Product image of Kinderparacetamol Zetpil Livsane (Paracetamol) supplied by GNH India

Kinderparacetamol Zetpil Livsane

Active Ingredient:
Paracetamol
Origin:
EU

Kinderparacetamol Zetpil Livsane (Paracetamol)

Paracetamol, the active ingredient in Kinderparacetamol Zetpil Livsane, is an analgesic presented as a rectal suppository for rectal use. It treats pain and fever in children.

GNH India supplies Kinderparacetamol Zetpil Livsane as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Healthypharm B.V.

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Indications & Clinical Uses

Paracetamol acts as an analgesic and antipyretic, reducing pain and fever through inhibition of prostaglandin synthesis.

  • Fever: lowers elevated body temperature in children.
  • Mild to moderate pain: alleviates discomfort from common ailments.
  • Post‑vaccination discomfort: provides relief after immunisation.

How It Works

  • Paracetamol inhibits cyclooxygenase (COX) enzymes, primarily COX‑2, in the central nervous system, leading to reduced synthesis of prostaglandins that mediate pain and fever. This central action provides antipyretic and analgesic effects without significant peripheral anti‑inflammatory activity.

Side Effects

Paracetamol may cause a range of adverse reactions, most of which are mild and reversible.

Common Side Effects

  • Mild rectal irritation or discomfort.
  • Nausea.
  • Abdominal discomfort.
  • Dizziness.

Serious or Rare Side Effects

  • Severe skin reactions such as Stevens‑Johnson syndrome.
  • Hepatic injury, especially with overdose.
  • Allergic reactions including anaphylaxis.

Precautions & Warnings

When using Kinderparacetamol Zetpil Livsane, consider the following safety measures.

  • Age restriction: not for infants under 2 months.
  • Liver function: avoid in severe hepatic impairment.
  • Concurrent use: limit total daily paracetamol from all sources.
  • Allergy: discontinue if rash or hypersensitivity develops.
  • Pregnancy and breastfeeding: consult a healthcare professional before use.
  • Store at room temperature: keep in original packaging, protect from moisture.

Avoid Interactions

Paracetamol can interact with several medicines; awareness helps prevent adverse outcomes.

Major Interactions (Avoid)

  • Alcohol: increased risk of liver toxicity.
  • Other paracetamol‑containing products: risk of overdose.
  • Warfarin: may enhance anticoagulant effect.

Moderate Interactions (Monitor Closely)

  • Carbamazepine: may reduce paracetamol plasma levels.
  • Isoniazid: may increase risk of hepatic injury.
  • Phenobarbital: may increase paracetamol metabolism.

Frequently Asked Questions

Kinderparacetamol Zetpil Livsane is a rectal suppository containing paracetamol, used to relieve mild to moderate pain and to reduce fever in children. It provides a convenient route when oral administration is not feasible.

Paracetamol works by inhibiting cyclooxygenase enzymes in the central nervous system, which reduces the production of prostaglandins. Lower prostaglandin levels diminish the perception of pain and help reset the body’s temperature set‑point, thereby lowering fever.

The appropriate dose is determined by the prescribing healthcare professional based on the child’s age, weight, and clinical condition. The prescriber will select the correct number and frequency of suppositories to achieve safe and effective therapy.

The safety of paracetamol suppositories in pregnancy and lactation has not been fully established. Women who are pregnant or breastfeeding should discuss use with their healthcare provider, who can weigh potential benefits against any unknown risks.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Compared with oral paracetamol formulations, the rectal suppository offers an alternative when swallowing is difficult or when rapid absorption is desired. Unlike ibuprofen, paracetamol has minimal anti‑inflammatory activity, which may be advantageous for children with gastric sensitivity.

Store the suppositories at room temperature, below 25 °C, in the original packaging. Protect them from moisture and direct sunlight to maintain stability and ensure the dosage form remains intact until use.

The suppository is inserted rectally, preferably after a bowel movement, using a gloved finger or an applicator if provided. The child should remain lying down for a few minutes to allow the suppository to melt and be absorbed.

Serious risks include severe skin reactions such as Stevens‑Johnson syndrome, hepatic injury especially with overdose, and rare allergic reactions like anaphylaxis. Prompt medical attention is required if any of these symptoms appear.

Children with known hypersensitivity to paracetamol or any component of the suppository should avoid it. It is also contraindicated in infants younger than two months and in patients with severe liver disease unless specifically directed by a physician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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