Product image of Kinpeygo (Budesonide) supplied by GNH India

Kinpeygo

Active Ingredient:
Budesonide
Origin:
EU

Kinpeygo (Budesonide)

Budesonide, the active ingredient in Kinpeygo, is a corticosteroid presented as an oral formulation for oral use. It is indicated for the treatment of inflammatory bowel disease, specifically Crohn's disease and ulcerative colitis, helping to reduce intestinal inflammation and maintain remission in adult patients.

GNH India supplies Kinpeygo as a licensed, GDP‑compliant international pharmaceutical supplier, providing the product to hospitals, pharmacies and clinics worldwide under EU quality standards. The company ensures consistent batch release and regulatory compliance for global distribution.

Manufacturer / TM Owner

Stada Arzneimittel Ag

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Indications & Clinical Uses

  • Budesonide is a corticosteroid that reduces gastrointestinal inflammation in inflammatory bowel disease.
  • Crohn's disease: reduces intestinal inflammation and promotes remission.
  • Ulcerative colitis: helps achieve clinical remission and mucosal healing.
  • Inflammatory bowel disease: provides overall disease activity control.

How It Works

  • Budesonide exerts its anti‑inflammatory effect by binding to intracellular glucocorticoid receptors, forming a complex that translocates to the nucleus and modulates gene transcription. This action suppresses the production of pro‑inflammatory cytokines, chemokines and adhesion molecules, while enhancing anti‑inflammatory proteins, leading to decreased leukocyte infiltration and reduced edema in the gastrointestinal mucosa.

Side Effects

Adverse reactions to Kinpeygo may vary in frequency and severity.

Common Side Effects

  • Nausea
  • Headache
  • Abdominal pain
  • Upper respiratory tract infection

Serious or Rare Side Effects

  • Adrenal suppression
  • Severe infections
  • Perforated gastrointestinal ulcer

Precautions & Warnings

  • When using Kinpeygo, consider the following precautions.
  • Assess adrenal function: evaluate baseline cortisol levels before long‑term therapy.
  • Monitor for infections: watch for signs of bacterial, viral or fungal infections during treatment.
  • Evaluate bone health: consider calcium and vitamin D supplementation for patients at risk of osteoporosis.
  • Use with caution in hepatic impairment: dose adjustment may be required in moderate liver disease.
  • Store at ambient temperature: keep in the original container, protect from moisture and light.

Avoid Interactions

Kinpeygo may interact with other medicines; review the following.

Major Interactions (Avoid)

  • Strong CYP3A4 inhibitors (e.g., ketoconazole, itraconazole): may increase systemic exposure.
  • Systemic immunosuppressants (e.g., azathioprine) when combined may heighten infection risk.

Moderate Interactions (Monitor Closely)

  • CYP3A4 inducers (e.g., rifampicin): may reduce budesonide effectiveness.
  • Anticoagulants (e.g., warfarin): may require INR monitoring.
  • NSAIDs: may increase risk of gastrointestinal ulceration.

Frequently Asked Questions

Kinpeygo contains the corticosteroid budesonide and is prescribed for the management of inflammatory bowel disease. It is specifically indicated to treat Crohn's disease and ulcerative colitis by reducing intestinal inflammation and helping patients achieve and maintain remission.

Budesonide binds to intracellular glucocorticoid receptors, forming a complex that moves into the cell nucleus. There it alters gene transcription, suppressing pro‑inflammatory cytokines and chemokines while increasing anti‑inflammatory proteins, which together diminish leukocyte infiltration and edema in the gastrointestinal tract.

The dose of Kinpeygo is individualized. A prescribing physician determines the appropriate amount based on the severity of the disease, patient weight, response to therapy, and other clinical factors. No standard dosage can be provided without a specific medical prescription.

Safety data for budesonide in pregnancy and lactation are limited, and the product is classified as having an unknown pregnancy category. Use during pregnancy or while breastfeeding should only occur if the potential benefit justifies the potential risk, and it must be decided by a qualified healthcare professional.

To order Kinpeygo, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, and will request verification of trade or institutional credentials. The sales team then replies with pricing, availability, shipping details and any necessary import documentation.

Kinpeygo delivers a locally acting corticosteroid with high first‑pass metabolism, offering anti‑inflammatory effects while limiting systemic exposure compared with systemic steroids such as prednisone. It is often used when mesalamine or immunomodulators are insufficient, providing an alternative to biologic agents for patients needing targeted inflammation control.

Kinpeygo should be stored at ambient temperature, preferably below 25 °C. Keep the product in its original packaging, protect it from moisture and direct light, and ensure the container is tightly closed when not in use.

Kinpeygo is taken orally. The tablet or capsule should be swallowed whole with water, and it may be taken with or without food according to the prescribing physician’s instructions.

The most serious risks include adrenal suppression, which can affect the body’s stress response; severe infections due to immunosuppression; and the rare possibility of a perforated gastrointestinal ulcer. Patients should be monitored closely for signs of these conditions.

Kinpeygo should be avoided in individuals with a known hypersensitivity to budesonide or any component of the formulation, in patients with uncontrolled systemic fungal infections, and in those with severe, active infections where immunosuppression could worsen the condition.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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