Product image of Kilspax (Phloroglucinol Dihydrate) supplied by GNH India

Kilspax

Active Ingredient:
Phloroglucinol Dihydrate
Origin:
EU

Kilspax (Phloroglucinol Dihydrate)

Phloroglucinol, the active ingredient in Kilspax, is an antispasmodic presented as an oral dosage form for oral use. It helps relieve smooth‑muscle spasms that cause abdominal pain, biliary colic, renal colic and menstrual cramps in adult patients, and is indicated for use in both acute and recurrent episodes.

GNH India supplies Kilspax as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, providing reliable sourcing, regulatory support and global logistics for consistent product availability and ensures compliance with EU pharmacopeial standards.

Manufacturer / TM Owner

Velit Biopharma S.R.L

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

  • Kilspax (phloroglucinol) acts as a smooth‑muscle relaxant to alleviate spasm‑related conditions.
  • Abdominal pain: reduces painful intestinal spasms, improving comfort.
  • Biliary colic: relaxes biliary smooth muscle, facilitating bile flow and relieving colicky pain.
  • Renal colic: eases ureteral smooth‑muscle spasm, helping to diminish flank pain.
  • Menstrual cramps: diminishes uterine muscle contractions, decreasing dysmenorrhea severity.

How It Works

  • Phloroglucinol exerts its antispasmodic effect by directly inhibiting calcium influx into smooth‑muscle cells, which decreases intracellular calcium concentration and prevents contraction. By stabilising the muscle membrane, it relaxes smooth muscle in the gastrointestinal, biliary, urinary and uterine tracts, thereby reducing spasm‑induced pain. The reduction of calcium‑dependent phosphorylation of myosin light chains leads to decreased contractile force, and the overall effect is a rapid onset of smooth‑muscle relaxation without significant anticholinergic activity.

Side Effects

Phloroglucinol may be associated with several adverse reactions, most of which are mild and reversible.

Common Side Effects

  • Nausea
  • Dizziness
  • Headache
  • Dry mouth
  • Abdominal discomfort
  • Diarrhoea

Serious or Rare Side Effects

  • Allergic reactions (rash, urticaria)
  • Severe hypotension
  • Hepatic enzyme elevation
  • Anaphylaxis
  • Severe neutropenia

Precautions & Warnings

  • Before prescribing Kilspax, clinicians should consider the following precautions.
  • Assess renal function: adjust use in severe renal impairment.
  • Avoid in known hypersensitivity to phloroglucinol.
  • Use caution in patients with hepatic disease.
  • Monitor for signs of allergic reaction during initial therapy.
  • Store below 25°C: keep in the original pack, protect from moisture.

Avoid Interactions

Potential drug interactions should be reviewed prior to initiating therapy.

Major Interactions (Avoid)

  • Concurrent use with other antispasmodics: additive muscle relaxation may cause severe hypotension.
  • Combination with potent CYP inhibitors: may increase plasma levels of phloroglucinol.

Moderate Interactions (Monitor Closely)

  • Co‑administration with antihypertensives: may enhance blood‑pressure‑lowering effect.
  • Use with diuretics: monitor electrolyte balance.
  • Concurrent use with drugs that prolong QT interval: monitor cardiac rhythm.

Frequently Asked Questions

Kilspax contains phloroglucinol and is used to relieve smooth‑muscle spasms that cause abdominal pain, biliary colic, renal colic and menstrual cramps. It is prescribed for adults experiencing acute or recurrent episodes of these spasm‑related conditions.

Phloroglucinol works by blocking calcium entry into smooth‑muscle cells, which lowers intracellular calcium levels and prevents muscle contraction. This direct action relaxes the smooth muscle of the gastrointestinal, biliary, urinary and uterine tracts, reducing spasm‑induced discomfort.

The dosage of Kilspax is determined by the prescribing healthcare professional based on the patient’s condition, severity of symptoms and individual response. Patients should follow the exact regimen provided by their prescriber and not adjust the dose on their own.

Safety data for phloroglucinol in pregnancy and lactation are limited. It should only be used when the potential benefit to the mother outweighs any possible risk to the fetus or infant, and only under medical supervision.

To request Kilspax, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Kilspax (phloroglucinol) is a direct smooth‑muscle relaxant that does not possess anticholinergic activity, unlike agents such as hyoscine butylbromide. This can result in fewer anticholinergic side effects such as dry mouth or blurred vision, while providing comparable relief of spasm‑related pain.

Kilspax should be stored below 25 °C, in its original packaging, protected from moisture and direct sunlight. Keep the product out of reach of children and avoid exposing it to excessive heat or humidity to maintain its stability.

Kilspax is taken orally, usually with a glass of water. It can be taken with or without food, unless the prescriber advises otherwise. Swallow the tablet whole; do not crush or chew unless instructed by a healthcare professional.

The most serious risks include severe allergic reactions such as rash, urticaria or anaphylaxis, and marked hypotension that may lead to dizziness or fainting. Patients should seek immediate medical attention if they experience any signs of a severe reaction.

Kilspax should be avoided in individuals with known hypersensitivity to phloroglucinol or any of its excipients, and in patients with severe renal or hepatic impairment unless specifically directed by a physician. Caution is also advised for those taking multiple antispasmodic agents.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.