Product image of Kinderparacetamol Sam (Paracetamol) supplied by GNH India

Kinderparacetamol Sam

Active Ingredient:
Paracetamol
Origin:
EU

Kinderparacetamol Sam (Paracetamol)

Paracetamol, the active ingredient in Kinderparacetamol Sam, is an analgesic presented as a rectal formulation for pediatric use. It treats mild to moderate pain and fever in children.
GNH India supplies Kinderparacetamol Sam as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Nederlandse Service Apotheek Beheer B.V.

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Indications & Clinical Uses

  • Paracetamol acts as an analgesic and antipyretic, reducing pain and fever in the pediatric population.
  • Pain: provides relief from mild to moderate pain in children.
  • Fever: lowers elevated body temperature associated with common infections.
  • Headache: alleviates headache symptoms in pediatric patients.

How It Works

  • Paracetamol exerts its effect by inhibiting the enzyme cyclooxygenase (COX) in the central nervous system, which reduces the synthesis of prostaglandins involved in pain signaling and thermoregulation. This central action leads to analgesia and antipyresis without significant peripheral anti‑inflammatory activity.

Side Effects

Paracetamol is generally well tolerated, but adverse reactions can occur.

Common Side Effects

  • Nausea
  • Abdominal discomfort
  • Rash or mild skin irritation
  • Dizziness
  • Vomiting
  • Mild headache

Serious or Rare Side Effects

  • Severe skin reactions such as Stevens‑Johnson syndrome
  • Hepatotoxicity, especially with overdose or pre‑existing liver disease
  • Anaphylactic or severe allergic reactions
  • Blood disorders like thrombocytopenia
  • Acute renal impairment in susceptible individuals

Precautions & Warnings

  • Paracetamol should be used with attention to patient‑specific factors and proper handling.
  • Dosage: follow the prescriber's instructions and do not exceed the recommended amount.
  • Age: not for children under two months unless specifically directed by a clinician.
  • Liver disease: use with caution and monitor hepatic function.
  • Alcohol: avoid concurrent consumption to reduce liver risk.
  • Other medications: review for potential interactions before use.
  • Store at room temperature: keep in the original packaging, protect from moisture and heat.

Avoid Interactions

Paracetamol may interact with several medicines; awareness helps prevent adverse outcomes.

Major Interactions (Avoid)

  • Warfarin: increased risk of bleeding.
  • Isoniazid: heightened hepatotoxic potential.
  • Alcohol: amplified liver toxicity.

Moderate Interactions (Monitor Closely)

  • Carbamazepine: may reduce paracetamol efficacy.
  • Phenobarbital: may increase paracetamol metabolism, lowering its effect.

Frequently Asked Questions

Kinderparacetamol Sam is a rectal formulation of paracetamol indicated for the relief of mild to moderate pain and the reduction of fever in pediatric patients. It is commonly employed when oral administration is not feasible or preferred.

Paracetamol works by inhibiting cyclooxygenase enzymes in the central nervous system, which decreases the production of prostaglandins that mediate pain and regulate body temperature. This central inhibition provides analgesic and antipyretic effects without strong peripheral anti‑inflammatory activity.

The appropriate dose is determined by the prescribing healthcare professional based on the child’s age, weight, and clinical condition. No fixed regimen is provided here; the prescriber will specify the exact amount and frequency.

Safety data for rectal paracetamol in pregnancy and lactation are limited. It should only be used if clearly needed and after consultation with a qualified healthcare provider, who will weigh potential benefits against any possible risks.

To place an order, submit an enquiry on the product page at gnhindia.com, indicating the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, and will request trade or institutional credentials before providing pricing, availability, shipping details and any necessary import documentation.

Both paracetamol and ibuprofen relieve pain and fever, but ibuprofen also has anti‑inflammatory properties. Paracetamol is generally gentler on the stomach and preferred when anti‑inflammatory action is not required, whereas ibuprofen may be chosen for conditions involving inflammation.

Store the product at room temperature, below 25 °C, in its original packaging. Keep it away from moisture, direct sunlight and excessive heat to maintain stability and potency.

The medication is given rectally. The appropriate dose, as prescribed, is inserted into the rectum using the supplied applicator or a clean, dry finger, ensuring the child remains in a comfortable position for proper absorption.

Serious risks include severe liver injury, especially with overdose or in patients with pre‑existing liver disease, and rare but life‑threatening skin reactions such as Stevens‑Johnson syndrome. Prompt medical attention is required if signs of these conditions appear.

Children with known hypersensitivity to paracetamol or any excipients in the formulation should avoid it. It is also contraindicated in patients with severe hepatic impairment or those taking other medications that markedly increase the risk of liver toxicity.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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