Klacid Uno (Clarithromycin)

Clarithromycin binds to the 50S ribosomal subunit of bacteria, blocking the translocation step of protein synthesis. This inhibition halts bacterial growth, producing a bacteriostatic effect that allows the immune system to clear the infection.

The prescribed dose of Klacid Uno is determined by the treating clinician based on the infection type, severity, patient age, renal and hepatic function, and local guidelines. Patients should follow the prescriber’s instructions and not adjust the dose on their own.

Clarithromycin is classified as pregnancy category B, indicating no evidence of risk in animal studies but insufficient human data. It may be used during pregnancy only if the potential benefit justifies the risk. Breastfeeding mothers should consult a healthcare professional, as clarithromycin is excreted in milk.

To request Klacid Uno, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Clarithromycin offers a broader spectrum against certain Gram‑negative organisms and better tissue penetration compared with older macrolides like erythromycin. It also has a more convenient dosing schedule. However, drug‑interaction potential and QT‑prolongation risk may be higher than some alternatives, requiring careful patient selection.

Klacid Uno tablets should be stored at temperatures below 25 °C, in the original packaging, and protected from moisture and direct sunlight. Keeping the product in a dry, cool environment maintains its stability and potency throughout its shelf life.

Klacid Uno is taken orally, usually with or without food as directed by the prescriber. The tablets should be swallowed whole with a full glass of water. Patients should not crush or chew the tablets unless specifically instructed.

Serious risks include severe allergic reactions such as anaphylaxis, Clostridioides difficile‑associated colitis, and cardiac events like QT interval prolongation that can lead to arrhythmias. Patients should seek immediate medical attention if they experience symptoms such as rash, persistent diarrhea, or palpitations.

Klacid Uno should be avoided in individuals with a known hypersensitivity to clarithromycin, other macrolides, or any component of the formulation. It is also contraindicated in patients taking medications that strongly prolong the QT interval, such as cisapride or pimozide, unless the benefits outweigh the risks.