Product image of Kidofen (Ibuprofen) supplied by GNH India

Kidofen

Active Ingredient:
Ibuprofen
Origin:
EU

Kidofen (Ibuprofen)

Ibuprofen, the active ingredient in Kidofen, is a nonsteroidal anti-inflammatory drug (NSAID) presented as a suppository for rectal use. It treats pain, fever, inflammation and dysmenorrhea in children and adults as appropriate.

GNH India supplies Kidofen as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Aflofarm Farmacja Polska Sp. Z O.O.

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Indications & Clinical Uses

Ibuprofen, an NSAID, reduces inflammation and pain by inhibiting cyclooxygenase enzymes.

  • Pain: provides relief of mild to moderate pain.
  • Fever: lowers elevated body temperature.
  • Inflammation: diminishes swelling and inflammatory discomfort.
  • Dysmenorrhea: eases menstrual cramps and associated pain.

How It Works

  • Ibuprofen non‑selectively inhibits cyclooxygenase‑1 (COX‑1) and cyclooxygenase‑2 (COX‑2) enzymes, decreasing the conversion of arachidonic acid to prostaglandins. The reduced prostaglandin synthesis leads to lowered inflammation, analgesia, and antipyresis at sites of tissue injury or infection.

Side Effects

Kidofen may cause a range of adverse reactions. Most are mild and reversible.

Common Side Effects

  • Abdominal discomfort.
  • Nausea or mild vomiting.
  • Headache.
  • Local rectal irritation.

Serious or Rare Side Effects

  • Gastrointestinal bleeding or ulceration.
  • Severe allergic reaction (anaphylaxis).
  • Kidney function impairment.

Precautions & Warnings

Before using Kidofen, consider the following precautions.

  • Allergy assessment: avoid if known hypersensitivity to ibuprofen or other NSAIDs.
  • Dose minimisation: use the lowest effective amount for the shortest duration.
  • Ulcer risk: do not use in patients with active peptic ulcer disease.
  • Renal monitoring: exercise caution in dehydration or existing kidney impairment.
  • Anticoagulant caution: assess bleeding risk when combined with anticoagulants.
  • Store at room temperature: keep in the original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Kidofen can interact with several medicines; monitoring is advised.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin) – increased bleeding risk.
  • Other NSAIDs or aspirin – additive gastrointestinal toxicity.
  • Corticosteroids – heightened risk of ulceration.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs – possible decline in renal function.
  • SSRIs – may increase bleeding tendency.

Frequently Asked Questions

Kidofen is an ibuprofen‑based rectal suppository indicated for the temporary relief of mild to moderate pain, reduction of fever, and mitigation of inflammation, including menstrual (dysmenorrhea) discomfort. It is an over‑the‑counter NSAID commonly employed when oral administration is not feasible or preferred.

Ibuprofen exerts its effect by non‑selectively inhibiting the cyclooxygenase‑1 and cyclooxygenase‑2 enzymes. This inhibition blocks the synthesis of prostaglandins, which are mediators of inflammation, pain, and fever, thereby providing analgesic, antipyretic, and anti‑inflammatory actions.

The appropriate dose of Kidofen is determined by a qualified healthcare professional based on the patient’s age, weight, clinical condition, and response to therapy. Patients should follow the prescriber’s instructions and the product labeling without exceeding the recommended amount.

The safety of ibuprofen suppositories during pregnancy and lactation has not been definitively established. Women who are pregnant, planning to become pregnant, or breastfeeding should consult their physician before using Kidofen to weigh potential risks and benefits.

To place an order, submit an enquiry on the Kidofen product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.

Kidofen delivers ibuprofen, a widely used NSAID with a well‑characterised safety profile. Compared with naproxen, ibuprofen has a shorter half‑life, allowing more flexible dosing, while offering similar analgesic and anti‑inflammatory efficacy. Unlike acetaminophen, ibuprofen also provides anti‑inflammatory action but carries a higher risk of gastrointestinal irritation.

Kidofen suppositories should be stored at room temperature, below 25 °C, in their original blister pack to protect them from moisture and direct sunlight. Keep the product out of reach of children and avoid storing in bathrooms or other humid environments.

Kidofen is inserted rectally. The user should wash hands, remove the suppository from its packaging, and gently insert it into the rectum, preferably after a bowel movement. The suppository melts at body temperature, delivering ibuprofen systemically.

Serious adverse events, although uncommon, include gastrointestinal bleeding or ulceration, severe allergic reactions such as anaphylaxis, and impaired kidney function. Patients should seek immediate medical attention if they experience black stools, vomiting blood, rash, swelling of the face or throat, or sudden decrease in urine output.

Kidofen should be avoided by individuals with known hypersensitivity to ibuprofen or any NSAID, those with active peptic ulcer disease, severe heart failure, uncontrolled hypertension, or significant renal or hepatic impairment unless directed by a physician. It is also contraindicated in patients taking anticoagulants without medical supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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