Product image of Kidofen (Ibuprofen) supplied by GNH India

Kidofen

Active Ingredient:
Ibuprofen
Origin:
EU

Kidofen (Ibuprofen)

Ibuprofen, the active ingredient in Kidofen, is a nonsteroidal anti-inflammatory drug (NSAID) presented as an oral dosage form for oral use. It is used to relieve pain, reduce fever, and diminish inflammation in conditions such as arthritis and other musculoskeletal disorders.
GNH India supplies Kidofen as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Aflofarm Farmacja Polska Sp. Z O.O.

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Indications & Clinical Uses

Ibuprofen acts systemically to alleviate symptoms associated with inflammatory and painful conditions.

  • Pain: Provides relief of mild to moderate acute pain such as headache, dental pain, or postoperative discomfort.
  • Fever: Lowers elevated body temperature in febrile states caused by infection or inflammation.
  • Inflammation: Reduces swelling and redness in soft‑tissue injuries and inflammatory joint diseases.
  • Arthritic conditions: Improves joint mobility and lessens discomfort in osteoarthritis and rheumatoid arthritis.

How It Works

  • Ibuprofen reversibly inhibits cyclooxygenase‑1 (COX‑1) and cyclooxygenase‑2 (COX‑2) enzymes, decreasing the conversion of arachidonic acid to prostaglandins. The reduced prostaglandin synthesis diminishes peripheral sensitization of nociceptors, lowers the hypothalamic set‑point for temperature, and limits inflammatory exudate formation, resulting in analgesic, antipyretic, and anti‑inflammatory effects.

Side Effects

Adverse reactions may vary in frequency and severity.

Common Side Effects

  • Gastrointestinal discomfort: nausea, dyspepsia, or mild abdominal pain.
  • Headache: transient mild to moderate headache.
  • Dizziness: occasional light‑headedness or vertigo.
  • Rash: mild skin erythema or pruritus.

Serious or Rare Side Effects

  • Gastrointestinal ulceration or bleeding: severe abdominal pain or melena.
  • Renal impairment: reduced urine output or elevated creatinine.
  • Hepatotoxicity: jaundice or abnormal liver enzymes.
  • Anaphylaxis: sudden swelling, difficulty breathing, or hypotension.

Precautions & Warnings

Before using Ibuprofen, consider the following safety measures.

  • Cardiovascular risk: avoid prolonged high‑dose use in patients with heart disease.
  • Gastrointestinal history: use with caution in individuals with ulcer disease or bleeding disorders.
  • Renal function: monitor kidney function in patients with chronic kidney disease.
  • Concomitant medications: review all current drugs for potential interactions.
  • Pregnancy and lactation: consult a healthcare professional before use.

Store at ambient temperature: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Ibuprofen can affect the efficacy or safety of several other medicines.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased risk of serious bleeding.
  • Other NSAIDs or aspirin: heightened gastrointestinal toxicity.
  • Selective serotonin reuptake inhibitors (SSRIs): elevated bleeding risk.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: possible reduction in antihypertensive effect and renal function.
  • Diuretics: may diminish diuretic response and affect kidney function.
  • Lithium: increased lithium levels, requiring serum monitoring.

Frequently Asked Questions

Kidofen contains ibuprofen, which is commonly used to treat mild to moderate pain, reduce fever, and lessen inflammation. It is effective for headaches, dental pain, musculoskeletal injuries, and inflammatory joint disorders such as osteoarthritis and rheumatoid arthritis.

Ibuprofen works by reversibly blocking the cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, which are essential for producing prostaglandins. By lowering prostaglandin levels, it reduces pain signaling, lowers fever, and diminishes inflammation at the site of injury or disease.

The appropriate dose of Kidofen is determined by the prescribing healthcare professional based on the patient’s age, weight, condition being treated, and overall health status. Patients should follow the prescriber’s instructions and never exceed the recommended amount.

Safety of ibuprofen during pregnancy and lactation depends on the trimester and individual risk factors. It is generally avoided in the third trimester and used only if clearly needed in earlier stages. Breastfeeding mothers should consult a healthcare provider before use.

To place an order, submit an enquiry on the Kidofen product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Kidofen (ibuprofen) offers a balanced profile of analgesic, antipyretic and anti‑inflammatory activity with a relatively short half‑life, allowing flexible dosing. Compared with longer‑acting NSAIDs such as naproxen, ibuprofen may have a lower risk of prolonged gastrointestinal exposure but similar efficacy for acute pain.

Kidofen should be stored at ambient temperature, preferably below 25 °C. Keep the product in its original packaging, protect it from moisture, heat and direct sunlight, and ensure the container is tightly closed to maintain stability.

Kidofen is taken orally, usually with a full glass of water. It can be taken with or without food, although taking it with food may reduce mild stomach upset. The exact administration schedule should follow the prescriber’s directions.

Serious risks include gastrointestinal bleeding or ulceration, severe allergic reactions such as anaphylaxis, kidney injury, and increased cardiovascular events especially with high‑dose or long‑term use. Patients should seek immediate medical attention if they notice signs of bleeding, severe rash, or sudden swelling.

Kidofen should be avoided by individuals with known hypersensitivity to ibuprofen or other NSAIDs, those with active gastrointestinal bleeding, severe heart failure, or advanced renal impairment. It is also contraindicated in the third trimester of pregnancy and should be used with caution in patients on anticoagulants.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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