can interact with other medicines, affecting its efficacy or safety.

Major Interactions (Avoid)

  • Potent CYP3A4 inhibitors: may increase ketotifen plasma concentrations.
  • Monoamine oxidase inhibitors (MAOIs): risk of additive central nervous system depression.
  • Other antihistamines: can cause excessive sedation.

Moderate Interactions (Monitor Closely)

  • Alcohol: may potentiate drowsiness.
  • CNS depressants (e.g., benzodiazepines): monitor for enhanced sedation.
  • Theophylline: ketotifen may reduce its bronchodilator effect.

Frequently Asked Questions

Ketotifen Wzf is prescribed to manage symptoms of allergic rhinitis and allergic conjunctivitis, and it is also used as a prophylactic agent to help prevent asthma attacks by stabilising mast cells and blocking histamine activity.

Ketotifen works by selectively antagonising histamine H1 receptors, which reduces the immediate allergic response, and by stabilising mast cell membranes, which limits the release of inflammatory mediators that contribute to late‑phase allergic reactions.

The dosage of ketotifen is determined by the prescribing clinician based on the patient’s age, condition severity and overall health. No fixed regimen is provided here; the prescriber will set the appropriate dose and schedule.

Safety data for ketotifen during pregnancy and lactation are limited. It is generally advised to avoid use unless the potential benefit justifies the potential risk to the fetus or infant, and decisions should be made in consultation with a healthcare professional.

To place an order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Ketotifen combines H1‑receptor antagonism with mast‑cell stabilisation, offering both immediate symptom relief and prevention of late‑phase inflammation. Many other antihistamines act only on H1 receptors, so ketotifen may provide broader control for patients with both allergic and asthmatic components.

Store the product at temperatures below 25 °C, in its original packaging, and protect it from moisture and direct sunlight. Keep the container tightly closed and out of reach of children.

Ketotifen Wzf is taken orally, usually with or without food, as directed by the prescribing clinician. The tablet should be swallowed whole with a glass of water and not crushed or chewed unless specifically instructed.

Serious adverse reactions can include severe skin conditions such as Stevens‑Johnson syndrome, life‑threatening anaphylaxis, hepatic dysfunction, agranulocytosis and cardiac arrhythmias. Patients should seek immediate medical attention if they notice any of these symptoms.

Ketotifen should be avoided in individuals with known hypersensitivity to the drug or any of its excipients, in patients with severe hepatic impairment, and in those for whom the risk of sedation or anticholinergic effects is unacceptable, unless a healthcare professional determines otherwise.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Related Products

Other formulations containing Ketotifen

A

A
A

A
A

A
A

A

Browse all products →

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Regulatory recognitions

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.

SGS GSDP Certification

GSDP Compliant from SGS

URS ISO 9001

URS ISO 9001 Certification

FDA Maharashtra

Licensed by FDA Maharashtra

IEC License DGFT

IEC License issued by DGFT