Product image of Kitonail (Ciclopirox) supplied by GNH India

Kitonail

Active Ingredient:
Ciclopirox
Origin:
EU

Kitonail (Ciclopirox)

Ciclopirox, the active ingredient in Kitonail, is an antifungal presented as a topical formulation for cutaneous use. It treats onychomycosis of the toenails and fingernails in adult patients.
GNH India supplies Kitonail as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Polichem S.A.

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Indications & Clinical Uses

Ciclopirox is an antifungal agent used to treat fungal infections of the nail.

  • Distal subungual onychomycosis: improves nail appearance and clears infection.
  • Proximal subungual onychomycosis: reduces fungal load and promotes healthy nail growth.
  • Total dystrophic onychomycosis: helps restore nail integrity and prevents further fungal spread.

How It Works

  • Ciclopirox inhibits the synthesis of fungal sterols, disrupting the cell membrane structure and function. This interference leads to increased membrane permeability, loss of essential intracellular components, and ultimately fungal cell death, limiting the spread of infection in the nail unit.

Side Effects

Ciclopirox may cause local adverse reactions at the application site.

Common Side Effects

  • Application site irritation: mild redness or discomfort.
  • Itching: transient pruritus at the treated nail.
  • Burning sensation: brief heat feeling after application.
  • Dryness: skin around the nail may become dry.
  • Discoloration: temporary staining of the nail plate.
  • Contact dermatitis: mild allergic skin reaction.

Serious or Rare Side Effects

  • Severe allergic reaction: swelling, hives, or difficulty breathing.
  • Acute urticaria: sudden widespread hives.
  • Stevens‑Johnson syndrome: rare severe skin reaction.
  • Photosensitivity: heightened skin sensitivity to sunlight.
  • Persistent edema: swelling that does not resolve.
  • Systemic toxicity: extremely rare systemic effects.

Precautions & Warnings

Before using Kitonail, consider the following safety measures.

  • Pregnancy: consult a healthcare professional before use.
  • Breastfeeding: discuss potential risks with a physician.
  • Skin integrity: avoid application on broken or inflamed skin.
  • Eyes and mucous membranes: do not apply near eyes or oral cavity.
  • Severe irritation: discontinue use and seek medical advice if intense reactions occur.
  • Store at room temperature: keep in the original container, protect from moisture and light.

Avoid Interactions

Ciclopirox may interact with other substances applied to the nail or skin.

Major Interactions (Avoid)

  • Concurrent use with other topical irritants: may increase local irritation.
  • Combination with photosensitizing agents: heightened risk of photosensitivity.

Moderate Interactions (Monitor Closely)

  • Use with occlusive dressings: may increase drug absorption.
  • Application alongside other nail cosmetics: could reduce efficacy.
  • Co‑administration with systemic antifungals: monitor for additive toxicity.

Frequently Asked Questions

Kitonail contains ciclopirox, an antifungal medication indicated for the treatment of onychomycosis, a fungal infection of the toenails and fingernails. It is applied topically to the affected nail to reduce fungal growth and improve nail appearance.

Ciclopirox works by inhibiting the synthesis of fungal sterols, which are essential components of the cell membrane. This disruption compromises membrane integrity, leading to leakage of cellular contents and ultimately causing fungal cell death.

The dosing regimen for Kitonail is determined by the prescribing healthcare professional based on the severity of the infection and patient-specific factors. Patients should follow the prescriber’s instructions and the product labeling for application frequency and duration.

Safety of ciclopirox in pregnancy or while breastfeeding has not been fully established. Women who are pregnant, planning to become pregnant, or nursing should discuss potential risks and benefits with their healthcare provider before using Kitonail.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, confirming trade or institutional credentials before providing pricing, availability, shipping details, and necessary import documentation.

Kitonail’s active ingredient, ciclopirox, offers a broad spectrum of antifungal activity and is applied topically, avoiding systemic exposure. Compared with oral antifungals, it has a lower risk of systemic side effects but may require longer treatment duration for complete cure.

Kitonail should be stored at room temperature, below 25 °C, in its original packaging. Keep the product away from moisture and direct sunlight, and ensure the container is tightly closed when not in use to maintain product stability.

Kitonail is applied directly to the affected nail and surrounding skin. The prescribed amount is spread evenly over the nail surface, usually once daily, after cleaning and drying the nail. Patients should follow the specific application instructions provided by their healthcare professional.

Serious risks, though rare, include severe allergic reactions such as swelling, hives, or difficulty breathing, as well as rare skin conditions like Stevens‑Johnson syndrome. If any signs of a serious reaction occur, discontinue use immediately and seek medical attention.

Kitonail should not be used by individuals with known hypersensitivity to ciclopirox or any component of the formulation. It is also contraindicated on broken, inflamed, or infected skin, and should be avoided in patients who have experienced severe allergic reactions to similar topical antifungals.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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