Product image of Kitonail (Ciclopirox) supplied by GNH India

Kitonail

Active Ingredient:
Ciclopirox
Origin:
EU

Kitonail (Ciclopirox)

Ciclopirox, the active ingredient in Kitonail, is an antifungal presented as a topical formulation for topical use. It treats fungal infections of the nails and skin in adults and children as prescribed.
GNH India supplies Kitonail as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Polichem S.A.

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Indications & Clinical Uses

  • Ciclopirox is an antifungal that acts on dermatophyte and yeast infections of the skin and nails.
  • Onychomycosis: reduces fungal growth in infected nails, improving nail appearance.
  • Dermatophytosis: clears fungal infection of the skin, relieving redness and scaling.
  • Tinea pedis: eliminates the causative fungus on the feet, reducing itching and maceration.

How It Works

  • Ciclopirox inhibits fungal enzyme systems involved in sterol synthesis and chelates metal ions, disrupting cell membrane function and leading to fungal cell death. By targeting multiple biochemical pathways, it prevents fungal growth and replication on the treated area.

Side Effects

Ciclopirox may cause local skin reactions when applied.

Common Side Effects

  • Burning sensation at the application site.
  • Itching or pruritus.
  • Redness or erythema.
  • Dryness or peeling of the skin.
  • Mild irritation or stinging.
  • Local swelling.

Serious or Rare Side Effects

  • Severe allergic reaction (e.g., angioedema, anaphylaxis).
  • Contact dermatitis with blistering.
  • Extensive skin necrosis.
  • Systemic hypersensitivity reactions.
  • Persistent ulceration at the site.
  • Unexplained fever or malaise.

Precautions & Warnings

Ciclopirox should be used according to medical guidance and with attention to potential risks.

  • Application area: apply only to affected skin or nails as directed.
  • Contraindication: avoid use if known hypersensitivity to ciclopirox or formulation components.
  • Pregnancy: safety not established; consult a healthcare professional before use.
  • Breastfeeding: limited data; discuss risks with a physician.
  • Drug interactions: inform provider of all topical or systemic antifungal agents being used.

Store at below 25°C: keep in the original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Ciclopirox may interact with other agents applied to the skin.

Major Interactions (Avoid)

  • Concurrent use with other topical antifungal medications may increase irritation.
  • Application over damaged skin with systemic antifungal therapy can enhance systemic absorption.

Moderate Interactions (Monitor Closely)

  • Use with topical corticosteroids may mask signs of infection.
  • Co‑administration with systemic antifungals (e.g., itraconazole) may require monitoring for additive effects.
  • Interaction with adhesive dressings may affect drug delivery.
  • Use with other metal‑chelating agents may alter efficacy.

Frequently Asked Questions

Kitonail contains ciclopirox, a topical antifungal indicated for the treatment of onychomycosis (fungal nail infection), dermatophytosis (skin fungal infection), and tinea pedis (athlete's foot). It works by eliminating the causative fungi on the affected area.

Ciclopirox inhibits fungal enzyme systems involved in sterol synthesis and chelates metal ions, disrupting the fungal cell membrane and leading to cell death. This multi‑target action reduces fungal growth on the skin or nails.

The dosage and frequency of Kitonail are determined by the prescribing healthcare professional based on the specific indication, severity of infection, and patient characteristics. Patients should follow the instructions provided by their prescriber.

Safety of ciclopirox in pregnancy and lactation has not been fully established. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss potential risks and benefits with their healthcare provider before using Kitonail.

To request Kitonail, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and import documentation.

Kitonail’s active ingredient, ciclopirox, offers a broad spectrum of activity against dermatophytes and yeasts and works by a distinct mechanism of metal‑ion chelation. Compared with azole or allylamine topical agents, ciclopirox may be effective where resistance to other classes is observed.

Kitonail should be stored at temperatures below 25 °C, in its original packaging, protected from moisture and direct sunlight. Keep the container tightly closed and out of reach of children.

Kitonail is applied topically to the affected skin or nails as directed by a healthcare professional. The area should be clean and dry before application, and the recommended amount should be spread evenly and allowed to dry.

Serious adverse reactions, though rare, include severe allergic responses such as angioedema, anaphylaxis, and extensive contact dermatitis. Patients should seek immediate medical attention if they experience swelling, difficulty breathing, or widespread skin reactions.

Individuals with a known hypersensitivity to ciclopirox or any component of the formulation should avoid using Kitonail. It is also contraindicated on severely damaged skin or mucous membranes without medical supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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