Product image of Kilatim (Timolol Maleate, Latanoprost) supplied by GNH India

Kilatim

Active Ingredient:
Timolol Maleate, Latanoprost
Origin:
EU

Kilatim (Timolol Maleate, Latanoprost)

Timolol maleate and Latanoprost, the active ingredients in Kilatim, are a beta‑blocker and a prostaglandin analog presented as an ophthalmic solution for ocular use. They treat primary open‑angle glaucoma and ocular hypertension in adults.
GNH India supplies Kilatim as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Laboratoire Chauvin

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Indications & Clinical Uses

  • Kilatim, a combination beta‑blocker and prostaglandin analog, is used to manage intra‑ocular pressure in glaucoma and ocular hypertension.
  • Primary open‑angle glaucoma: reduces intra‑ocular pressure to slow disease progression.
  • Ocular hypertension: lowers eye pressure to prevent conversion to glaucoma.
  • Normal‑tension glaucoma: helps control pressure when optic nerve damage is present despite normal pressure readings.

How It Works

  • Timolol maleate blocks non‑selective β‑adrenergic receptors in the ciliary body, decreasing aqueous humor production. Latanoprost, a prostaglandin F2α analog, binds prostanoid FP receptors, enhancing uveoscleral outflow of aqueous humor. The combined actions lower intra‑ocular pressure more effectively than either component alone.

Side Effects

Common Side Effects

  • Eye irritation or burning sensation.
  • Blurred vision shortly after instillation.
  • Redness of the conjunctiva.
  • Dry eye or foreign‑body feeling.

Serious or Rare Side Effects

  • Severe allergic reaction with swelling of the eyelid.
  • Ocular inflammation or uveitis.
  • Sudden loss of vision.
  • Systemic bradycardia or bronchospasm, especially in susceptible patients.

Precautions & Warnings

Before using Kilatim, consider the following precautions:

  • Assess cardiovascular status: avoid in patients with severe bradycardia or heart block.
  • Monitor respiratory condition: use with caution in asthma or COPD.
  • Check for sulfonamide allergy: latanoprost may trigger hypersensitivity.
  • Avoid concurrent ocular beta‑blockers: risk of additive hypotensive effect.
  • Store at room temperature: keep in the original container, protect from light and moisture.

Avoid Interactions

Kilatim may interact with other medicines as follows:

Major Interactions (Avoid)

  • Systemic non‑selective beta‑blockers: additive bradycardia.
  • Beta‑agonist inhalers (e.g., albuterol): reduced timolol efficacy.
  • Other prostaglandin analog eye drops: increased ocular inflammation.
  • MAO inhibitors: potential systemic interaction with timolol.

Moderate Interactions (Monitor Closely)

  • Systemic carbonic anhydrase inhibitors: may affect intra‑ocular pressure control.
  • Topical corticosteroids: may diminish latanoprost effect.

Frequently Asked Questions

Kilatim is a prescription ophthalmic solution that combines timolol maleate and latanoprost to lower intra‑ocular pressure. It is indicated for adults with primary open‑angle glaucoma or ocular hypertension, helping to prevent optic nerve damage and preserve vision.

Timolol maleate is a non‑selective beta‑adrenergic blocker. By inhibiting β‑receptors in the ciliary body, it reduces the production of aqueous humor, which lowers the pressure inside the eye.

The dosing regimen for Kilatim is determined by the prescribing ophthalmologist. Typically, one drop is instilled into the affected eye(s) once daily, but the exact frequency and duration are individualized based on patient response.

Safety of Kilatim in pregnancy or lactation has not been fully established. Healthcare providers should weigh potential benefits against risks and consider alternative treatments if appropriate.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and necessary import documentation.

Kilatim combines a beta‑blocker and a prostaglandin analog, offering dual mechanisms—reduced aqueous humor production and increased outflow. This can provide greater pressure reduction than single‑agent drops, though individual response varies and tolerability must be considered.

Kilatim should be stored at room temperature, below 25 °C. Keep the bottle in its original packaging, protect it from direct sunlight and moisture, and discard any solution that appears discolored or contains particles.

Kilatim is applied as an eye drop. The patient should wash hands, tilt the head back, pull down the lower eyelid to create a pocket, and place one drop into the conjunctival sac. Close the eye gently and avoid blinking excessively for a few seconds.

Serious risks include severe allergic reactions, ocular inflammation, sudden vision loss, systemic bradycardia, and bronchospasm. Patients should seek immediate medical attention if they experience swelling, severe eye pain, rapid vision changes, or breathing difficulties.

Kilatim is contraindicated in patients with known hypersensitivity to timolol, latanoprost, or any component of the formulation, as well as those with severe sinus node dysfunction, uncontrolled asthma, or active ocular infections.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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