Product image of Ketotifeno Farmalider (Ketotifen Hydrogen Fumarate) supplied by GNH India

Ketotifeno Farmalider

Active Ingredient:
Ketotifen Hydrogen Fumarate
Origin:
EU

Ketotifeno Farmalider (Ketotifen Hydrogen Fumarate)

Ketotifen hydrogen fumarate, the active ingredient in Ketotifeno Farmalider, is an antihistamine and mast cell stabilizer presented as an ophthalmic solution for ocular use. It relieves symptoms of allergic conjunctivitis such as itching, redness and swelling in patients with seasonal or perennial eye allergies.

GNH India supplies Ketotifeno Farmalider as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Farmalider, S.A.

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Indications & Clinical Uses

  • Ketotifeno Farmalider is used to manage ocular allergic conditions by targeting histamine‑mediated inflammation.
  • Allergic conjunctivitis: reduces itching, redness and swelling of the eye.
  • Ocular itching due to allergy: provides rapid relief of itch sensation.
  • Redness from eye allergy: diminishes vascular congestion and visible redness.

How It Works

  • Ketotifen hydrogen fumarate blocks H1 histamine receptors on ocular tissues and stabilises mast cells, preventing degranulation and the subsequent release of inflammatory mediators such as histamine, leukotrienes and prostaglandins. This dual action reduces both immediate and late‑phase allergic responses in the conjunctiva, leading to symptom relief.

Side Effects

Ketotifeno Farmalider may cause local ocular reactions and, rarely, systemic effects.

Common Side Effects

  • Transient burning or stinging sensation after instillation.
  • Mild blurred vision lasting a few minutes.
  • Dry eye or foreign‑body feeling.
  • Mild headache.
  • Temporary increased tearing.

Serious or Rare Side Effects

  • Severe allergic reaction (e.g., angio‑edema of the eyelid).
  • Persistent eye irritation or corneal ulceration.
  • Vision loss.
  • Significant intra‑ocular pressure rise.
  • Systemic hypersensitivity (rash, urticaria).

Precautions & Warnings

  • Before using Ketotifeno Farmalider, consider the following precautions.
  • Avoid use in patients with known hypersensitivity to ketotifen or any excipients.
  • Do not apply to infected or inflamed eyes without medical advice.
  • Monitor for worsening ocular symptoms; discontinue if severe irritation occurs.
  • Use with caution in patients taking other ocular antihistamines or steroids.
  • Store at below 25°C: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Ketotifeno Farmalider may interact with other medications affecting ocular or systemic histamine pathways.

Major Interactions (Avoid)

  • Concurrent use of systemic antihistamines that cause additive sedation.
  • Co‑administration with ocular vasoconstrictors that may increase intra‑ocular pressure.

Moderate Interactions (Monitor Closely)

  • Use with other mast cell stabilisers may enhance local effects.
  • Systemic MAO inhibitors may potentiate antihistaminic activity.
  • Topical corticosteroids may mask signs of infection when used together.

Frequently Asked Questions

Ketotifeno Farmalider is an ophthalmic preparation containing ketotifen hydrogen fumarate. It is indicated for the relief of ocular allergy symptoms such as itching, redness and swelling associated with allergic conjunctivitis.

Ketotifen hydrogen fumarate blocks H1 histamine receptors on the conjunctival surface and stabilises mast cells, preventing the release of histamine and other inflammatory mediators. This dual action reduces both immediate and delayed allergic inflammation in the eye.

The dosing regimen for Ketotifeno Farmalider is determined by the prescribing clinician based on the severity of the allergic response and patient tolerance. Typically, one or two drops are instilled in the affected eye(s) as directed.

Safety data for ketotifen hydrogen fumarate in pregnancy and lactation are limited. The product should only be used if the potential benefit justifies any possible risk to the fetus or infant, and this decision should be made by a healthcare professional.

To place an order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Ketotifeno Farmalider combines H1‑receptor antagonism with mast‑cell stabilisation, offering both rapid symptom relief and longer‑term control. Some alternatives provide only antihistamine activity, which may require more frequent dosing for comparable effect.

Store the ophthalmic solution at temperatures below 25 °C, in its original packaging, protected from moisture and direct sunlight. Do not freeze the product.

The product is applied topically to the eye. After washing hands, instil the prescribed number of drops into the conjunctival sac of the affected eye(s) and close the eyelids gently. Avoid touching the dropper tip to any surface.

Serious risks include severe allergic reactions such as angio‑edema of the eyelid, corneal ulceration, significant intra‑ocular pressure elevation, and rare cases of vision loss. Immediate medical attention is required if any of these occur.

Individuals with known hypersensitivity to ketotifen, its salts, or any formulation excipients should avoid using the product. It is also contraindicated in eyes that are actively infected or inflamed without physician supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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