Product image of Kevesy (Levetiracetam) supplied by GNH India

Kevesy

Active Ingredient:
Levetiracetam
Origin:
EU

Kevesy (Levetiracetam)

Levetiracetam, the active ingredient in Kevesy, is an antiepileptic presented as an intravenous solution for intravenous use. It is used to treat partial‑onset, generalized and myoclonic seizures in patients with epilepsy.

GNH India supplies Kevesy as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals worldwide.

Manufacturer / TM Owner

Stragen Uk Ltd.

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Indications & Clinical Uses

Levetiracetam is an antiepileptic medication used to control various seizure types.

  • Partial‑onset seizures: reduces frequency and severity of focal seizures.
  • Generalized seizures: helps prevent tonic‑clonic episodes.
  • Myoclonic seizures: decreases sudden muscle jerks associated with epilepsy.

How It Works

  • Levetiracetam binds to the synaptic vesicle protein SV2A, modulating neurotransmitter release and stabilizing neuronal membranes. This action reduces neuronal excitability and suppresses the abnormal electrical activity that leads to seizures, providing broad-spectrum anticonvulsant effects without significant interaction with traditional ion channels.

Side Effects

Levetiracetam may cause a range of adverse reactions, from mild to serious.

Common Side Effects

  • Dizziness: transient sensation of light‑headedness.
  • Fatigue: feeling unusually tired or weak.
  • Headache: mild to moderate pain in the head region.
  • Somnolence: increased sleepiness during the day.
  • Nausea: upset stomach or urge to vomit.
  • Irritability: mood changes or increased agitation.

Serious or Rare Side Effects

  • Severe allergic reaction: rash, swelling, or difficulty breathing.
  • Stevens‑Johnson syndrome: rare but serious skin disorder.
  • Blood dyscrasias: abnormal blood cell counts.
  • Suicidal thoughts: emergence of depressive or suicidal ideation.
  • Severe skin rash: extensive blistering or peeling.
  • Respiratory depression: markedly reduced breathing effort.

Precautions & Warnings

Before initiating therapy with Kevesy, consider the following safety measures.

  • Renal impairment: adjust dose in patients with reduced kidney function.
  • Hepatic impairment: monitor liver function and consider dose modification.
  • Pregnancy: use only if the potential benefit justifies the potential risk to the fetus.
  • Concomitant CNS depressants: observe for enhanced sedation or respiratory effects.
  • Mood changes: monitor for depression or suicidal ideation.
  • Store at ambient temperature: keep in the original container, protect from light and moisture.

Avoid Interactions

Levetiracetam has a low interaction profile, but certain drugs may alter its effectiveness or increase risk.

Major Interactions (Avoid)

  • Carbamazepine: enzyme induction may lower levetiracetam levels.
  • Phenytoin: may reduce levetiracetam plasma concentration.
  • Phenobarbital: can decrease levetiracetam exposure.
  • Rifampin: strong inducer that may diminish therapeutic effect.
  • Topiramate: may increase risk of CNS side effects.

Moderate Interactions (Monitor Closely)

  • Benzodiazepines: additive sedation and respiratory depression.
  • Alcohol: enhanced central nervous system depression.
  • Other antiepileptics: monitor seizure control and side‑effect profile.
  • Antidepressants: watch for mood alterations.
  • Antipsychotics: potential increase in dizziness or somnolence.

Frequently Asked Questions

Kevesy is an intravenous formulation of levetiracetam used to treat partial‑onset, generalized, and myoclonic seizures in patients with epilepsy. It provides rapid plasma concentrations suitable for acute seizure management in hospital settings.

Levetiracetam binds to the synaptic vesicle protein SV2A, which modulates neurotransmitter release. This reduces neuronal excitability and helps prevent the abnormal electrical discharges that cause seizures.

The appropriate dose of Kevesy is determined by the prescribing clinician based on the patient’s age, weight, renal function, and seizure type. Dosage regimens are individualized and should follow the prescriber’s instructions.

The safety of levetiracetam in pregnancy and lactation is not fully established. It should only be used if the potential benefit outweighs the potential risk to the fetus or infant, and the decision should be made by a qualified healthcare professional.

To order Kevesy, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if needed), and import documentation.

Kevesy (levetiracetam) offers a broad spectrum of seizure control with a relatively low potential for drug‑drug interactions compared with many enzyme‑inducing antiepileptics such as carbamazepine or phenytoin. Its intravenous formulation allows rapid achievement of therapeutic levels, which can be advantageous in acute care.

Kevesy should be stored at ambient temperature, protected from light and moisture, and kept in its original packaging until use. Do not freeze the solution and avoid exposing it to extreme temperatures.

Kevesy is administered intravenously by a healthcare professional. The solution is typically infused over a prescribed period, often as a loading dose followed by maintenance infusions, according to the clinician’s dosing schedule.

Serious risks include severe allergic reactions, Stevens‑Johnson syndrome, blood dyscrasias, and emergence of suicidal thoughts or depression. Patients should be monitored for any signs of rash, mood changes, or respiratory distress, and medical attention should be sought immediately if these occur.

Kevesy is contraindicated in patients with known hypersensitivity to levetiracetam or any of the formulation components. Caution is also advised for individuals with severe renal impairment unless dose adjustments are made, and it should be avoided in patients where the risk of serious skin reactions is high.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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