Kidtrayze (Zinc Chloride, Potassium Iodide, Sodium Selenite, Copper Chloride Dihydrate, Manganese Chloride Tetr)

Kidtrayze is used to address trace element deficiencies in patients receiving parenteral nutrition or at risk of micronutrient loss.

• Parenteral nutrition support: supplies essential zinc, iodine, selenium, copper, and manganese to patients on total parenteral nutrition.
• Prevention of micronutrient deficiency: helps maintain adequate trace element levels in critically ill or postoperative patients.
• Management of malabsorption: provides necessary trace elements for individuals with gastrointestinal disorders that impair absorption.
• Support for immune function: contributes to antioxidant capacity and immune response in patients with prolonged hospitalization.

• Kidtrayze delivers a combination of essential trace elements directly into the bloodstream, bypassing gastrointestinal absorption. Zinc, copper, manganese, iodine, and selenium act as cofactors for numerous enzymes involved in oxidative metabolism, DNA synthesis, thyroid hormone production, and antioxidant defenses. By supplying these micronutrients intravenously, the product ensures immediate bioavailability, supporting cellular functions and metabolic pathways that depend on trace element cofactors.

Kidtrayze may be associated with infusion‑related reactions and laboratory abnormalities.

Common Side Effects

• Injection site pain: mild discomfort at the catheter site.
• Transient fever: temporary rise in body temperature.
• Electrolyte imbalance: mild changes in serum zinc or copper levels.
• Nausea: occasional feeling of nausea during infusion.

Serious or Rare Side Effects

• Anaphylactic reaction: severe allergic response requiring immediate medical intervention.
• Hepatotoxicity: rare liver enzyme elevation.
• Renal impairment: potential worsening of kidney function in susceptible patients.
• Methemoglobinemia: rare reduction in oxygen‑carrying capacity due to iodine excess.

When using Kidtrayze, clinicians should consider several safety measures to minimize risks.

• Patient assessment: evaluate baseline trace element status and organ function before initiation.
• Dose adjustment: modify infusion rate in patients with hepatic or renal impairment.
• Monitoring: check serum zinc, copper, selenium, and iodine levels regularly during therapy.
• Compatibility: verify compatibility with other intravenous solutions to avoid precipitation.
• Allergic history: avoid use in individuals with known hypersensitivity to any component.
• Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Kidtrayze can interact with certain medications and nutrients, affecting efficacy or safety.

Major Interactions (Avoid)

• Chelating agents: deferoxamine or EDTA may bind trace elements, reducing their availability.
• High-dose vitamin C: can increase copper excretion and alter copper levels.
• Thyroid hormone therapy: excess iodine may interfere with levothyroxine dosing.

Moderate Interactions (Monitor Closely)

• Antacids containing aluminum or magnesium: may affect absorption of trace elements if given concurrently.
• Diuretics: loop diuretics can increase urinary loss of zinc and copper.
• Anticoagulants: trace elements may influence coagulation parameters; monitor INR or aPTT as needed.