Klacid (Clarithromycin)

Clarithromycin inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit. This blocks the translocation step of peptide chain elongation, producing a bacteriostatic effect that limits bacterial growth and assists the immune system in clearing the infection.

The dosage of Klacid is determined by the prescribing clinician based on the specific infection, patient weight, renal and hepatic function, and local treatment guidelines. Patients should follow the prescriber’s instructions and not adjust the dose on their own.

Clarithromycin is classified as pregnancy category B, indicating that animal studies have not shown risk but there are limited human data. It may be used during pregnancy or lactation only when the potential benefit justifies any possible risk to the fetus or infant.

To order Klacid, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Klacid (clarithromycin) and azithromycin are both macrolide antibiotics, but clarithromycin generally has a broader spectrum against certain Gram‑positive organisms and a higher potential for drug‑drug interactions via CYP3A4. Azithromycin often requires fewer doses and may have a lower risk of QT prolongation, while clarithromycin may be preferred for specific resistant strains.

Klacid tablets should be stored at ambient temperature below 25 °C, in the original container, protected from moisture and light. Keep the product out of reach of children and avoid exposure to excessive heat or humidity.

Klacid is taken orally, usually with a full glass of water. It may be taken with or without food, but taking it with food can reduce gastrointestinal upset. Patients should swallow the tablet whole and not crush or chew it unless directed by a healthcare professional.

Serious risks include severe allergic reactions such as rash, itching, swelling, or anaphylaxis; liver injury presenting as jaundice or elevated liver enzymes; and cardiac arrhythmias, particularly QT‑interval prolongation that can lead to torsades de pointes. Any of these symptoms require immediate medical attention.

Klacid should be avoided in patients with a known hypersensitivity to clarithromycin, other macrolides, or any component of the formulation. It is also contraindicated in individuals with a history of significant QT prolongation or ventricular arrhythmias, and in those taking drugs that strongly interact via CYP3A4 without appropriate monitoring.