Klacid Rm (Clarithromycin)

Clarithromycin binds to the 50S ribosomal subunit of susceptible bacteria, inhibiting the translocation step of protein synthesis. This blocks the formation of new proteins, resulting in a bacteriostatic effect that limits bacterial growth and allows the immune system to clear the infection.

The specific dose of Klacid Rm is determined by the prescribing clinician based on the infection type, severity, patient age, weight, renal and hepatic function, and local guidelines. Patients should follow the prescriber’s instructions and the product label.

Clarithromycin is classified as Pregnancy Category B, indicating no evidence of risk in animal studies but limited human data. It may be used during pregnancy only if clearly needed. Clarithromycin passes into breast milk; breastfeeding mothers should discuss potential risks with their healthcare provider.

To order Klacid Rm, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Klacid Rm (clarithromycin) offers a broader spectrum against atypical pathogens compared with erythromycin and has improved acid stability, allowing once‑ or twice‑daily dosing. Its drug‑interaction profile is similar to other macrolides, but it may have a higher potential for CYP3A4‑mediated interactions than azithromycin.

Klacid Rm should be stored at ambient temperature, below 25 °C, in its original packaging. Protect the product from moisture, direct sunlight and excessive heat to maintain its stability and potency throughout its shelf life.

Klacid Rm is taken orally, usually with a full glass of water. It may be taken with or without food, but consistent administration with respect to meals can help reduce gastrointestinal upset. Patients should swallow tablets whole and not crush or chew them unless instructed otherwise.

Serious risks include hepatotoxicity, QT‑interval prolongation leading to cardiac arrhythmias, severe allergic reactions such as anaphylaxis, Clostridioides difficile‑associated colitis, and rare dermatologic emergencies like Stevens‑Johnson syndrome. Patients should seek immediate medical attention if they experience symptoms such as jaundice, palpitations, severe diarrhea, or skin blistering.

Klacid Rm should be avoided in patients with known hypersensitivity to clarithromycin or other macrolides, those with a history of prolonged QT interval or significant electrolyte disturbances, and individuals taking medications that have contraindicated interactions, such as certain statins or antiarrhythmics, unless closely monitored.