Product image of Kivizidiale (Timolol, Travoprost) supplied by GNH India

Kivizidiale

Active Ingredient:
Timolol, Travoprost
Origin:
EU

Kivizidiale (Timolol, Travoprost)

Timolol, the active ingredient in Kivizidiale, is a beta blocker/prostaglandin analog combination presented as a eye drops for ocular use. It treats primary open-angle glaucoma and ocular hypertension.\n\nGNH India supplies Kivizidiale as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Bausch + Lomb Ireland Limited

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

  • Kivizidiale is indicated for conditions involving elevated intra‑ocular pressure within the glaucoma and ocular hypertension disease family.\n\nPrimary open-angle glaucoma: reduces intra‑ocular pressure to slow optic nerve damage.\nOcular hypertension: lowers intra‑ocular pressure to prevent progression to glaucoma.

How It Works

  • Timolol non‑selectively blocks β‑adrenergic receptors in the ciliary body, decreasing aqueous humor production, while Travoprost, a prostaglandin F2α analog, enhances uveoscleral outflow of aqueous humor. The combined actions result in a net reduction of intra‑ocular pressure.

Side Effects

  • Kivizidiale may cause ocular and systemic adverse reactions.\n\nCommon Side Effects:\n- Eye irritation or burning sensation\n- Transient blurred vision\n- Conjunctival hyperemia\n- Increased eyelash growth\n\nSerious or Rare Side Effects:\n- Severe allergic reaction (e.g., angio‑edema)\n- Bronchospasm or worsening asthma\n- Marked bradycardia or systemic hypotension

Precautions & Warnings

  • Before prescribing Kivizidiale, clinicians should consider several safety aspects.\n\nAssess cardiovascular status: evaluate patients with severe bradycardia or heart block.\nMonitor respiratory conditions: use caution in individuals with asthma or COPD.\nCheck for sulfonamide allergy: avoid if known hypersensitivity exists.\nAvoid use in patients with narrow-angle glaucoma.\nPregnancy and lactation: safety not established; use only if benefit outweighs risk.\nStore at room temperature: keep in original container, protect from light and moisture.

Avoid Interactions

  • Kivizidiale can interact with other medicines, requiring attention to potential additive effects.\n\nMajor Interactions (Avoid):\n- Non‑selective beta‑blockers (e.g., propranolol): risk of additive bradycardia or hypotension.\n- Other intra‑ocular pressure‑lowering agents (e.g., apraclonidine): may cause excessive ocular hypotension.\n- Sympathomimetic eye drops (e.g., epinephrine): may diminish timolol efficacy.\n\nModerate Interactions (Monitor Closely):\n- Systemic carbonic anhydrase inhibitors: possible additive IOP reduction.\n- Anticholinergic eye drops: may affect ocular surface tolerance.\n- MAO inhibitors: monitor for systemic cardiovascular effects.

Frequently Asked Questions

Kivizidiale is a prescription eye‑drop formulation that combines timolol and travoprost to lower intra‑ocular pressure. It is used primarily in the management of primary open‑angle glaucoma and ocular hypertension, helping to prevent optic nerve damage and preserve visual function.

Timolol reduces the production of aqueous humor by blocking β‑adrenergic receptors in the eye, while travoprost, a prostaglandin F2α analogue, increases uveoscleral outflow of aqueous humor. The dual mechanism results in a net decrease in intra‑ocular pressure.

The specific dosing regimen for Kivizidiale is determined by the prescribing clinician. Typically, one drop is instilled in the affected eye(s) once daily, but the exact dose and frequency should follow the healthcare professional’s instructions.

Safety data for Kivizidiale during pregnancy and lactation are limited. It should only be used when the potential benefit justifies any possible risk to the fetus or infant, and the decision must be made by a qualified healthcare provider.

To order Kivizidiale, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Kivizidiale combines a beta‑blocker and a prostaglandin analogue in a single formulation, offering the IOP‑lowering benefits of both classes. Compared with monotherapy agents, the combination can achieve greater pressure reduction, potentially simplifying treatment regimens for patients who need dual‑mechanism therapy.

Kivizidiale eye drops should be stored at room temperature, away from direct sunlight and moisture. Keep the bottle tightly closed in its original packaging until use, and discard any solution that appears discolored or contaminated.

Kivizidiale is administered topically to the eye. The usual method is to instill one drop into the prescribed eye(s) using the provided dropper, taking care not to touch the tip of the bottle to the ocular surface or any other object.

Serious adverse events associated with Kivizidiale include severe allergic reactions such as angio‑edema, bronchospasm or worsening asthma, marked bradycardia, systemic hypotension, and rare ocular changes like iris pigmentation or periorbital fat atrophy. Patients should seek immediate medical attention if these occur.

Kivizidiale should be avoided in individuals with known hypersensitivity to timolol, travoprost or any excipients, patients with severe asthma or chronic obstructive pulmonary disease, those with sinus bradycardia or heart block, and persons with narrow‑angle glaucoma.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.